BARKLEY EVIDENCE-BASED PRACTICE
PRACTICE QUESTIONS Comprehensive 150-
Question Practice Examination – New
Edition
INTRODUCTION
The Barkley Evidence-Based Practice Practice Questions is a
comprehensive, standardized practice examination designed to
evaluate the evidence-based practice (EBP) knowledge, research
appraisal skills, and clinical decision-making required for safe,
effective advanced practice nursing. This examination mirrors
the EBP content tested on the AANPCB, ANCC, and PNCB
certification exams and emphasizes the integration of best
evidence, clinical expertise, and patient preferences
required for independent practice.
This examination is structured around the core EBP domains:
• Foundations of Evidence-Based Practice
• Research Designs and Levels of Evidence
• Critical Appraisal of Evidence
• Clinical Practice Guidelines
• Implementation and Translation of Evidence
• Ethical Considerations in Research
• Quality Improvement and Outcomes Evaluation
• Nursing Theory and Research Utilization
Each of the 150 questions is presented in a clinical scenario-
based format, requiring the advanced practice nurse to apply
, the EBP process (Ask, Acquire, Appraise, Apply, Assess) and
evidence-based clinical guidelines .
Answer Format:
• Correct answers and detailed explanations are presented in
italics.
• Rationales and clinical reasoning are presented in bold.
This examination is intended for advanced practice nursing
students preparing for certification, practicing APRNs seeking
continuing education, and educators developing
comprehensive assessment tools.
TABLE OF CONTENTS
Section Content Area Question Ra
I Foundations of Evidence-Based Practice 1–25
II Research Designs and Levels of Evidence 26–50
III Critical Appraisal of Evidence 51–75
IV Clinical Practice Guidelines 76–95
V Implementation and Translation of Evidence 96–115
VI Ethical Considerations in Research 116–130
VII Quality Improvement and Outcomes Evaluation 131–150
Answer Key & Rationales 1–150
,SECTION I: FOUNDATIONS OF EVIDENCE-BASED PRACTICE
(Questions 1–25)
Question 1
Which of the following are parts of evidence-based practice?
A. Clinician
B. Patient
C. Evidence
D. All of the above
Answer: D
Evidence-based practice integrates the clinician's expertise, the
patient's values and preferences, and the best available evidence
.
Rationale: The clinician (A) provides clinical expertise and
judgment. The patient (B) brings values, preferences, and
unique circumstances. Evidence (C) provides the best
available research. All three components are essential to
EBP .
Question 2
Which component of nursing is the key to building evidence-
based practice?
A. Theory
B. Process
C. Research
D. Education
, Answer: C
Research validates and expands nursing knowledge, forming the
foundation for evidence-based practice .
Rationale: Theory (A) and process (B) are tools used within
EBP but are not the key building component. Education (D)
is important but not the foundation. Research (C) generates
the evidence that drives EBP .
Question 3
Nursing research should be utilized by:
A. Only nurse researchers
B. Only advanced practice nurses
C. Nurses at all levels of practice
D. Only nurse educators
Answer: C
Nursing research should be utilized by nurses at all levels of
practice to inform clinical decision-making and improve patient
outcomes .
Rationale: Restricting research utilization to nurse
researchers (A), advanced practice nurses (B), or nurse
educators (D) excludes bedside nurses who are essential to
implementing evidence at the point of care. All nurses (C)
should utilize research .
PRACTICE QUESTIONS Comprehensive 150-
Question Practice Examination – New
Edition
INTRODUCTION
The Barkley Evidence-Based Practice Practice Questions is a
comprehensive, standardized practice examination designed to
evaluate the evidence-based practice (EBP) knowledge, research
appraisal skills, and clinical decision-making required for safe,
effective advanced practice nursing. This examination mirrors
the EBP content tested on the AANPCB, ANCC, and PNCB
certification exams and emphasizes the integration of best
evidence, clinical expertise, and patient preferences
required for independent practice.
This examination is structured around the core EBP domains:
• Foundations of Evidence-Based Practice
• Research Designs and Levels of Evidence
• Critical Appraisal of Evidence
• Clinical Practice Guidelines
• Implementation and Translation of Evidence
• Ethical Considerations in Research
• Quality Improvement and Outcomes Evaluation
• Nursing Theory and Research Utilization
Each of the 150 questions is presented in a clinical scenario-
based format, requiring the advanced practice nurse to apply
, the EBP process (Ask, Acquire, Appraise, Apply, Assess) and
evidence-based clinical guidelines .
Answer Format:
• Correct answers and detailed explanations are presented in
italics.
• Rationales and clinical reasoning are presented in bold.
This examination is intended for advanced practice nursing
students preparing for certification, practicing APRNs seeking
continuing education, and educators developing
comprehensive assessment tools.
TABLE OF CONTENTS
Section Content Area Question Ra
I Foundations of Evidence-Based Practice 1–25
II Research Designs and Levels of Evidence 26–50
III Critical Appraisal of Evidence 51–75
IV Clinical Practice Guidelines 76–95
V Implementation and Translation of Evidence 96–115
VI Ethical Considerations in Research 116–130
VII Quality Improvement and Outcomes Evaluation 131–150
Answer Key & Rationales 1–150
,SECTION I: FOUNDATIONS OF EVIDENCE-BASED PRACTICE
(Questions 1–25)
Question 1
Which of the following are parts of evidence-based practice?
A. Clinician
B. Patient
C. Evidence
D. All of the above
Answer: D
Evidence-based practice integrates the clinician's expertise, the
patient's values and preferences, and the best available evidence
.
Rationale: The clinician (A) provides clinical expertise and
judgment. The patient (B) brings values, preferences, and
unique circumstances. Evidence (C) provides the best
available research. All three components are essential to
EBP .
Question 2
Which component of nursing is the key to building evidence-
based practice?
A. Theory
B. Process
C. Research
D. Education
, Answer: C
Research validates and expands nursing knowledge, forming the
foundation for evidence-based practice .
Rationale: Theory (A) and process (B) are tools used within
EBP but are not the key building component. Education (D)
is important but not the foundation. Research (C) generates
the evidence that drives EBP .
Question 3
Nursing research should be utilized by:
A. Only nurse researchers
B. Only advanced practice nurses
C. Nurses at all levels of practice
D. Only nurse educators
Answer: C
Nursing research should be utilized by nurses at all levels of
practice to inform clinical decision-making and improve patient
outcomes .
Rationale: Restricting research utilization to nurse
researchers (A), advanced practice nurses (B), or nurse
educators (D) excludes bedside nurses who are essential to
implementing evidence at the point of care. All nurses (C)
should utilize research .
