CARN-AP |Actual Exam Test Questions With Well Elaborated Solutions

CARN-AP |Actual Exam Test Questions With Well Elaborated Solutions A 57-year-old man with a longstanding history of alcohol use presents with confusion, disorientation, and gait imbalance. Other than disorientation, bilateral paresis of conjugate gaze is noted. CT head is negative. Which vitamin deficiency is most likely? - ANSWER -Thiamine (B1) What medication used in AUD inhibits ALDH? - ANSWER -Disulfiram Disulfiram action causes an excess of what enzyme? This enzyme has a vasodilatory effect that causes: - ANSWER -Acetaldehyde tachycardia and hypotension. 4 NTs associated with drinking are - ANSWER -Glutamate GABA Dopamine Endogenous opioids When alcohol is consumed there is a release of ___________ ________, then _______ ,which makes the drinker feel good. AT THE SAME TIME alcohol has an effect on ______ receptors; they are are increased (sedation effect) OVERTIME the brain responds to an excess and increase of alcohol by upregulating ________ receptors to compensate for the increase in GABA - ANSWER -endogenous opioids dopamine GABA glutamate Alcohol withdrawal symptoms will occur when there is excess ________ activity in relevance to GABA - ANSWER -glutamate Minor alcohol withdrawal occurs within _______ after their last drink - ANSWER -36 Disulfiram has a _____ half life; reaction could occur 1-2 weeks after last dose - ANSWER -long Acamprosate is a _______ receptor modulator Dosage: 2x333mg PO tab TID Indication: - ANSWER -glutamate Those individuals who are abstinent from alcohol at initiation of treatment Naltrexone is an opioid receptor _______ - ANSWER -antagonist _____ is the most suitable drug for patients with mild opioid use disorder. - ANSWER -Naltrexone Naltrexone is the most suitable drug for patients with _____ opioid use disorder. - ANSWER -mild Which AUD drug will cause opioid withdrawal symptoms in patients who are physically dependent on opioids? Person must not had taken long acting opioids how many days prior to starting? Person must not had taken short acting opioids how many days prior to starting? Confirm abstinence with what 2 things?: - ANSWER -Naltrexone 10-14 day atleast7 Urine drug test & Naltrexone Challenge _________-based treatment is not recommended for patients with moderate to severe opioid use disorder. - ANSWER -Abstinence Abstinence from Alcohol is a requirement prior to starting Naltrexone T or F - ANSWER -False ER dose of Naltrexone is called what? How often is it administered? - ANSWER -Vivitrol q month Larger doses of high dose opioids may be needed to override Naltrexone blockade T or F - ANSWER -True Gabapentin shows to help with post acute withdrawal symptoms like _______ and _______ Shown improvement when added with _______in the first __ weeks - ANSWER anxiety, insomnia naltrexone 6 Topiramate is traditionally used for what? In clinical trials its use has been associated with an improvement in what 2 things? - ANSWER -anticonvulsant and migraine prophylaxis Binge drinking Which MAT for AUD should the clinician be mindful of when the patient has elevated LFTs? - ANSWER -Naltrexone Individuals with mild liver impairment can still use Naltrexone T or F - ANSWER -True someone who can go several days w/o drinking MAT for AUD is indicated T or F - ANSWER -false Laura, if encountering an AUD pt, ask how long in the past few months have you gone without drinking? have you gone more than 3 days without drinking? if so do you have withdrawal symptoms? - ANSWER - Opioid withdrawal