CITI TRAINING QUESTIONS | FROM QUESTION TO
PERFECTION| STUDY WITH CONFIDENCE!
Course Code:
Course Title:
Programme:
Academic Year: 2026/2027.
Duration: 2 Hours.
Total Marks: 100.
Candidate Instructions:
1) Write your Registration Number on every answer booklet used.
2) Answer ALL questions in Section A and ANY TWO (2) questions in Section B.
3) Read each question carefully before answering.
4) Begin each question on a new page.
5) The marks for each question are indicated in brackets.
6) This paper consists of several printed pages, including this page.
7) Ensure your copy is complete before the examination begins.
8) Unauthorized materials and communication with other candidates are not permitted.
Turn Over.
APPHIA – Crafted with Care and Precision for Academic Excellence.
1
, If the PI does not agree with the IRE findings they can request: Answer: Review by the USG
Which of the following is a responsibility of the IRE? Answer: Notification within 30 days of
organizational review to the USG funding agency
For research to qualify as potential DURC, the PI and IRE must perform an initial assessment
on which of the following? Answer: Use of a listed agent or toxin that may result in one or
more of the seven experiments of concern
What organizations are required to have an IRE if DURC is being considered? Answer: Any
organization that receives money from the federal government
How often is IRE review required to determine if the research still falls under DURC or
enhanced measures are required? Answer: At least annually
Which of the following is accurate regarding the National Institute for Occupational Safety and
Health's (NIOSH) exposure limits for nanomaterials? Answer: NIOSH provides recommended
occupational exposure limits for carbon nanotubes, carbon nanofibres, silver nanoparticles, and
titanium dioxide
Why should biomedical laboratories develop and follow SOPs as a part of their hazard control
strategy? Answer: They help personnel prevent exposures
Nanotechnology has rapidly accelerated the development of new materials with diverse and
beneficial applications in the field of nanomedicine. Which of the following is a direct benefit of
nanomedicine? Answer: Improvements in cancer detection, drug delivery, and imaging
What is a potential route of exposure to nanomaterials in the workplace? Answer: Inhalation,
Skin Absorption, and Ingestion
Certain types of engineered nanoparticles may be hazardous, so proper engineering controls and
other precautions are required. For example, certain types of nanoparticles can penetrate the skin
while performing laboratory activities. Which of the following is a way to prevent skin
penetration? Answer: Tyvek type coveralls and impervious gloves
In which of the following scenarios should an institution appoint a biosafety officer (BSO)?
Answer: An NIH-funded institution engages research involving recombinant or synthetic
nucleic acid molecules and Risk Group 3 or 4 agents.
If an institution conducts research involving recombinant or synthetic nucleic acid molecules
involving exotic plants, or plants that may threaten an ecosystem, the IBC must have members
or ad hoc consultants with expertise in which of the following? Answer: Plant, plant pathogen,
or plant pest containment principles
Experiments involving recombinant or synthetic nucleic acid molecules that do not pose a
significant risk to health or the environment fall under which category of experiments in the
NIH Guidelines? Answer: Section III-F
APPHIA – Crafted with Care and Precision for Academic Excellence.
2
PERFECTION| STUDY WITH CONFIDENCE!
Course Code:
Course Title:
Programme:
Academic Year: 2026/2027.
Duration: 2 Hours.
Total Marks: 100.
Candidate Instructions:
1) Write your Registration Number on every answer booklet used.
2) Answer ALL questions in Section A and ANY TWO (2) questions in Section B.
3) Read each question carefully before answering.
4) Begin each question on a new page.
5) The marks for each question are indicated in brackets.
6) This paper consists of several printed pages, including this page.
7) Ensure your copy is complete before the examination begins.
8) Unauthorized materials and communication with other candidates are not permitted.
Turn Over.
APPHIA – Crafted with Care and Precision for Academic Excellence.
1
, If the PI does not agree with the IRE findings they can request: Answer: Review by the USG
Which of the following is a responsibility of the IRE? Answer: Notification within 30 days of
organizational review to the USG funding agency
For research to qualify as potential DURC, the PI and IRE must perform an initial assessment
on which of the following? Answer: Use of a listed agent or toxin that may result in one or
more of the seven experiments of concern
What organizations are required to have an IRE if DURC is being considered? Answer: Any
organization that receives money from the federal government
How often is IRE review required to determine if the research still falls under DURC or
enhanced measures are required? Answer: At least annually
Which of the following is accurate regarding the National Institute for Occupational Safety and
Health's (NIOSH) exposure limits for nanomaterials? Answer: NIOSH provides recommended
occupational exposure limits for carbon nanotubes, carbon nanofibres, silver nanoparticles, and
titanium dioxide
Why should biomedical laboratories develop and follow SOPs as a part of their hazard control
strategy? Answer: They help personnel prevent exposures
Nanotechnology has rapidly accelerated the development of new materials with diverse and
beneficial applications in the field of nanomedicine. Which of the following is a direct benefit of
nanomedicine? Answer: Improvements in cancer detection, drug delivery, and imaging
What is a potential route of exposure to nanomaterials in the workplace? Answer: Inhalation,
Skin Absorption, and Ingestion
Certain types of engineered nanoparticles may be hazardous, so proper engineering controls and
other precautions are required. For example, certain types of nanoparticles can penetrate the skin
while performing laboratory activities. Which of the following is a way to prevent skin
penetration? Answer: Tyvek type coveralls and impervious gloves
In which of the following scenarios should an institution appoint a biosafety officer (BSO)?
Answer: An NIH-funded institution engages research involving recombinant or synthetic
nucleic acid molecules and Risk Group 3 or 4 agents.
If an institution conducts research involving recombinant or synthetic nucleic acid molecules
involving exotic plants, or plants that may threaten an ecosystem, the IBC must have members
or ad hoc consultants with expertise in which of the following? Answer: Plant, plant pathogen,
or plant pest containment principles
Experiments involving recombinant or synthetic nucleic acid molecules that do not pose a
significant risk to health or the environment fall under which category of experiments in the
NIH Guidelines? Answer: Section III-F
APPHIA – Crafted with Care and Precision for Academic Excellence.
2
