PREP BUNDLE 2026-2027 QUESTIONS,
ANSWERS & RATIONALES
Master the ShiftKey LPN/LVN Medical-Surgical Nursing
Assessment with this newly released, comprehensive practice
exam bank [2026/2027]. Each multiple-choice question features
highlighted correct answers and premium, high-yield clinical
rationales designed to guarantee an A+ grade on your first
attempt. Perfect for nursing students and working professionals
aiming to secure top-tier placements through quick and efficient
exam preparation.
Q1. Infection Control: C. difficile
A nurse is caring for a client with confirmed
Clostridioides difficile (C. diff). Which action is
mandatory when exiting the client's room?
A) Use an alcohol-based hand rub for 20 seconds.
B) Wash hands thoroughly with antimicrobial soap
and water.
C) Rinse hands with warm water only.
D) Double-glove before using alcohol-based hand
sanitizer.
Rationale: C. difficile is a spore-forming
bacterium. Alcohol-based rubs cannot penetrate
its protective spore shell. Mechanical friction
with soap and water is required to physically
remove and rinse the spores from the skin.
,Q2. Pressure Injury Staging: Sacral Ulcer
During a skin assessment, the nurse notes an open,
shallow ulcer on the client's sacrum with a red-pink
wound bed. There is no slough or bruising present.
How should this wound be staged?
A) Stage 1
B) Stage 2
C) Stage 3
D) Unstageable
Rationale: Stage 2 pressure injuries involve
partial-thickness skin loss with exposed dermis.
The wound bed is viable, pink or red, and moist,
presenting as a shallow open ulcer or an
intact/ruptured serum-filled blister.
Q3. Fluid and Electrolytes: Loop Diuretics
A client taking furosemide (Lasix) 40 mg daily
reports severe muscle weakness and a "fluttering"
sensation in the chest. Which lab value should the
nurse review immediately?
A) Sodium 138 mEq/L
B) Potassium 2.9 mEq/L
C) Calcium 9.2 mg/dL
D) Magnesium 2.0 mEq/L
Rationale: Furosemide is a potassium-wasting
loop diuretic. Hypokalemia (potassium < 3.5
,mEq/L) causes cardiac dysrhythmias,
palpitations, and generalized muscle weakness.
Q4. Pharmacology: IV Drip Rate Calculation
An IV infusion of 1,000 mL Normal Saline is ordered
to run over 8 hours. The drop factor is 15 gtt/mL.
What is the correct infusion rate in drops per minute
(gtt/min)?
A) 21 gtt/min
B) 31 gtt/min
C) 42 gtt/min
D) 125 gtt/min
Rationale: Formula: (Total Volume in mL × Drop
Factor) ÷ Total Time in Minutes. (1,000 mL × 15
gtt) ÷ 480 minutes = 31.25, which rounds down to
31 gtt/min.
Q5. Respiratory Care: Oxygen Toxicity & COPD
A client with severe Chronic Obstruction Pulmonary
Disease (COPD) is receiving oxygen via nasal
cannula at 5 L/min. The nurse notes the client is
increasingly lethargic and has a respiratory rate of 9
breaths/minute. What is the likely cause?
A) Suppression of the hypoxic drive
B) Acute pulmonary embolism
C) Anxiety-induced hyperventilation
, D) Worsening metabolic acidosis
Rationale: In chronic hypercapnia (COPD), the
central chemoreceptors become insensitive to
high CO2 levels, shifting the stimulus to breathe
to low oxygen levels (hypoxic drive). Excessive
oxygen delivery eliminates this drive, causing
hypoventilation.
Q6. Mobility: Cane Ambulation
The nurse is reinforcing teaching with a client who
has right-sided weakness on how to ambulate with a
single-ended cane. Which instruction is correct?
A) Hold the cane in the right hand and move the left
leg first.
B) Hold the cane in the right hand and move the
right leg first.
C) Hold the cane in the left hand and advance the
cane with the right leg.
D) Hold the cane in the left hand and advance the
cane with the left leg.
Rationale: A cane should always be held on the
unaffected (strong) side to widen the base of
support and reduce stress on the affected limb.
The cane is advanced simultaneously with the
affected (weak) leg.
Q7. Cardiovascular: Blood Transfusion Reaction