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FAMILY NURSE PRACTITIONER CLINICAL GUIDE STUDY GUIDE 2026/2027 | COMPLETE PRACTICE QUESTIONS, DETAILED ANSWERS AND COMPREHENSIVE FNP EXAM PREP

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FAMILY NURSE PRACTITIONER CLINICAL GUIDE STUDY GUIDE 2026/2027 | COMPLETE PRACTICE QUESTIONS, DETAILED ANSWERS AND COMPREHENSIVE FNP EXAM PREP

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Family Nurse Practitioner Clinical Guide
(FNP) – Exam Prep – 2025–2026 – Complete
Notes & Study Material

100 MCQAs for Revision



Cardiovascular Disorders

1. Hypertension Management

Description: A 58-year-old male with stage 2 hypertension and no comorbidities.

Keywords: hypertension, JNC 8, first-line therapy, thiazide

Q: Which medication is considered first-line therapy for this patient?
A. Lisinopril
B. Amlodipine
C. Hydrochlorothiazide ✅
D. Metoprolol




2. Heart Failure

Description: A 72-year-old female with HFrEF (EF 30%) and NYHA Class II symptoms.

Keywords: heart failure, HFrEF, beta-blocker, mortality

,Q: Which medication has been shown to reduce mortality in HFrEF?
A. Diltiazem
B. Carvedilol ✅
C. Verapamil
D. Amiodarone




3. Atrial Fibrillation

Description: A 65-year-old male with new-onset atrial fibrillation and CHA₂DS₂-VASc
score of 3.

Keywords: atrial fibrillation, anticoagulation, stroke risk, CHA₂DS₂-VASc

Q: What is the most appropriate anticoagulation therapy?
A. Aspirin 81 mg daily
B. Apixaban ✅
C. Clopidogrel
D. Ibuprofen




4. Acute Coronary Syndrome

Description: A 55-year-old male presents with crushing chest pain, diaphoresis, and ST
elevation on ECG.

Keywords: STEMI, acute coronary syndrome, reperfusion, aspirin

Q: What is the priority intervention?
A. Administer sublingual nitroglycerin

,B. Activate EMS and prepare for PCI ✅
C. Obtain chest X-ray
D. Start beta-blocker




5. Hyperlipidemia

Description: A 48-year-old female with LDL 190 mg/dL and family history of premature
CAD.

Keywords: hyperlipidemia, statin, ASCVD, LDL

Q: What is the recommended first-line pharmacotherapy?
A. Niacin
B. High-intensity statin ✅
C. Fibrate
D. Omega-3 fatty acids




Respiratory Disorders

6. Asthma

Description: A 24-year-old female with intermittent asthma symptoms twice weekly.

Keywords: asthma, SABA, GINA, controller therapy

Q: What is the preferred rescue medication?
A. Fluticasone
B. Albuterol ✅

, C. Montelukast
D. Prednisone




7. COPD

Description: A 68-year-old male smoker with COPD and FEV1 55% predicted.

Keywords: COPD, GOLD, LAMA, exacerbation

Q: Which class of inhaler is first-line maintenance therapy?
A. SABA
B. LAMA ✅
C. Inhaled corticosteroid alone
D. Oral corticosteroid




8. Pneumonia

Description: A 70-year-old female with CAP and CURB-65 score of 2.

Keywords: pneumonia, CAP, CURB-65, antibiotics

Q: What is the most appropriate disposition?
A. Outpatient with azithromycin
B. Hospital admission ✅
C. ICU admission
D. No treatment needed

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