What inheritance pattern shows vertical transmission in pedigrees?
Autosomal dominant Autosomal dominant disorders appear in every
generation.
What type of mutation causes Fragile X syndrome?
, CGG trinucleotide repeat expansion Repeating CGG segments leads to gene
silencing in Fragile X.
What type of disorders are hemophilia and Duchenne muscular dystrophy?
X-linked recessive Males are affected, mothers are carriers, no male-to-male
transmission.
What are behavioral features of Fragile X?
Autism-like behaviors, hyperactivity, social anxiety Fragile X commonly
overlaps with autism spectrum symptoms.
What does autosomal dominant mean?
One abnormal allele is enough for disease expression Autosomal dominant
traits show if one gene is mutated.
, Which step of protein synthesis occurs at the ribosome and uses tRNA to build a
protein?
Translation Translation occurs at ribosomes; tRNA delivers amino acids to
match mRNA codons, building a protein.
What codon starts translation?
Give this one a try later!
AUG (start codon) AUG codes for methionine, the universal start signal.
What are physical features of Fragile X?
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Long face, large ears, large testes Classic "X-tra large" features include facial
shape, ears, and macroorchidism.
A woman is a carrier for hemophilia A. What percent chance do her sons have of being
affected?
Give this one a try later!
Autosomal dominant Autosomal dominant disorders appear in every
generation.
What type of mutation causes Fragile X syndrome?
, CGG trinucleotide repeat expansion Repeating CGG segments leads to gene
silencing in Fragile X.
What type of disorders are hemophilia and Duchenne muscular dystrophy?
X-linked recessive Males are affected, mothers are carriers, no male-to-male
transmission.
What are behavioral features of Fragile X?
Autism-like behaviors, hyperactivity, social anxiety Fragile X commonly
overlaps with autism spectrum symptoms.
What does autosomal dominant mean?
One abnormal allele is enough for disease expression Autosomal dominant
traits show if one gene is mutated.
, Which step of protein synthesis occurs at the ribosome and uses tRNA to build a
protein?
Translation Translation occurs at ribosomes; tRNA delivers amino acids to
match mRNA codons, building a protein.
What codon starts translation?
Give this one a try later!
AUG (start codon) AUG codes for methionine, the universal start signal.
What are physical features of Fragile X?
Give this one a try later!
Long face, large ears, large testes Classic "X-tra large" features include facial
shape, ears, and macroorchidism.
A woman is a carrier for hemophilia A. What percent chance do her sons have of being
affected?
Give this one a try later!
