Adv. Pharm NURS 8024 Week 1 | Questions with 100% Verified Answers |
Latest Update
Question: Pharmacokinetics
Answer:
what the body does to the drug
Question: Pharmacodynamics
Answer:
what the drug does to the body
Question: Toxicology
Answer:
The undesirable effects of chemicals on living systems
Question: Pharmacotherapeutics
Answer:
dynamic that achieves the desired therapeutic effect of the drug without causing other undesirable effects
Question: Legend drugs
Answer:
another name for prescription drugs
Question: Pharmacogenomics
Answer:
the study of genetically determined variations in the response to drugs
Question: Pharmacologic Agonist
Answer:
agent binds to and activates the receptor - directly or indirectly causing an effect, full or partial agonists
Question: Pharmacological Antagonist
Answer:
Agent binds to receptor-completes with other molecules and prevents binding by other molecules-it
inhibits other molecules from binding
Question: Pro-drug
Answer:
, An inactive percursor chemical-must be abosorbed and distributed and converted to the active form of
the drug by biologic processes.
Question: What is ADME?
Answer:
Absorption Distribution Metabolism Elimination
Question: Absorption
Answer:
entry of pharmacologic agent into plasma
Question: Distribution
Answer:
agent leaves the bloodstream and distributes to interstitial and intracellular fluids
Question: Metablosim
Answer:
chemical processes that occur to make the drug useful in the bloodstream--done by the liver, kidney, or
other tissue
Question: Ellimination
Answer:
Leaving the body-via urine, bile, feces, lungs, sweat, breast milk
Question: 2 Major Administration Routes
Answer:
1. Enteral -most common, easy, cheap-BUT drug absorption pathways can be complicated
2. Parenteral-IV, fast, more expensive, once in-cannot get back
Question: Enteral drug administration
Answer:
oral, sublingual, rectal drug absorption pathways complicated **First-pass metabolism can limit the
amount of drug that enters systemic circulation influenced by food and other drugs
Question: What is first pass metabolism?
Answer:
The concentration of drug is greatly reduced BEFORE reaching systemic circulation. This mainly
involves liver enzymes, but also includes gastric enzymes, gut wall enzymes, and bacterial enzymes.
Latest Update
Question: Pharmacokinetics
Answer:
what the body does to the drug
Question: Pharmacodynamics
Answer:
what the drug does to the body
Question: Toxicology
Answer:
The undesirable effects of chemicals on living systems
Question: Pharmacotherapeutics
Answer:
dynamic that achieves the desired therapeutic effect of the drug without causing other undesirable effects
Question: Legend drugs
Answer:
another name for prescription drugs
Question: Pharmacogenomics
Answer:
the study of genetically determined variations in the response to drugs
Question: Pharmacologic Agonist
Answer:
agent binds to and activates the receptor - directly or indirectly causing an effect, full or partial agonists
Question: Pharmacological Antagonist
Answer:
Agent binds to receptor-completes with other molecules and prevents binding by other molecules-it
inhibits other molecules from binding
Question: Pro-drug
Answer:
, An inactive percursor chemical-must be abosorbed and distributed and converted to the active form of
the drug by biologic processes.
Question: What is ADME?
Answer:
Absorption Distribution Metabolism Elimination
Question: Absorption
Answer:
entry of pharmacologic agent into plasma
Question: Distribution
Answer:
agent leaves the bloodstream and distributes to interstitial and intracellular fluids
Question: Metablosim
Answer:
chemical processes that occur to make the drug useful in the bloodstream--done by the liver, kidney, or
other tissue
Question: Ellimination
Answer:
Leaving the body-via urine, bile, feces, lungs, sweat, breast milk
Question: 2 Major Administration Routes
Answer:
1. Enteral -most common, easy, cheap-BUT drug absorption pathways can be complicated
2. Parenteral-IV, fast, more expensive, once in-cannot get back
Question: Enteral drug administration
Answer:
oral, sublingual, rectal drug absorption pathways complicated **First-pass metabolism can limit the
amount of drug that enters systemic circulation influenced by food and other drugs
Question: What is first pass metabolism?
Answer:
The concentration of drug is greatly reduced BEFORE reaching systemic circulation. This mainly
involves liver enzymes, but also includes gastric enzymes, gut wall enzymes, and bacterial enzymes.
