Dosage Forms Exam 1 – Practice Forms 1 & 2 |
Pharmacy Dosage Form Questions & 100% Verified
Answers | Complete Exam Review | 2026–2027
,1. The Biopharmaceutics Classification System (BCS) A. High solubility, High permeability.
places a given active pharmaceutical ingredient in one of
four categories depending on its solubility and permeability
as they pertain to oral dosing. A class I drug is classified as
one possessing:
A. High solubility, High permeability.
B. High solubility, Low permeability.
C. Low solubility, High permeability.
D. High equivalence, Low sedimentation.
2. Which polymer is described as a hydrophilic, semi- D. HPMC
synthetic cellulose derivative used in hydrophilic extended-
release matrices, film coating, and viscosity enhancement?
A. PLGA
B. Chitosan
C. Ethylcellulose
D. HPMC
3. Why is simply maximizing viscosity usually not the D. Excessive viscosity can improve stability but make pouring, withdrawal, transfer,
correct formulation goal? tube flow, or spreading difficult
A. Higher viscosity always makes products chemically
unstable
B. Viscosity has no effect on product use
C. Lower viscosity always provides the most stable product
D. Excessive viscosity can improve stability but make
pouring, withdrawal, transfer, tube flow, or spreading
difficult
4. A formulation becomes increasingly resistant to pumping C. Dilatant shear-thickening
as the rate of movement increases. Which behavior is
most consistent with this finding?
A. Constant Newtonian viscosity
B. Shear-thinning
C. Dilatant shear-thickening
D. Thixotropic recovery at rest
5. Which of the following routes of administration avoids D. Parenteral medications given through infusion.
the First Pass Effect?
A. Oral preparation to deliver drugs in the upper part of the
stomach.
B. Oral preparations to deliver drugs in the small intestine.
C. Oral preparations to deliver drugs in the large intestine.
D. Parenteral medications given through infusion.
6. Which flow behavior is expected for a Newtonian D. Viscosity remains essentially constant
material as shear rate changes?
A. Apparent viscosity always decreases with time
B. A yield stress must be exceeded before any flow
C. Viscosity increases as shear rate increases
D. Viscosity remains essentially constant
7. Which two properties define the Biopharmaceutics B. Aqueous solubility and intestinal permeability
Classification System?
A. Clearance and volume of distribution
B. Aqueous solubility and intestinal permeability
C. Protein binding and half-life
D. Potency and therapeutic index
, 8. Which of the following statements best describes the A. An exemption granted by the FDA from conducting human bioequivalence
rationale for a Biowaiver? studies when the active pharmaceutical ingredient(s) meet certain solubility and
permeability criteria in vitro and when the dissolution profile of the dose form meets
A. An exemption granted by the FDA from conducting the requirements for an "immediate" (IR) release form.
human bioequivalence studies when the active
pharmaceutical ingredient(s) meet certain solubility and
permeability criteria in vitro and when the dissolution
profile of the dose form meets the requirements for an
"immediate" (IR) release form.
B. An exemption granted by the FDA from conducting
human bioavailability studies when the active
pharmaceutical ingredient(s) meet certain solubility and
permeability criteria in vivo and when the dissolution profile
of the dose form meets the requirements for Controlled
Release (CR) form.
C. An exemption granted by the FDA from conducting
human bioequivalence studies when the inactive
ingredient(s) meet certain only permeability criteria in vitro
and when the dissolution profile of the dose form meets
the requirements for a "sustained" (SR) rel
9. Which of the following statements is NOT correct A. Only new chemical entities are considered new drugs by the FDA.
regarding the FDA consideration or definition of a New
Drug?
A. Only new chemical entities are considered new drugs
by the FDA.
B. A change in the dosage schedule or regimen of the drug
already approved constitutes newness under the law for a
New Drug.
C. A proposed new route of administration is considered a
New Drug by the FDA.
D. A new combination of two or more old drugs are
considered New Drugs by the FDA.
10. All else being comparable, how does increasing A. It generally increases the separation rate
particle or droplet size affect physical separation in a
dispersed system?
A. It generally increases the separation rate
B. It always eliminates separation
C. It decreases the separation rate
D. It converts the system to Newtonian flow
11. A laboratory reports that an aqueous preparation B. Osmolarity
contains 305 mOsm/L of dissolved particles. Which
property has been reported?
A. Tonicity
B. Osmolarity
C. Buffer capacity
D. Vapor pressure
12. A parenteral solution is markedly hypotonic to red B. Hemolysis
blood cells. Which adverse cellular effect is most directly
expected?
A. Crenation
B. Hemolysis
C. Sublimation
D. Ion pairing
13. Which statement about plasticizers is correct? D. A plasticizer is a small molecule that can make a polymer film more flexible and
less brittle
A. A plasticizer is the polymer that forms the entire matrix
structure
B. A plasticizer is always used to make a coating more
hydrophobic
C. A plasticizer is synonymous with a rate-controlling
membrane
D. A plasticizer is a small molecule that can make a
polymer film more flexible and less brittle
Pharmacy Dosage Form Questions & 100% Verified
Answers | Complete Exam Review | 2026–2027
,1. The Biopharmaceutics Classification System (BCS) A. High solubility, High permeability.
places a given active pharmaceutical ingredient in one of
four categories depending on its solubility and permeability
as they pertain to oral dosing. A class I drug is classified as
one possessing:
A. High solubility, High permeability.
B. High solubility, Low permeability.
C. Low solubility, High permeability.
D. High equivalence, Low sedimentation.
2. Which polymer is described as a hydrophilic, semi- D. HPMC
synthetic cellulose derivative used in hydrophilic extended-
release matrices, film coating, and viscosity enhancement?
A. PLGA
B. Chitosan
C. Ethylcellulose
D. HPMC
3. Why is simply maximizing viscosity usually not the D. Excessive viscosity can improve stability but make pouring, withdrawal, transfer,
correct formulation goal? tube flow, or spreading difficult
A. Higher viscosity always makes products chemically
unstable
B. Viscosity has no effect on product use
C. Lower viscosity always provides the most stable product
D. Excessive viscosity can improve stability but make
pouring, withdrawal, transfer, tube flow, or spreading
difficult
4. A formulation becomes increasingly resistant to pumping C. Dilatant shear-thickening
as the rate of movement increases. Which behavior is
most consistent with this finding?
A. Constant Newtonian viscosity
B. Shear-thinning
C. Dilatant shear-thickening
D. Thixotropic recovery at rest
5. Which of the following routes of administration avoids D. Parenteral medications given through infusion.
the First Pass Effect?
A. Oral preparation to deliver drugs in the upper part of the
stomach.
B. Oral preparations to deliver drugs in the small intestine.
C. Oral preparations to deliver drugs in the large intestine.
D. Parenteral medications given through infusion.
6. Which flow behavior is expected for a Newtonian D. Viscosity remains essentially constant
material as shear rate changes?
A. Apparent viscosity always decreases with time
B. A yield stress must be exceeded before any flow
C. Viscosity increases as shear rate increases
D. Viscosity remains essentially constant
7. Which two properties define the Biopharmaceutics B. Aqueous solubility and intestinal permeability
Classification System?
A. Clearance and volume of distribution
B. Aqueous solubility and intestinal permeability
C. Protein binding and half-life
D. Potency and therapeutic index
, 8. Which of the following statements best describes the A. An exemption granted by the FDA from conducting human bioequivalence
rationale for a Biowaiver? studies when the active pharmaceutical ingredient(s) meet certain solubility and
permeability criteria in vitro and when the dissolution profile of the dose form meets
A. An exemption granted by the FDA from conducting the requirements for an "immediate" (IR) release form.
human bioequivalence studies when the active
pharmaceutical ingredient(s) meet certain solubility and
permeability criteria in vitro and when the dissolution
profile of the dose form meets the requirements for an
"immediate" (IR) release form.
B. An exemption granted by the FDA from conducting
human bioavailability studies when the active
pharmaceutical ingredient(s) meet certain solubility and
permeability criteria in vivo and when the dissolution profile
of the dose form meets the requirements for Controlled
Release (CR) form.
C. An exemption granted by the FDA from conducting
human bioequivalence studies when the inactive
ingredient(s) meet certain only permeability criteria in vitro
and when the dissolution profile of the dose form meets
the requirements for a "sustained" (SR) rel
9. Which of the following statements is NOT correct A. Only new chemical entities are considered new drugs by the FDA.
regarding the FDA consideration or definition of a New
Drug?
A. Only new chemical entities are considered new drugs
by the FDA.
B. A change in the dosage schedule or regimen of the drug
already approved constitutes newness under the law for a
New Drug.
C. A proposed new route of administration is considered a
New Drug by the FDA.
D. A new combination of two or more old drugs are
considered New Drugs by the FDA.
10. All else being comparable, how does increasing A. It generally increases the separation rate
particle or droplet size affect physical separation in a
dispersed system?
A. It generally increases the separation rate
B. It always eliminates separation
C. It decreases the separation rate
D. It converts the system to Newtonian flow
11. A laboratory reports that an aqueous preparation B. Osmolarity
contains 305 mOsm/L of dissolved particles. Which
property has been reported?
A. Tonicity
B. Osmolarity
C. Buffer capacity
D. Vapor pressure
12. A parenteral solution is markedly hypotonic to red B. Hemolysis
blood cells. Which adverse cellular effect is most directly
expected?
A. Crenation
B. Hemolysis
C. Sublimation
D. Ion pairing
13. Which statement about plasticizers is correct? D. A plasticizer is a small molecule that can make a polymer film more flexible and
less brittle
A. A plasticizer is the polymer that forms the entire matrix
structure
B. A plasticizer is always used to make a coating more
hydrophobic
C. A plasticizer is synonymous with a rate-controlling
membrane
D. A plasticizer is a small molecule that can make a
polymer film more flexible and less brittle
