ATI Pharmacology Proctored Exam – Most Tested
Questions & 100% Verified Answers with Rationales |
Comprehensive Pharmacology Exam Review |
2026–2027
,A provider prescribes phenobarbital for a client who has a A. One
seizure disorder. The medication has a long half-life of 4
days. How many times per day should the nurse expect to (Medications with long half-lives remain at their therapeutic levels between doses
administer this medication? for long periods of time. The nurse should expect to administer this medication once
a day.)
A. One
B. Two
C. Three
D. Four
A staff educator is reviewing medication dosages and C. Liver failure
factors that influence medication metabolism with a group E. Concurrent use of medication the same pathway metabolizes
of nurses at an in-service presentation. Which of the
following factors should the educator include as a reason C. Liver failure decreases metabolism and thus increases the concentration of a
to administer lower medication dosages? (Select all that medication. This requires decreasing the dosage.
apply.)
E. When the same pathway metabolizes two medications, they compete for
A. Increased renal secretion metabolism, thereby increasing the concentration of one or both medications. This
B. Increased medication-metabolizing enzymes requires decreasing the dosage of one or both
C. Liver failure
D. Peripheral vascular disease
E. Concurrent use of medication the same pathway
metabolizes
A nurse is preparing to administer eye drops to a client. B. Ask the client to look up at the ceiling.
Which of the following actions should the nurse take? D. Drop the medication into the center of the client's conjunctival sac.
(Select all that apply.) E. Instruct the client to close her eye gently after instillation
A. Have the client lie on her side. (B. The client should look upward to keep the drops from falling onto her cornea.
B. Ask the client to look up at the ceiling. D. The nurse should drop the medication into the
C. Tell the client to blink when the drops enter her eye. center of the conjunctival sac to promote distribution.
D. Drop the medication into the center of the client's E. The client should close her eye gently to promote distribution of the medication)
conjunctival sac.
E. Instruct the client to close her eye gently after instillation
A nurse is completing discharge teaching for a client who C. "I will apply the patch to an area of skin with no hair."
has a new prescription for transdermal patches. Which of
the following statements should the nurse identify as an (The client should apply the patch to a hairless area of skin to promote absorption of
indication that the client understands the instructions? the medication.)
A. "I will clean the site with an alcohol swab before I apply
the patch."
B. "I will rotate the application sites weekly."
C. "I will apply the patch to an area of skin with no hair."
D. "I will place the new patch on the site of the old patch.
A nurse reviewing a client's medical record notes a new A. Obtain a blood specimen immediately prior to administering the next dose of
prescription for verifying the trough level of the client's medication.
medication. Which of the following actions should the
nurse take? (To verify trough levels of a medication, the nurse should obtain a blood specimen
immediately before administering the next dose of medication.)
A. Obtain a blood specimen immediately prior to
administering the next dose of medication.
B. Verify that the client has been taking the medication for
24 hr before obtaining a blood specimen.
C. Ask the client to provide a urine specimen after the next
dose of medication.
D. Administer the medication,and obtain a blood specimen
30 min late
,A nurse is preparing a client's medications. Which of the A. Maintain skill competency.
following actions should the nurse take in following legal C. Monitor for adverse effects.
practice guidelines? (Select all that apply.) D. Safeguard medications.
A. Maintain skill competency. (A.maintaining skill competency and using appropriate administration techniques
B. Determine the dosage. are legal responsibilities of the nurse
C. Monitor for adverse effects.
D. Safeguard medications. C. A nurse is legally responsible for monitoring for side and adverse effects of
E. Identify the client's diagnosis medication
D. Safeguarding of medications, such as controlled substances, is a legal
responsibility of the nurse)
A nurse reviewing a client's health record notes a new C. Routine
prescription for Lisinopril 10 mg PO once every day. The
nurse should identify this as which of the following types of (A routine or standard prescription identifies medications to give on a regular
prescription? schedule with or without a termination date or a specific number of doses. The
nurse will administer
A. Single this medication every day until the provider discontinues it.)
B. Stat
C. Routine
D. Standing
A nurse is reviewing a new prescription for Ondansetron 4 D. Frequency
mg PO PRN for nausea and vomiting for a client who has
Hyperemesis Gravidarum. The nurse should clarify which (This prescription does not include the time or frequency of medication
of the following parts of the prescription with the provider? administration. The nurse must clarify this with the prescribing provide)
A. Name
B. Dosage
C. Route
D. Frequency
A nurse is admitting a client and completing a A. Use of herbal teas
preassessment before administering medications. Which C. Current health status
of the following data should the nurse include in the E. Food allergies
preassessment? (Select all that apply.)
(A. The nurse should inquire about the client's use of herbal products, which often
A. Use of herbal teas contain caffeine, prior to medication administration because caffeine can affect
B. Daily fluid intake medication biotransformation
C. Current health status
D. Previous surgical history C. The nurse should review the client's current health status because new
E. Food allergies prescriptions can cause alterations in current health status
E. The nurse should inquire about food allergies during the preassessment to
identify any potential reactions or interactions)
A nurse orienting a newly licensed nurse is reviewing the B. "Another nurse should listen to the phone call."
procedure for taking a telephone prescription. Which of the
following statements should the nurse identify as an (A second nurse should listen to a telephone prescription to prevent errors in
indication that the newly licensed nurse understands the communication.)
process?
A. "A second nurse enters the prescription into the client's
medical record."
B. "Another nurse should listen to the phone call."
C. "The provider can clarify the prescription when he signs
the health record."
D. "I should omit the 'read back' if this is a one‑time
prescription
A nurse is preparing to administer vancomycin 1 g by 22
intermittent IV bolus. Available is vancomycin 1 g in 100
mL of dextrose 5% in water (D5W) to infuse over 45 min.
The drop factor of the manual IV tubing is 10 gtt/mL. The
nurse should adjust the manual IV infusion to deliver how
many gtt/min? (Round the answer to the nearest whole
number. Do not use a trailing zero.
, A nurse is preparing to administer clindamycin 200 mg by 200
intermittent IV bolus. The amount available is clindamycin
injection 200 mg in 100 mL 0.9% sodium chloride (0.9%
NaCl) to infuse over 30 min. The nurse should set the IV
pump to deliver how many mL/hr? (Round
the answer to the nearest whole number. Do not use a
trailing zero.
A nurse is preparing to administer furosemide 80 mg PO 8
daily. The amount available is furosemide oral
solution 10 mg/1 mL. how many mL should the nurse
administer? (Round the answer to the nearest whole
number. Do not use a trailing zero.)
A nurse is preparing to administer Haloperidol 2 mg PO 2
every 12 hr. The amount available is haloperidol 1
mg/tablet. how many tablets should the nurse administer?
(Round the answer to the nearest whole number. Do not
use a trailing zero.
A nurse is preparing to administer Amoxicillin 20 mg/kg/day 4
PO to divide equally every 12 hr to a preschooler who
weighs 44 lb. The amount available is amoxicillin
suspension 250 mg/5 mL. how many mL should the nurse
administer per dose? (Round the answer to the nearest
whole number. Do not use a trailing zero.)
A nurse is preparing to administer heparin 15,000 units 0.8
subcutaneously every 12 hr. The amount available is
heparin injection 20,000 units/mL. How many mL should
the nurse administer per dose? (Round the answer to the
nearest tenth. Do not use a trailing zero.
A nurse is preparing to administer acetaminophen 650 mg 6.5
PO every 6 hr PRN for pain. The amount available is
acetaminophen liquid 500 mg/5 mL.
how many mL should
the nurse administer per dose? (Round the answer to the
nearest tenth. Use a leading zero if it applies. Do not use a
trailing zero.
A nurse is preparing to administer dextrose 5% in water 125
(D5W) 750 mL IV to infuse over 6 hr. The nurse should set
the IV pump to
deliver how many mL/hr? (Round the answer to the
nearest whole number. Do not use a trailing zero.
A nurse is assessing a client's IV infusion site. Which of C. Erythema
the following findings should the nurse identify as an E. Pain
indication of phlebitis? (Select all that apply.)
(C. Erythema at the insertion site is a manifestation of phlebitis.
A. Pallor E.Pain at the insertion site is a manifestation of phlebitis.)
B. Dampness
C. Erythema
D. Coolness
E. Pain
A nurse manager is reviewing the facility's policies for IV D. Avoiding reinserting the needle into an IV catheter
therapy with the members of his team. The nurse manager
should remind the team that which of the following (The nurse manager should remind the members of the team to avoid reinserting
techniques helps minimize the risk of catheter embolism? the stylet needle into an IV catheter. This action can result in severing the end of the
catheter and consequently cause a catheter embolism)
A. Performing hand hygiene before and after IV insertion
B. Rotating IV sites at least every 72 hr
C. Minimizing tourniquet time
D. Avoiding reinserting the needle into an IV catheter
Questions & 100% Verified Answers with Rationales |
Comprehensive Pharmacology Exam Review |
2026–2027
,A provider prescribes phenobarbital for a client who has a A. One
seizure disorder. The medication has a long half-life of 4
days. How many times per day should the nurse expect to (Medications with long half-lives remain at their therapeutic levels between doses
administer this medication? for long periods of time. The nurse should expect to administer this medication once
a day.)
A. One
B. Two
C. Three
D. Four
A staff educator is reviewing medication dosages and C. Liver failure
factors that influence medication metabolism with a group E. Concurrent use of medication the same pathway metabolizes
of nurses at an in-service presentation. Which of the
following factors should the educator include as a reason C. Liver failure decreases metabolism and thus increases the concentration of a
to administer lower medication dosages? (Select all that medication. This requires decreasing the dosage.
apply.)
E. When the same pathway metabolizes two medications, they compete for
A. Increased renal secretion metabolism, thereby increasing the concentration of one or both medications. This
B. Increased medication-metabolizing enzymes requires decreasing the dosage of one or both
C. Liver failure
D. Peripheral vascular disease
E. Concurrent use of medication the same pathway
metabolizes
A nurse is preparing to administer eye drops to a client. B. Ask the client to look up at the ceiling.
Which of the following actions should the nurse take? D. Drop the medication into the center of the client's conjunctival sac.
(Select all that apply.) E. Instruct the client to close her eye gently after instillation
A. Have the client lie on her side. (B. The client should look upward to keep the drops from falling onto her cornea.
B. Ask the client to look up at the ceiling. D. The nurse should drop the medication into the
C. Tell the client to blink when the drops enter her eye. center of the conjunctival sac to promote distribution.
D. Drop the medication into the center of the client's E. The client should close her eye gently to promote distribution of the medication)
conjunctival sac.
E. Instruct the client to close her eye gently after instillation
A nurse is completing discharge teaching for a client who C. "I will apply the patch to an area of skin with no hair."
has a new prescription for transdermal patches. Which of
the following statements should the nurse identify as an (The client should apply the patch to a hairless area of skin to promote absorption of
indication that the client understands the instructions? the medication.)
A. "I will clean the site with an alcohol swab before I apply
the patch."
B. "I will rotate the application sites weekly."
C. "I will apply the patch to an area of skin with no hair."
D. "I will place the new patch on the site of the old patch.
A nurse reviewing a client's medical record notes a new A. Obtain a blood specimen immediately prior to administering the next dose of
prescription for verifying the trough level of the client's medication.
medication. Which of the following actions should the
nurse take? (To verify trough levels of a medication, the nurse should obtain a blood specimen
immediately before administering the next dose of medication.)
A. Obtain a blood specimen immediately prior to
administering the next dose of medication.
B. Verify that the client has been taking the medication for
24 hr before obtaining a blood specimen.
C. Ask the client to provide a urine specimen after the next
dose of medication.
D. Administer the medication,and obtain a blood specimen
30 min late
,A nurse is preparing a client's medications. Which of the A. Maintain skill competency.
following actions should the nurse take in following legal C. Monitor for adverse effects.
practice guidelines? (Select all that apply.) D. Safeguard medications.
A. Maintain skill competency. (A.maintaining skill competency and using appropriate administration techniques
B. Determine the dosage. are legal responsibilities of the nurse
C. Monitor for adverse effects.
D. Safeguard medications. C. A nurse is legally responsible for monitoring for side and adverse effects of
E. Identify the client's diagnosis medication
D. Safeguarding of medications, such as controlled substances, is a legal
responsibility of the nurse)
A nurse reviewing a client's health record notes a new C. Routine
prescription for Lisinopril 10 mg PO once every day. The
nurse should identify this as which of the following types of (A routine or standard prescription identifies medications to give on a regular
prescription? schedule with or without a termination date or a specific number of doses. The
nurse will administer
A. Single this medication every day until the provider discontinues it.)
B. Stat
C. Routine
D. Standing
A nurse is reviewing a new prescription for Ondansetron 4 D. Frequency
mg PO PRN for nausea and vomiting for a client who has
Hyperemesis Gravidarum. The nurse should clarify which (This prescription does not include the time or frequency of medication
of the following parts of the prescription with the provider? administration. The nurse must clarify this with the prescribing provide)
A. Name
B. Dosage
C. Route
D. Frequency
A nurse is admitting a client and completing a A. Use of herbal teas
preassessment before administering medications. Which C. Current health status
of the following data should the nurse include in the E. Food allergies
preassessment? (Select all that apply.)
(A. The nurse should inquire about the client's use of herbal products, which often
A. Use of herbal teas contain caffeine, prior to medication administration because caffeine can affect
B. Daily fluid intake medication biotransformation
C. Current health status
D. Previous surgical history C. The nurse should review the client's current health status because new
E. Food allergies prescriptions can cause alterations in current health status
E. The nurse should inquire about food allergies during the preassessment to
identify any potential reactions or interactions)
A nurse orienting a newly licensed nurse is reviewing the B. "Another nurse should listen to the phone call."
procedure for taking a telephone prescription. Which of the
following statements should the nurse identify as an (A second nurse should listen to a telephone prescription to prevent errors in
indication that the newly licensed nurse understands the communication.)
process?
A. "A second nurse enters the prescription into the client's
medical record."
B. "Another nurse should listen to the phone call."
C. "The provider can clarify the prescription when he signs
the health record."
D. "I should omit the 'read back' if this is a one‑time
prescription
A nurse is preparing to administer vancomycin 1 g by 22
intermittent IV bolus. Available is vancomycin 1 g in 100
mL of dextrose 5% in water (D5W) to infuse over 45 min.
The drop factor of the manual IV tubing is 10 gtt/mL. The
nurse should adjust the manual IV infusion to deliver how
many gtt/min? (Round the answer to the nearest whole
number. Do not use a trailing zero.
, A nurse is preparing to administer clindamycin 200 mg by 200
intermittent IV bolus. The amount available is clindamycin
injection 200 mg in 100 mL 0.9% sodium chloride (0.9%
NaCl) to infuse over 30 min. The nurse should set the IV
pump to deliver how many mL/hr? (Round
the answer to the nearest whole number. Do not use a
trailing zero.
A nurse is preparing to administer furosemide 80 mg PO 8
daily. The amount available is furosemide oral
solution 10 mg/1 mL. how many mL should the nurse
administer? (Round the answer to the nearest whole
number. Do not use a trailing zero.)
A nurse is preparing to administer Haloperidol 2 mg PO 2
every 12 hr. The amount available is haloperidol 1
mg/tablet. how many tablets should the nurse administer?
(Round the answer to the nearest whole number. Do not
use a trailing zero.
A nurse is preparing to administer Amoxicillin 20 mg/kg/day 4
PO to divide equally every 12 hr to a preschooler who
weighs 44 lb. The amount available is amoxicillin
suspension 250 mg/5 mL. how many mL should the nurse
administer per dose? (Round the answer to the nearest
whole number. Do not use a trailing zero.)
A nurse is preparing to administer heparin 15,000 units 0.8
subcutaneously every 12 hr. The amount available is
heparin injection 20,000 units/mL. How many mL should
the nurse administer per dose? (Round the answer to the
nearest tenth. Do not use a trailing zero.
A nurse is preparing to administer acetaminophen 650 mg 6.5
PO every 6 hr PRN for pain. The amount available is
acetaminophen liquid 500 mg/5 mL.
how many mL should
the nurse administer per dose? (Round the answer to the
nearest tenth. Use a leading zero if it applies. Do not use a
trailing zero.
A nurse is preparing to administer dextrose 5% in water 125
(D5W) 750 mL IV to infuse over 6 hr. The nurse should set
the IV pump to
deliver how many mL/hr? (Round the answer to the
nearest whole number. Do not use a trailing zero.
A nurse is assessing a client's IV infusion site. Which of C. Erythema
the following findings should the nurse identify as an E. Pain
indication of phlebitis? (Select all that apply.)
(C. Erythema at the insertion site is a manifestation of phlebitis.
A. Pallor E.Pain at the insertion site is a manifestation of phlebitis.)
B. Dampness
C. Erythema
D. Coolness
E. Pain
A nurse manager is reviewing the facility's policies for IV D. Avoiding reinserting the needle into an IV catheter
therapy with the members of his team. The nurse manager
should remind the team that which of the following (The nurse manager should remind the members of the team to avoid reinserting
techniques helps minimize the risk of catheter embolism? the stylet needle into an IV catheter. This action can result in severing the end of the
catheter and consequently cause a catheter embolism)
A. Performing hand hygiene before and after IV insertion
B. Rotating IV sites at least every 72 hr
C. Minimizing tourniquet time
D. Avoiding reinserting the needle into an IV catheter
