(NGN) Q & A 100% VERIFIED ANSWERS
WITH RATIONALES 2026/2027
125 Questions with Answers and Detailed Rationales
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IMPORTANCE OF THIS DOCUMENT
This comprehensive examination preparation guide has been meticulously developed to help you succeed in the
ATI COMPREHENSIVE EXIT EXAM (NGN) Q & A 100% VERIFIED ANSWERS WITH RATIONALES 2026/2027.
It contains 125 carefully selected questions that reflect the most current exam content and testing strategies.
Each question is accompanied by a correct answer and a detailed rationale that explains the underlying
pathophysiology, pharmacology, or clinical reasoning.
Self-Assessment – Test your knowledge and Exam Preparation – Familiarize yourself with the
identify areas requiring further question format and content
study areas
Concept Reinforcement – Deepen your Confidence Building – Develop test-taking
understanding through strategies and reduce
evidence-based exam anxiety
rationales
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Review Summary 125 Questions
Foundations - Application - ATI Comprehensive EXIT NGN Q & A 100 WITH Rationales 2026/2027
Comprehensive Nursing NEXT Generation Nclex Undergraduate YEAR 4 / Pre-licensure
All answers with rationales
,Table of Contents
Content Area Questions Key Topics
Management OF CARE 1-21 Indicates, Finding, Intervention, Immediate, Prescribed
Safety AND Infection Control 22-42 Receiving, Finding, Nursing, Infusion, Requires
Health Promotion AND 43-63 Finding, Indicates, Prescribed, Receiving, Infusion
Maintenance
Psychosocial Integrity 64-84 Finding, Prescribed, Indicates, Immediate, Intervention
Basic CARE AND Comfort 85-105 Finding, Immediate, Indicates, Intervention, Receiving
Pharmacological Therapies 106-125 Finding, Laboratory, Nursing, Acute, Receiving
TOTAL 125 All questions include answers and detailed rationales
,Section A - Management OF CARE
Q1.
In a patient with an acute exacerbation of heart failure, which arterial blood gas (ABG)
value indicates the earliest compensatory response?
A. Decreased PaCO2 B. Increased serum bicarbonate
C. Decreased serum potassium D. Increased PaO2
Correct: A - Decreased PaCO2
Rationale:In acute respiratory acidosis (hypoventilation), the immediate compensatory
response is renal retention of bicarbonate, but this takes hours to days. The earliest
compensatory response is hyperventilation to decrease PaCO2, which occurs within minutes.
Increased bicarbonate is a later renal compensation. Decreased potassium and increased
PaO2 are not compensatory responses to acidosis.
Why the other answers are wrong:
B. Renal compensation occurs over hours to days, not acutely.
C. Potassium shifts are associated with acidosis but not an early compensatory mechanism.
D. Increased PaO2 is not a compensatory response to respiratory acidosis.
Reference: McCance, K.L., & Huether, S.E. (2026). Pathophysiology: The Biologic Basis for Disease in
Adults and Children, 9th Ed., Ch. 30.
Q2.
A nurse is evaluating a client's telemetry rhythm. Which finding indicates the need for
immediate intervention?
A. PR interval of 0.20 seconds B. QRS duration of 0.12 seconds
C. Ventricular rate of 120/min with absent P D. Sinus arrhythmia with rate change with
waves respiration
Correct: C - Ventricular rate of 120/min with absent P waves
Rationale:A ventricular rate of 120/min with absent P waves suggests supraventricular
tachycardia or atrial fibrillation with rapid ventricular response, which can compromise cardiac
output and requires intervention. A PR interval of 0.20 seconds is normal. A QRS duration of
0.12 seconds is borderline but not immediate. Sinus arrhythmia is a normal variant.
Why the other answers are wrong:
A. PR interval 0.20 seconds is at the upper limit of normal.
B. QRS 0.12 seconds is borderline but not immediately life-threatening.
D. Sinus arrhythmia is a benign finding, especially in young adults.
Reference: Hinkle, J.L., & Cheever, K.H. (2026). Brunner & Suddarth's Textbook of Medical-Surgical
Page 3
, Section A - Management OF CARE
Nursing, 16th Ed., Ch. 25.
Q3.
A client with type 2 diabetes is prescribed metformin. Which instruction is most important
to include?
A. Take the medication with meals to reduce B. Report any episodes of hypoglycemia
gastrointestinal upset. immediately.
C. Discontinue the medication if a contrast D. Expect a weight gain of 2 to 4 pounds
dye study is planned. during the first month.
Correct: C - Discontinue the medication if a contrast dye study is planned.
Rationale:Metformin is contraindicated in patients who will receive iodinated contrast media
due to the risk of lactic acidosis and acute kidney injury. The medication should be held at the
time of the procedure and resumed 48 hours after if renal function is normal. Taking with
meals reduces GI upset but is not the most important. Hypoglycemia is uncommon with
metformin monotherapy. Weight gain is not typical; metformin is weight-neutral.
Why the other answers are wrong:
A. While true, it is not the most critical instruction.
B. Metformin rarely causes hypoglycemia when used alone.
D. Metformin does not cause weight gain; it may cause mild weight loss.
Reference: Lehne, R.A. (2026). Pharmacology for Nursing Care, 12th Ed., Ch. 45.
Q4.
A postpartum client develops sudden onset of dyspnea, chest pain, and hypotension.
Which condition should the nurse suspect first?
A. Amniotic fluid embolism B. Pulmonary embolism
C. Postpartum hemorrhage D. Peripartum cardiomyopathy
Correct: A - Amniotic fluid embolism
Rationale:Amniotic fluid embolism (AFE) is a catastrophic obstetric emergency characterized
by sudden dyspnea, hypoxia, hypotension, and coagulopathy, often occurring during labor or
immediately postpartum. Pulmonary embolism can present similarly but is less sudden and
typically occurs later. Postpartum hemorrhage presents with bleeding and shock. Peripartum
cardiomyopathy develops more gradually.
Why the other answers are wrong:
B. PE is a possibility but not the most immediate and dramatic presentation.
C. Hemorrhage presents with bleeding and hypovolemia, not primarily respiratory distress.
D. Peripartum cardiomyopathy has a more insidious onset.
Reference: Ricci, S.S. (2026). Essentials of Maternity, Newborn, and Women's Health Nursing, 5th Ed.,
Page 4