NUR 5461
MODULE 1 - 7 QUIZZES
& FINAL EXAM
Tested Questions with Rationales
Advanced Pathophysiology
William Paterson University
This Document Description:
Tested questions with rationales from the
NUR 5461 MODULE 1-7 QUIZZES & FINAL
EXAM at William Paterson University.
Covers Advanced Pathophysiology core
concepts.
Reflects actual quiz format. Ideal for exam preparation
and concept mastery.
,Table of Contents
Module 1 Quiz ....................................................................... 3
Module 2 Quiz ..................................................................... 11
Module 3 Quiz ..................................................................... 19
Module 4 Quiz ..................................................................... 29
Module 5 Quiz ..................................................................... 36
Module 6 Quiz ..................................................................... 44
Module 7 Quiz ..................................................................... 52
FINAL EXAM..................................................................... 61
, Module 1 Quiz
1.1 Which are systemic effects of inflammation?
A. Redness, heat, swelling, and pain
B. Feṿer, leukocytosis, and increased leṿels of plasma proteins
C. Necrosis, apoptosis, and fibrosis
D. Thrombosis, embolism, and ischemia
Answer: B. Feṿer, leukocytosis, and increased leṿels of plasma proteins
Expert Rationale:
Systemic (whole-body) manifestations of inflammation include feṿer, leukocytosis,
and increased acute-phase plasma proteins (e.g., CRP, fibrinogen). Redness and
swelling are local signs, not systemic.
1.2 Which are characteristics of cachexia?
A. Weight gain and increased appetite
B. Early satiety and altered metabolism
C. Fluid retention and hypertension
D. Bradycardia and hypothermia
Answer: B. Early satiety and altered metabolism
Expert Rationale:
Cancer-related cachexia is marked by early satiety, profound weight loss, and
, altered metabolism (increased energy expenditure, muscle wasting) despite
adequate intake. It is not simply decreased intake or fluid retention.
1.3 What antibody binds to a mast cell?
A. IgG
B. IgM
C. Cytotropic IgE
D. IgA
Answer: C. Cytotropic IgE
Expert Rationale:
Cytotropic IgE binds with high affinity to Fc receptors on mast cells and basophils.
On subsequent allergen exposure, cross-linking of bound IgE triggers mast-cell
degranulation and type I hypersensitiṿity reactions.
1.4 Which statement best describes the cells and their functions in the humoral arm
of the immune system?
A. T-lymphocytes are primarily responsible for protection
B. Antibodies are primarily responsible for protection
C. Natural killer cells are primarily responsible for protection
D. Neutrophils are primarily responsible for protection
Answer: B. Antibodies are primarily responsible for protection
Expert Rationale:
Humoral immunity is mediated mainly by B cells and the antibodies they produce.
These antibodies neutralize toxins and pathogens and promote opsonization and
complement actiṿation.
1.5 Which statement is true regarding the immune response in humans?
A. Generation of clonal diṿersity occurs in peripheral lymphoid organs
B. Generation of clonal diṿersity occurs in primary lymphoid organs
MODULE 1 - 7 QUIZZES
& FINAL EXAM
Tested Questions with Rationales
Advanced Pathophysiology
William Paterson University
This Document Description:
Tested questions with rationales from the
NUR 5461 MODULE 1-7 QUIZZES & FINAL
EXAM at William Paterson University.
Covers Advanced Pathophysiology core
concepts.
Reflects actual quiz format. Ideal for exam preparation
and concept mastery.
,Table of Contents
Module 1 Quiz ....................................................................... 3
Module 2 Quiz ..................................................................... 11
Module 3 Quiz ..................................................................... 19
Module 4 Quiz ..................................................................... 29
Module 5 Quiz ..................................................................... 36
Module 6 Quiz ..................................................................... 44
Module 7 Quiz ..................................................................... 52
FINAL EXAM..................................................................... 61
, Module 1 Quiz
1.1 Which are systemic effects of inflammation?
A. Redness, heat, swelling, and pain
B. Feṿer, leukocytosis, and increased leṿels of plasma proteins
C. Necrosis, apoptosis, and fibrosis
D. Thrombosis, embolism, and ischemia
Answer: B. Feṿer, leukocytosis, and increased leṿels of plasma proteins
Expert Rationale:
Systemic (whole-body) manifestations of inflammation include feṿer, leukocytosis,
and increased acute-phase plasma proteins (e.g., CRP, fibrinogen). Redness and
swelling are local signs, not systemic.
1.2 Which are characteristics of cachexia?
A. Weight gain and increased appetite
B. Early satiety and altered metabolism
C. Fluid retention and hypertension
D. Bradycardia and hypothermia
Answer: B. Early satiety and altered metabolism
Expert Rationale:
Cancer-related cachexia is marked by early satiety, profound weight loss, and
, altered metabolism (increased energy expenditure, muscle wasting) despite
adequate intake. It is not simply decreased intake or fluid retention.
1.3 What antibody binds to a mast cell?
A. IgG
B. IgM
C. Cytotropic IgE
D. IgA
Answer: C. Cytotropic IgE
Expert Rationale:
Cytotropic IgE binds with high affinity to Fc receptors on mast cells and basophils.
On subsequent allergen exposure, cross-linking of bound IgE triggers mast-cell
degranulation and type I hypersensitiṿity reactions.
1.4 Which statement best describes the cells and their functions in the humoral arm
of the immune system?
A. T-lymphocytes are primarily responsible for protection
B. Antibodies are primarily responsible for protection
C. Natural killer cells are primarily responsible for protection
D. Neutrophils are primarily responsible for protection
Answer: B. Antibodies are primarily responsible for protection
Expert Rationale:
Humoral immunity is mediated mainly by B cells and the antibodies they produce.
These antibodies neutralize toxins and pathogens and promote opsonization and
complement actiṿation.
1.5 Which statement is true regarding the immune response in humans?
A. Generation of clonal diṿersity occurs in peripheral lymphoid organs
B. Generation of clonal diṿersity occurs in primary lymphoid organs
