Biochem Final Exam with question and
answer 100% correct
gluconeogenesis What is the name of the pathway that converts
noncarbohydate molecules into glucose?
glycolysis The Embden Meyerhof pathway is also known as ___.
obligate anaerobes What type of organism cannot survive in the presence of
oxygen?
UDP-glucose Which of the following intermediates is needed for the
conversion of galactose into glucose by reacting with
glactose 1-phosphate?
ATP Which of the following is an allosteric inhibitor of
phosphofructokinase?
NAD+ Which of the following must be regenerated for glycolysis to
proceed?
galactosemia Which of the following conditions results from genetic
deficiency of single transferase enzyme?
biotin This essential nutrient is required for the carboxylation of
pyruvate in humans
2 Glycolysis produces a net of ___ moles of ATP per 1 mole of
glucose.
AMP This is an allosteric inhibitor of gluconeogenesis
alpha-amylase Pancreatic ___ is the digestive enzyme primarily responsible for
the hydrolysis of dietary plant starch.
phosphofructokinase The key enzyme that regulates the pace of glycolysis is ___.
enediol The catalytic mechanism of the isomerization of a ketose into
an aldose proceeds through an ___ intermediate.
substrate-level phophorylation The formation of ATP is due to direct transfer of a phosphoryl
group and is called ___.
thiamine (B1) In alcoholic fermentation, the decarboxylation of pyruvate
requires a coenzyme that contains the vitamin ___.
, HIF-1 In the absence of oxygen,______increases the expression of
most glycolytic enzymes and the glucose transporters GLUT1
and GLUT3.
Cori The ___ cycle refers to the metabolic reactions by which
glucose is converted into lactate in skeletal muscle, and then
lactate converted back into glucose in the liver.
carboxylation The first step in gluconeogenesis is the____of pyruvate to form
oxaloacetate.
in its stable ring structure, glucose is unlikely Which of the following are reasons that glucose is a common
to nonezymatically glycosylate prtoeins. metabolic fuel used by living organisms?
also it is one of the fuels formed under
prebiotic conditions, thus available for
primitive biochemcial systems
GLUT5 What transporter is responsible for fructose uptake in the
intestine?
to trap glucose in the cell and to What is the purpose of phosphorylating glucose in cytosol?
destabalize glucose and facilitate the next
series of metabolic steps
glyceraldehyde-3-phosphate and What two 3-carbon molecules are generated by the cleavage
dihydroxyacetone phosphate of fructose-1,6-bisphosphate?
Binding of substrate causes a large What is a common mechanistic feature of kinases?
conformation change that results in cleft
closing.
fructose-2,6-bisphosphate A potent allosteric activator of liver phosphofructokinase is
____, which is produced from fructose-6-phosphate by PFK2.
reversible cleavage of F-1,6-BP to DHAP and What reaction is catalyzed by aldolase?
GAP
oxidation by NAD+ and formation of acyl- What is the function of glyceraldehyde 3-phosphate
phosphate dehydrogenase?
The thioester allows the two-step What is the function of a thioester intermediate such as the
reaction to be coupled so the second one formed from GAP?
reaction, the energetically unfavorable
phosphorylation, can proceed.
ATP synthesis when the phosphate donor is What is substrate level phosphorylation?
a substrate with high phosphoryl
transfer
potential
2,3-bisphosphoglycerate What is the additional metabolite that is required for the
conversion of 3-phosphoglycerate to 2-phosphoglycerate?
answer 100% correct
gluconeogenesis What is the name of the pathway that converts
noncarbohydate molecules into glucose?
glycolysis The Embden Meyerhof pathway is also known as ___.
obligate anaerobes What type of organism cannot survive in the presence of
oxygen?
UDP-glucose Which of the following intermediates is needed for the
conversion of galactose into glucose by reacting with
glactose 1-phosphate?
ATP Which of the following is an allosteric inhibitor of
phosphofructokinase?
NAD+ Which of the following must be regenerated for glycolysis to
proceed?
galactosemia Which of the following conditions results from genetic
deficiency of single transferase enzyme?
biotin This essential nutrient is required for the carboxylation of
pyruvate in humans
2 Glycolysis produces a net of ___ moles of ATP per 1 mole of
glucose.
AMP This is an allosteric inhibitor of gluconeogenesis
alpha-amylase Pancreatic ___ is the digestive enzyme primarily responsible for
the hydrolysis of dietary plant starch.
phosphofructokinase The key enzyme that regulates the pace of glycolysis is ___.
enediol The catalytic mechanism of the isomerization of a ketose into
an aldose proceeds through an ___ intermediate.
substrate-level phophorylation The formation of ATP is due to direct transfer of a phosphoryl
group and is called ___.
thiamine (B1) In alcoholic fermentation, the decarboxylation of pyruvate
requires a coenzyme that contains the vitamin ___.
, HIF-1 In the absence of oxygen,______increases the expression of
most glycolytic enzymes and the glucose transporters GLUT1
and GLUT3.
Cori The ___ cycle refers to the metabolic reactions by which
glucose is converted into lactate in skeletal muscle, and then
lactate converted back into glucose in the liver.
carboxylation The first step in gluconeogenesis is the____of pyruvate to form
oxaloacetate.
in its stable ring structure, glucose is unlikely Which of the following are reasons that glucose is a common
to nonezymatically glycosylate prtoeins. metabolic fuel used by living organisms?
also it is one of the fuels formed under
prebiotic conditions, thus available for
primitive biochemcial systems
GLUT5 What transporter is responsible for fructose uptake in the
intestine?
to trap glucose in the cell and to What is the purpose of phosphorylating glucose in cytosol?
destabalize glucose and facilitate the next
series of metabolic steps
glyceraldehyde-3-phosphate and What two 3-carbon molecules are generated by the cleavage
dihydroxyacetone phosphate of fructose-1,6-bisphosphate?
Binding of substrate causes a large What is a common mechanistic feature of kinases?
conformation change that results in cleft
closing.
fructose-2,6-bisphosphate A potent allosteric activator of liver phosphofructokinase is
____, which is produced from fructose-6-phosphate by PFK2.
reversible cleavage of F-1,6-BP to DHAP and What reaction is catalyzed by aldolase?
GAP
oxidation by NAD+ and formation of acyl- What is the function of glyceraldehyde 3-phosphate
phosphate dehydrogenase?
The thioester allows the two-step What is the function of a thioester intermediate such as the
reaction to be coupled so the second one formed from GAP?
reaction, the energetically unfavorable
phosphorylation, can proceed.
ATP synthesis when the phosphate donor is What is substrate level phosphorylation?
a substrate with high phosphoryl
transfer
potential
2,3-bisphosphoglycerate What is the additional metabolite that is required for the
conversion of 3-phosphoglycerate to 2-phosphoglycerate?
