NUR 239 EXAM 2 PHARMACOLOGY ANALGESICS QUESTIONS
AND ANSWERS | NUR 239 STUDY GUIDE & PRACTICE TEST
2026/2027
chemical mediators found in most body tissues - ANS ✔✔What are prostaglandins?
regulates core body temp - ANS ✔✔The hypothalamus:
when cellular injury (inflammation) occurs - ANS ✔✔When are prostaglandins formed?
enzyme responsible for the formation of prostaglandins - ANS ✔✔What is cyclooxygenase?
COX-1 is normally, always produced; COX-2 is only active until pain or inflammation - ANS ✔✔What is the
difference between COX-1 and COX-2?
in CNS and peripheral tissues - ANS ✔✔Where does aspirin act?
stomach problems, renal issues, constriction of vessels, decrease platelet aggregation - ANS ✔✔What
are the common adverse effects of anti-prostaglandins?
acetylsalicylic acid - ANS ✔✔What is the chemical name for Aspirin?
anti-pyretic, non-opioid analgesic, salicylate - ANS ✔✔Classes/Categories for Aspirin:
inhibitting prostaglandin synthesis in CNS and peripheral tissues. Decreases platelet aggregation. - ANS
✔✔Expected pharmacological action of Aspirin?
analgesia, reduction of inflammation, reduction of fever, decreased heart attacks and ischemic attacks -
ANS ✔✔Therapeutic Use for Aspirin:
Risk of bleeding, renal toxicity, tinnitus, GI bleeding, hemorrhage/petechiae/burning - ANS
✔✔Complications of Aspirin:
intravenous sodium bicarbonate --> produces alkaline urine to help excrete med - ANS ✔✔How do you
treat Aspirin toxicity?
Known sensitivity, bleeding risk - ANS ✔✔What are the contraindications of Aspirin?
Yes. Reye Syndrome (brain and liver) in kids and teens - ANS ✔✔Is there a Black Box Warning for Aspirin?
salicylism - ANS ✔✔What is Aspirin toxicity called?
- Increased risk for bleeding when used with warfarin and heparin
- Ibuprofen may negate anti-platelet affects - ANS ✔✔What are known interactions with Aspirin?
, 325-650mg PO - ANS ✔✔What is the normal dose of Aspirin?
8000mg - ANS ✔✔What is the maximum daily dose for Aspirin?
- Monitor for bleeding, ringing in ears, loss of hearing
- Don't give 1-2 weeks before surgery - ANS ✔✔Nursing Interventions for Aspirin:
- Take with water
- Report tinnitus, bleeding of gums
- Avoid alcohol - ANS ✔✔Client Education for Aspirin:
No, cross placenta easily - ANS ✔✔Can you take Aspirin during pregnancy?
No - ANS ✔✔Can you chew or crush sustained release tablets?
No, risk for Reye Syndrome - ANS ✔✔"My baby has the flu, can I give him baby aspirin?"
No, will irritate the stomach lining and work too aggressively - ANS ✔✔"My husband needs to take
enteric coated aspirin. Sometimes he has trouble swallowing because of his Parkinson's Disease. Can I
crush the tablet or have him chew it?"
Ibuprofen - ANS ✔✔What is the prototype of proprionic acid derivatives?
similiar to ibuprofen; in same class - ANS ✔✔What is naproxen?
peripherally in the tissues - ANS ✔✔Where do Ibuprofen and Naproxen work in the body?
anti-pyretic, non-opioid analgesic, NSAID - ANS ✔✔What are the classes and categories for ibuprofen?
Blocks COX enzymes; prevents synthesis of prostaglandins - ANS ✔✔What is the pharmacologic action of
ibuprofen?
decrease pain, inflammation, fever - ANS ✔✔What is the therapeutic action of ibuprofen?
Nephrotoxicity (elevated BUN/creatine lab), GI ulcerations - ANS ✔✔What are the complications of
Ibuprofen?
renal impairment - ANS ✔✔Long-term use of Ibuprofen can lead to:
Hypersensitivity to NSAIDS and salicylates (Aspirin) - ANS ✔✔Contraindications of Ibuprofen:
400mg to 800mg PO - ANS ✔✔What is the average dose for ibuprofen?
liquid suspension, IV infusion - ANS ✔✔What other routes does ibuprofen come in?
3200mg - ANS ✔✔What's the maximum daily dosage for ibuprofen?
AND ANSWERS | NUR 239 STUDY GUIDE & PRACTICE TEST
2026/2027
chemical mediators found in most body tissues - ANS ✔✔What are prostaglandins?
regulates core body temp - ANS ✔✔The hypothalamus:
when cellular injury (inflammation) occurs - ANS ✔✔When are prostaglandins formed?
enzyme responsible for the formation of prostaglandins - ANS ✔✔What is cyclooxygenase?
COX-1 is normally, always produced; COX-2 is only active until pain or inflammation - ANS ✔✔What is the
difference between COX-1 and COX-2?
in CNS and peripheral tissues - ANS ✔✔Where does aspirin act?
stomach problems, renal issues, constriction of vessels, decrease platelet aggregation - ANS ✔✔What
are the common adverse effects of anti-prostaglandins?
acetylsalicylic acid - ANS ✔✔What is the chemical name for Aspirin?
anti-pyretic, non-opioid analgesic, salicylate - ANS ✔✔Classes/Categories for Aspirin:
inhibitting prostaglandin synthesis in CNS and peripheral tissues. Decreases platelet aggregation. - ANS
✔✔Expected pharmacological action of Aspirin?
analgesia, reduction of inflammation, reduction of fever, decreased heart attacks and ischemic attacks -
ANS ✔✔Therapeutic Use for Aspirin:
Risk of bleeding, renal toxicity, tinnitus, GI bleeding, hemorrhage/petechiae/burning - ANS
✔✔Complications of Aspirin:
intravenous sodium bicarbonate --> produces alkaline urine to help excrete med - ANS ✔✔How do you
treat Aspirin toxicity?
Known sensitivity, bleeding risk - ANS ✔✔What are the contraindications of Aspirin?
Yes. Reye Syndrome (brain and liver) in kids and teens - ANS ✔✔Is there a Black Box Warning for Aspirin?
salicylism - ANS ✔✔What is Aspirin toxicity called?
- Increased risk for bleeding when used with warfarin and heparin
- Ibuprofen may negate anti-platelet affects - ANS ✔✔What are known interactions with Aspirin?
, 325-650mg PO - ANS ✔✔What is the normal dose of Aspirin?
8000mg - ANS ✔✔What is the maximum daily dose for Aspirin?
- Monitor for bleeding, ringing in ears, loss of hearing
- Don't give 1-2 weeks before surgery - ANS ✔✔Nursing Interventions for Aspirin:
- Take with water
- Report tinnitus, bleeding of gums
- Avoid alcohol - ANS ✔✔Client Education for Aspirin:
No, cross placenta easily - ANS ✔✔Can you take Aspirin during pregnancy?
No - ANS ✔✔Can you chew or crush sustained release tablets?
No, risk for Reye Syndrome - ANS ✔✔"My baby has the flu, can I give him baby aspirin?"
No, will irritate the stomach lining and work too aggressively - ANS ✔✔"My husband needs to take
enteric coated aspirin. Sometimes he has trouble swallowing because of his Parkinson's Disease. Can I
crush the tablet or have him chew it?"
Ibuprofen - ANS ✔✔What is the prototype of proprionic acid derivatives?
similiar to ibuprofen; in same class - ANS ✔✔What is naproxen?
peripherally in the tissues - ANS ✔✔Where do Ibuprofen and Naproxen work in the body?
anti-pyretic, non-opioid analgesic, NSAID - ANS ✔✔What are the classes and categories for ibuprofen?
Blocks COX enzymes; prevents synthesis of prostaglandins - ANS ✔✔What is the pharmacologic action of
ibuprofen?
decrease pain, inflammation, fever - ANS ✔✔What is the therapeutic action of ibuprofen?
Nephrotoxicity (elevated BUN/creatine lab), GI ulcerations - ANS ✔✔What are the complications of
Ibuprofen?
renal impairment - ANS ✔✔Long-term use of Ibuprofen can lead to:
Hypersensitivity to NSAIDS and salicylates (Aspirin) - ANS ✔✔Contraindications of Ibuprofen:
400mg to 800mg PO - ANS ✔✔What is the average dose for ibuprofen?
liquid suspension, IV infusion - ANS ✔✔What other routes does ibuprofen come in?
3200mg - ANS ✔✔What's the maximum daily dosage for ibuprofen?
