AAVSB PAVE QSE COMPREHENSIVE
STUDY GUIDE QUESTIONS AND
DETAILED SOLUTIONS LATEST
UPDATE
1. Which of the following is the primary mechanism of action for aminoglycoside antibiotics?
A. Inhibition of cell wall synthesis
B. Inhibition of DNA gyrase
C. Binding to the 30S ribosomal subunit to inhibit protein synthesis
D. Disruption of the fungal cell membrane
Answer: C
Conceptual Explanation: Aminoglycosides bind irreversibly to the 30S ribosomal subunit,
causing mRNA misreading and inhibition of protein synthesis.
2. In the mammalian kidney, where is the majority of glucose reabsorbed?
A. Distal convoluted tubule
B. Loop of Henle
C. Collecting duct
D. Proximal convoluted tubule
,Answer: D
Conceptual Explanation: The proximal convoluted tubule is responsible for reabsorbing
nearly 100% of filtered glucose via sodium-glucose cotransporters.
3. Which nerve provides motor innervation to the muscles that extend the carpus and digits
in the dog?
A. Median nerve
B. Ulnar nerve
C. Radial nerve
D. Musculocutaneous nerve
Answer: C
Conceptual Explanation: The radial nerve innervates the extensors of the elbow, carpus,
and digits.
4. What type of necrosis is most characteristic of hypoxic injury in the central nervous
system?
A. Coagulative necrosis
B. Liquefactive necrosis
C. Caseous necrosis
D. Fat necrosis
Answer: B
, Conceptual Explanation: Liquefactive necrosis occurs in the CNS because of the high lipid
content and lack of a strong connective tissue framework.
5. Which enzyme is considered the rate-limiting step of glycolysis?
A. Phosphofructokinase-1
B. Pyruvate kinase
C. Hexokinase
D. Aldolase
Answer: A
Conceptual Explanation: Phosphofructokinase-1 (PFK-1) is the primary regulatory and
rate-limiting enzyme of the glycolytic pathway.
6. Which of the following describes a Type I hypersensitivity reaction?
A. IgG-mediated cytotoxic reaction
B. Immune complex-mediated reaction
C. T-cell mediated delayed reaction
D. IgE-mediated mast cell degranulation
Answer: D
Conceptual Explanation: Type I hypersensitivity involves IgE antibodies binding to mast
cells, leading to degranulation upon allergen exposure.
STUDY GUIDE QUESTIONS AND
DETAILED SOLUTIONS LATEST
UPDATE
1. Which of the following is the primary mechanism of action for aminoglycoside antibiotics?
A. Inhibition of cell wall synthesis
B. Inhibition of DNA gyrase
C. Binding to the 30S ribosomal subunit to inhibit protein synthesis
D. Disruption of the fungal cell membrane
Answer: C
Conceptual Explanation: Aminoglycosides bind irreversibly to the 30S ribosomal subunit,
causing mRNA misreading and inhibition of protein synthesis.
2. In the mammalian kidney, where is the majority of glucose reabsorbed?
A. Distal convoluted tubule
B. Loop of Henle
C. Collecting duct
D. Proximal convoluted tubule
,Answer: D
Conceptual Explanation: The proximal convoluted tubule is responsible for reabsorbing
nearly 100% of filtered glucose via sodium-glucose cotransporters.
3. Which nerve provides motor innervation to the muscles that extend the carpus and digits
in the dog?
A. Median nerve
B. Ulnar nerve
C. Radial nerve
D. Musculocutaneous nerve
Answer: C
Conceptual Explanation: The radial nerve innervates the extensors of the elbow, carpus,
and digits.
4. What type of necrosis is most characteristic of hypoxic injury in the central nervous
system?
A. Coagulative necrosis
B. Liquefactive necrosis
C. Caseous necrosis
D. Fat necrosis
Answer: B
, Conceptual Explanation: Liquefactive necrosis occurs in the CNS because of the high lipid
content and lack of a strong connective tissue framework.
5. Which enzyme is considered the rate-limiting step of glycolysis?
A. Phosphofructokinase-1
B. Pyruvate kinase
C. Hexokinase
D. Aldolase
Answer: A
Conceptual Explanation: Phosphofructokinase-1 (PFK-1) is the primary regulatory and
rate-limiting enzyme of the glycolytic pathway.
6. Which of the following describes a Type I hypersensitivity reaction?
A. IgG-mediated cytotoxic reaction
B. Immune complex-mediated reaction
C. T-cell mediated delayed reaction
D. IgE-mediated mast cell degranulation
Answer: D
Conceptual Explanation: Type I hypersensitivity involves IgE antibodies binding to mast
cells, leading to degranulation upon allergen exposure.
