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NURS 615- Pharmacology: Gastroesophageal Reflux | Questions with 100% Verified Answers | Latest Update

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NURS 615- Pharmacology: Gastroesophageal Reflux | Questions with 100% Verified Answers | Latest Update

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NURS 615- Pharmacology: Gastroesophageal Reflux | Questions with 100%
Verified Answers | Latest Update
Question: GERD is the movement of stomach acid/gastric contents upward into the esophagus.
Answer:
Which statements are correct about GERD?

Question: PUD involves erosion of the GI mucosal layer
Answer:
Which statements are correct about PUD?

Question: antiulcer drugs tumor necrosis factor-alpha (TNF-alpha) blocker drugs adsorbent, antiflatulent,
and digestive drugs antidiarrheal and laxative drugs obesity drugs antiemetic drugs
Answer:
Classes of drugs used to improve GI function include:

Question: PPIs are a class of drugs that reduce stomach acid production by blocking the proton pump in
the stomach lining.
Answer:
What are Proton Pump Inhibitors (PPIs)?

Question: Common adverse effects include headache, diarrhea, constipation, and nausea.
Answer:
What are common adverse effects of Proton Pump Inhibitors?

Question: Serious adverse effects may include increased risk of Clostridium difficile infection, bone
fractures, and kidney disease.
Answer:
What serious adverse effects can occur with long-term use of PPIs?

Question: Contraindications include known hypersensitivity to the drug and severe renal impairment.
Answer:
What are contraindications for using Histamine-2 Receptor Antagonists?

Question: Common adverse effects include constipation, diarrhea, and electrolyte imbalances.
Answer:
What are common adverse effects of Antacids?

, Question: They are used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic
ulcers.
Answer:
What are the clinical uses of Histamine-2 Receptor Antagonists?

Question: Cimetidine (Tagamet) Ranitidine (Zantac) Famotidine (Pepcid) Nizatidine (Axid)
Answer:
What are some common H2 receptor antagonists?

Question: Blocks histamine2- receptors in stomach leading to decreased acid production (suppresses
volume & acidity of parietal cell secretions)
Answer:
What are the indications for H2 receptor antagonists?

Question: PPIs are used for treating GERD, peptic ulcers, and Zollinger- Ellison syndrome.
Answer:
What are the clinical uses for Proton Pump Inhibitors?

Question: PPIs suppress gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in
parietal cells, leading to decreased production of HCl.
Answer:
What is the mechanism of action of proton pump inhibitors (PPIs)?

Question: GI symptoms (nausea, abdominal pain, flatulence), dizziness, and drowsiness.
Answer:
What are common side effects of Proton Pump Inhibitors?

Question: Nutrient deficiencies (iron, magnesium, vitamin B12, calcium), increased risk of hip fractures,
chronic kidney disease, infections (e.g., Clostridioides difficile), and potential gastric cancer association
Answer:
What are Long-term side effects of Proton Pump Inhibitors?

Question: Contraindications include known hypersensitivity to PPIs and concurrent use of certain
medications that may interact.
Answer:
What are the contraindications for using Proton Pump Inhibitors?

Question: They reduce gastric acid secretion, promoting healing of peptic ulcers.

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