,NSG 124 Exam 3 Pharmacology Questions And Answers 2026/2027
HERZING UNIVERSITY
Q1. Which medication is an angiotensin-converting enzyme
inhibitor?
A) Lisinopril
B) Losartan
C) Metoprolol
D) Amlodipine
Correct Answer: A) Lisinopril
Rationale: Lisinopril is an ACE inhibitor that decreases formation of
angiotensin II and thereby promotes vasodilation and reduced blood
pressure.
Q2. Which therapeutic effect is expected from an ACE inhibitor?
A) Increased vasoconstriction
B) Decreased blood pressure
C) Increased sodium retention
D) Increased aldosterone activity
Correct Answer: B) Decreased blood pressure
Rationale: ACE inhibition reduces angiotensin II formation, decreasing
vasoconstriction and aldosterone-mediated sodium retention.
Q3. Which adverse effect is particularly characteristic of ACE
inhibitors?
A) Persistent dry cough
B) Severe constipation
C) Orange discoloration of urine
D) Tendon rupture
Correct Answer: A) Persistent dry cough
Rationale: ACE inhibitors increase bradykinin levels, which can produce a
persistent dry cough.
Q4. A client taking lisinopril develops swelling of the tongue and
difficulty breathing. What is the nurse's priority action?
A) Document the expected effect
B) Administer the next dose with food
C) Treat the finding as an emergency and address the airway
D) Encourage potassium intake
Correct Answer: C) Treat the finding as an emergency and address the airway
Rationale: Tongue and airway swelling may indicate angioedema, a
potentially life-threatening reaction requiring immediate intervention.
, Q5. Which laboratory finding is particularly important to monitor in
a client taking an ACE inhibitor?
A) Serum potassium
B) Hemoglobin A1c only
C) Platelet count only
D) Serum amylase only
Correct Answer: A) Serum potassium
Rationale: ACE inhibitors can reduce aldosterone activity and cause
potassium retention, creating a risk for hyperkalemia.
Q6. Which client statement indicates a need for additional teaching
about lisinopril?
A) "I will report swelling of my face or tongue."
B) "I will check my blood pressure as instructed."
C) "I can freely use potassium-containing salt substitutes."
D) "I will report a persistent cough."
Correct Answer: C) "I can freely use potassium-containing salt substitutes."
Rationale: Potassium-containing salt substitutes can increase the risk of
hyperkalemia during ACE inhibitor therapy.
Q7. Which medication is an angiotensin II receptor blocker?
A) Losartan
B) Enalapril
C) Captopril
D) Lisinopril
Correct Answer: A) Losartan
Rationale: Losartan is an ARB that blocks the effects of angiotensin II at its
receptor.
Q8. Which adverse effect may occur with both ACE inhibitors and
ARBs?
A) Fetal harm
B) Orange urine
C) Severe constipation in every client
D) Increased thyroid hormone production
Correct Answer: A) Fetal harm
Rationale: Drugs that interfere with the renin-angiotensin system can cause
serious fetal injury and are contraindicated during pregnancy.
Q9. Which statement best differentiates ARBs from ACE inhibitors?
A) ARBs directly block angiotensin II receptors
B) ARBs increase angiotensin II effects
HERZING UNIVERSITY
Q1. Which medication is an angiotensin-converting enzyme
inhibitor?
A) Lisinopril
B) Losartan
C) Metoprolol
D) Amlodipine
Correct Answer: A) Lisinopril
Rationale: Lisinopril is an ACE inhibitor that decreases formation of
angiotensin II and thereby promotes vasodilation and reduced blood
pressure.
Q2. Which therapeutic effect is expected from an ACE inhibitor?
A) Increased vasoconstriction
B) Decreased blood pressure
C) Increased sodium retention
D) Increased aldosterone activity
Correct Answer: B) Decreased blood pressure
Rationale: ACE inhibition reduces angiotensin II formation, decreasing
vasoconstriction and aldosterone-mediated sodium retention.
Q3. Which adverse effect is particularly characteristic of ACE
inhibitors?
A) Persistent dry cough
B) Severe constipation
C) Orange discoloration of urine
D) Tendon rupture
Correct Answer: A) Persistent dry cough
Rationale: ACE inhibitors increase bradykinin levels, which can produce a
persistent dry cough.
Q4. A client taking lisinopril develops swelling of the tongue and
difficulty breathing. What is the nurse's priority action?
A) Document the expected effect
B) Administer the next dose with food
C) Treat the finding as an emergency and address the airway
D) Encourage potassium intake
Correct Answer: C) Treat the finding as an emergency and address the airway
Rationale: Tongue and airway swelling may indicate angioedema, a
potentially life-threatening reaction requiring immediate intervention.
, Q5. Which laboratory finding is particularly important to monitor in
a client taking an ACE inhibitor?
A) Serum potassium
B) Hemoglobin A1c only
C) Platelet count only
D) Serum amylase only
Correct Answer: A) Serum potassium
Rationale: ACE inhibitors can reduce aldosterone activity and cause
potassium retention, creating a risk for hyperkalemia.
Q6. Which client statement indicates a need for additional teaching
about lisinopril?
A) "I will report swelling of my face or tongue."
B) "I will check my blood pressure as instructed."
C) "I can freely use potassium-containing salt substitutes."
D) "I will report a persistent cough."
Correct Answer: C) "I can freely use potassium-containing salt substitutes."
Rationale: Potassium-containing salt substitutes can increase the risk of
hyperkalemia during ACE inhibitor therapy.
Q7. Which medication is an angiotensin II receptor blocker?
A) Losartan
B) Enalapril
C) Captopril
D) Lisinopril
Correct Answer: A) Losartan
Rationale: Losartan is an ARB that blocks the effects of angiotensin II at its
receptor.
Q8. Which adverse effect may occur with both ACE inhibitors and
ARBs?
A) Fetal harm
B) Orange urine
C) Severe constipation in every client
D) Increased thyroid hormone production
Correct Answer: A) Fetal harm
Rationale: Drugs that interfere with the renin-angiotensin system can cause
serious fetal injury and are contraindicated during pregnancy.
Q9. Which statement best differentiates ARBs from ACE inhibitors?
A) ARBs directly block angiotensin II receptors
B) ARBs increase angiotensin II effects
