USMLE WORLD QBANK NOTES WITH
100% CORRECT QUESTIONS AND
ANSWERS [GRADED A+]
If a guy comes in with cervical lymphadenopathy, what do you look for in
terms of planning treatment? - ✔✔Multiple, small rubbery nodes after a
URI? Just watch.
Associated symptoms like fevers, chills, weight loss? Did the nodes grow?
Are they greater than 2cm? Consider biopsy.
Young person comes in with fevers, joint pain, and rash. The rash starts on
the face and spreads down her body. Also posterior lymphadenopathy.
What is it? And why isn't it EBV? - ✔✔MEASLES.
©morren2025/2026.Year published 2026.
,EBV would involve CERVICAL LAD. Also accompanied by sore
throat/pharyngitis. Rash can occur but usually after administration of
ampicillin.
If you intubate someone and there are now decreased breath sounds on
the left, what happened? - ✔✔TUBE WENT DOWN RIGHT BRONCHUS.
No air going to left lung. Wouldn't want to increase tidal volume since that
would worsen oxygenation imbalance.
If an old guy comes in with elevated alk phos but nothing else, what's going
on? - ✔✔Paget's. Metastasis is possible but would see other symptoms
like bone pain, lytic lesions on imaging etc. PSA would be > 4 and you'd
see elevated calcium
Hemorrhagic stroke vs. Ischemic stroke vs. Subarachnoid hemorrhage.
First test? How would hemorrhage appear vs ischemia? - ✔✔Hemorrhagic
stroke - symptoms manifest a little more gradually. HTN is the most
important risk factor.
©morren2025/2026.Year published 2026.
,Ischemic stroke - usually more sudden with a history of TIAs, carotid bruits,
a-fib.
Subarachnoid hemorrhage - suden dramatic onset headache
First step is a non-contrast CT to distinguish between hemorrhagic or
ischemic stroke.
Hemorrhage = hyperdense (white)
Infarct = hypodense (black)
How do you treat restless leg syndrome? - ✔✔Dopamine AGONISTS.
What are the signs of acromegaly? - ✔✔HTN
Increase in finger size
Coarse features
Skin tags
©morren2025/2026.Year published 2026.
, Measure GH levels after glucose load. The PANCREATIC insulin that is
released will suppress GH release since that's converted to IGF-1 and you
don't want TOO much insulin.
HUS?
TTP?
ITP?
Vitamin k deficiency?
vWD?
Hemophilia A? B?
DIC? - ✔✔HUS - thrombocytopenia, hemolytic anemia, PT/PTT normal
TTP - thrombocytopenia, mental status changes, normal PT/PTT
ITP = normal PT/PTT
Vitamin K deficiency = prolonged PT, normal PTT
vWD = isolated PTT due to carrying of factor 8
©morren2025/2026.Year published 2026.
100% CORRECT QUESTIONS AND
ANSWERS [GRADED A+]
If a guy comes in with cervical lymphadenopathy, what do you look for in
terms of planning treatment? - ✔✔Multiple, small rubbery nodes after a
URI? Just watch.
Associated symptoms like fevers, chills, weight loss? Did the nodes grow?
Are they greater than 2cm? Consider biopsy.
Young person comes in with fevers, joint pain, and rash. The rash starts on
the face and spreads down her body. Also posterior lymphadenopathy.
What is it? And why isn't it EBV? - ✔✔MEASLES.
©morren2025/2026.Year published 2026.
,EBV would involve CERVICAL LAD. Also accompanied by sore
throat/pharyngitis. Rash can occur but usually after administration of
ampicillin.
If you intubate someone and there are now decreased breath sounds on
the left, what happened? - ✔✔TUBE WENT DOWN RIGHT BRONCHUS.
No air going to left lung. Wouldn't want to increase tidal volume since that
would worsen oxygenation imbalance.
If an old guy comes in with elevated alk phos but nothing else, what's going
on? - ✔✔Paget's. Metastasis is possible but would see other symptoms
like bone pain, lytic lesions on imaging etc. PSA would be > 4 and you'd
see elevated calcium
Hemorrhagic stroke vs. Ischemic stroke vs. Subarachnoid hemorrhage.
First test? How would hemorrhage appear vs ischemia? - ✔✔Hemorrhagic
stroke - symptoms manifest a little more gradually. HTN is the most
important risk factor.
©morren2025/2026.Year published 2026.
,Ischemic stroke - usually more sudden with a history of TIAs, carotid bruits,
a-fib.
Subarachnoid hemorrhage - suden dramatic onset headache
First step is a non-contrast CT to distinguish between hemorrhagic or
ischemic stroke.
Hemorrhage = hyperdense (white)
Infarct = hypodense (black)
How do you treat restless leg syndrome? - ✔✔Dopamine AGONISTS.
What are the signs of acromegaly? - ✔✔HTN
Increase in finger size
Coarse features
Skin tags
©morren2025/2026.Year published 2026.
, Measure GH levels after glucose load. The PANCREATIC insulin that is
released will suppress GH release since that's converted to IGF-1 and you
don't want TOO much insulin.
HUS?
TTP?
ITP?
Vitamin k deficiency?
vWD?
Hemophilia A? B?
DIC? - ✔✔HUS - thrombocytopenia, hemolytic anemia, PT/PTT normal
TTP - thrombocytopenia, mental status changes, normal PT/PTT
ITP = normal PT/PTT
Vitamin K deficiency = prolonged PT, normal PTT
vWD = isolated PTT due to carrying of factor 8
©morren2025/2026.Year published 2026.
