AAVSB PAVE QUALIFYING SCIENCE
EXAM (QSE) COMPREHENSIVE
PRACTICE QUESTIONS AND DETAILED
SOLUTIONS LATEST UPDATE
1. Which of the following cell types in the stomach is responsible for the secretion of
hydrochloric acid (HCl) and intrinsic factor?
A. Chief cells
B. Mucous neck cells
C. G cells
D. Parietal cells
Answer: D
Conceptual Explanation: Parietal cells (oxyntic cells) secrete HCl and intrinsic factor.
Chief cells secrete pepsinogen, G cells secrete gastrin, and mucous neck cells secrete mucus.
2. In the canine, which cranial nerve is responsible for the motor innervation of the muscles
of mastication?
A. CN V (Trigeminal) - Mandibular branch
B. CN IX (Glossopharyngeal)
C. CN VII (Facial)
,D. CN XII (Hypoglossal)
Answer: A
Conceptual Explanation: The mandibular branch of the Trigeminal nerve (CN V) provides
motor innervation to the muscles of mastication (masseter, temporal, pterygoids, and
rostral digastricus).
3. What is the primary mechanism of action of Fluoroquinolone antibiotics like Enrofloxacin?
A. Inhibition of 30S ribosomal subunits
B. Disruption of the bacterial cell wall synthesis
C. Binding to 50S ribosomal subunits
D. Inhibition of DNA gyrase (Topoisomerase II)
Answer: D
Conceptual Explanation: Fluoroquinolones inhibit DNA gyrase and Topoisomerase IV,
preventing bacterial DNA supercoiling and synthesis.
4. Which of the following is a hallmark of Type II Hypersensitivity reactions?
A. IgE-mediated mast cell degranulation
B. T-cell mediated delayed response
C. Immune complex deposition in blood vessels
D. Cytotoxic antibodies (IgG or IgM) targeting cell surface antigens
, Answer: D
Conceptual Explanation: Type II hypersensitivity involves antibody-mediated destruction
of cells (e.g., IMHA). Type I is IgE-mediated, Type III is immune complex, and Type IV is cell-
mediated.
5. Which clotting factor is unique to the Extrinsic Pathway of the coagulation cascade?
A. Factor XII
B. Factor IX
C. Factor X
D. Factor VII
Answer: D
Conceptual Explanation: Factor VII is the primary factor of the extrinsic pathway,
activated by Tissue Factor. Factors XII and IX are intrinsic; Factor X is the start of the
common pathway.
6. A deficiency in which of the following vitamins is most commonly associated with
‘Stargazing’ (polioencephalomalacia) in ruminants secondary to high sulfur intake?
A. Vitamin A
B. Vitamin B12 (Cobalamin)
C. Vitamin B1 (Thiamine)
D. Vitamin E
EXAM (QSE) COMPREHENSIVE
PRACTICE QUESTIONS AND DETAILED
SOLUTIONS LATEST UPDATE
1. Which of the following cell types in the stomach is responsible for the secretion of
hydrochloric acid (HCl) and intrinsic factor?
A. Chief cells
B. Mucous neck cells
C. G cells
D. Parietal cells
Answer: D
Conceptual Explanation: Parietal cells (oxyntic cells) secrete HCl and intrinsic factor.
Chief cells secrete pepsinogen, G cells secrete gastrin, and mucous neck cells secrete mucus.
2. In the canine, which cranial nerve is responsible for the motor innervation of the muscles
of mastication?
A. CN V (Trigeminal) - Mandibular branch
B. CN IX (Glossopharyngeal)
C. CN VII (Facial)
,D. CN XII (Hypoglossal)
Answer: A
Conceptual Explanation: The mandibular branch of the Trigeminal nerve (CN V) provides
motor innervation to the muscles of mastication (masseter, temporal, pterygoids, and
rostral digastricus).
3. What is the primary mechanism of action of Fluoroquinolone antibiotics like Enrofloxacin?
A. Inhibition of 30S ribosomal subunits
B. Disruption of the bacterial cell wall synthesis
C. Binding to 50S ribosomal subunits
D. Inhibition of DNA gyrase (Topoisomerase II)
Answer: D
Conceptual Explanation: Fluoroquinolones inhibit DNA gyrase and Topoisomerase IV,
preventing bacterial DNA supercoiling and synthesis.
4. Which of the following is a hallmark of Type II Hypersensitivity reactions?
A. IgE-mediated mast cell degranulation
B. T-cell mediated delayed response
C. Immune complex deposition in blood vessels
D. Cytotoxic antibodies (IgG or IgM) targeting cell surface antigens
, Answer: D
Conceptual Explanation: Type II hypersensitivity involves antibody-mediated destruction
of cells (e.g., IMHA). Type I is IgE-mediated, Type III is immune complex, and Type IV is cell-
mediated.
5. Which clotting factor is unique to the Extrinsic Pathway of the coagulation cascade?
A. Factor XII
B. Factor IX
C. Factor X
D. Factor VII
Answer: D
Conceptual Explanation: Factor VII is the primary factor of the extrinsic pathway,
activated by Tissue Factor. Factors XII and IX are intrinsic; Factor X is the start of the
common pathway.
6. A deficiency in which of the following vitamins is most commonly associated with
‘Stargazing’ (polioencephalomalacia) in ruminants secondary to high sulfur intake?
A. Vitamin A
B. Vitamin B12 (Cobalamin)
C. Vitamin B1 (Thiamine)
D. Vitamin E
