MICROBIOLOGY EXAM TEST QUESTIONS AND
ANSWERS VERIFIED
1. A 22-year old woman with slight fever (38.5C), a complaint of frequent urination,
burning on urination, vaginal discharge and a small lesion on the labia. The woman had
three sexual partners in the past six months. Her last sexual contacts were about 7 days
earlier. Developed mild symptoms about 5 days earlier, beginning with a discharge from
the vagina. Pain on urination about 3 days earlier. Urine analysis revealed a pH of 8.2,
some white cells and a few red blood cells. A smear of the vaginal secretion showed a
number of
Gram-negative cocci.:
1) What is your diagnosis here?
Gonorrhea or vaginitis.
2) What clinical features are critical to your diagnosis?
Gram-negative cocci, time in which the symptoms appeared, high pH of urine, and
vaginal secretions or discharge
3) What medication would you precribe, if any? Tequin or sethtrokin
4) What further actions must be taken?
Practice safe sex
Prescribe Doxycylin if Chlamydia is also contracted
Sexual partners should be tested and treated
Do not participate in sexual activity until infection has subsided
2. A 62-year old diabetic black man presents in the emergency room with a swollen left
leg with areas of blanching and blue mottling. A "foul odor" is coming from a dressed
wound. The physicians remove the dressing and a brownish fluid is seeping from a
wounded area. The fluid contains what appear to be small bits of the tissue. No pus
appears to be present. The wound has a strong "rotten" odor. Five days earlier, while at
his work as a farmer, he caught the leg in his manure spreader, sustaining a deep,
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crushing, grossly dirty injury. His wife cleaned the wound as well as she could with soap
and water, dressed it with clean gauze, and wrapped it tightly with an elastic bandage to
stop the bleeding. The second day they redressed the wound and applied triple antibiotic
ointment. The patient treated his pain with ibuprofen (Advil). He reported the pain was
not very bad for the first 72 hours. In the past 24 hours, the leg swelled and the mottling
began to appear. A foul odor and severe pain accompanied the swelling.: 1) What is your
diagnosis in this case?
Gas gangrene (Clostridium)
2) How should this wound be treated?
Remove dead and infected tissue, amputation is necessary; antibiotics for treatment- IV
antibiotics
3) Is this a life-threatening condition?
Yes very. It moves fast, and only gets worse
4) What is the significance of his diabetes, if any?
Blood supply inadequate to wound/throughout the body; components needed to heal
cannot be properly be delivered due to the diabetes
3. A 58-year old lawyer presents in the emergency room with headache, irritability,
generalized muscle pain and uncontrollable back spasms. He has back spasms that
became extremely painful.
He is on medication for high blood pressure (beta blocker) and has mild asthma. He
injured himself about 10 days earlier, puncturing his left arm with a nail from an old barn
he is tearing. The wound has produced moderate quantities of pus, but he has been
keeping it clean. The wound was sampled for microscopic examination and culture, and
the results indicate gram-positive anaerobic, bacilli.
The back appears to have very tight contractions and spasms.: 1) What is your
diagnosis here? Teatnus
2) What is the scientific name of the organism? Clostridium tetani
3) What is the proper treatment of this problem?