WGU D027 OBJECTIVE ASSESSMENT REVIEW (LATEST 20236/ 2027
UPDATE) ADVANCED PATHOPHARMACOLOGICAL FOUNDATIONS
09/12/2026
WGU D027 Objective Assessment (Latest 2026/
2027 Update) Advanced Pathopharmacological
Foundations| Questions and Verified Answers|
100% Correct
What is the gold standard for the suspected diagnosis of Celiac Disease?
Endoscopy with small intestine biopsy
A 44-year-old woman has recently been diagnosed with advanced metastatic non-small-cell lung cancer.
Genetic testing is ordered to determine if the patient's tumor has any genomic alterations and to guide
treatment decisions. A few weeks later, the patient's test results come back positive for a genetic
mutation. The APN starts osimertinib (Tagrisso). Based on this information, what type of genetic
mutation does this patient have?
EGFR mutation
A 20-year-old male meets with an advanced professional nurse (APN) to discuss symptoms that have
been slowly progressing over the past several years. He is mainly concerned because he has been falling
frequently. Since childhood, his gait has consisted of walking on his toes. During middle school, he was
able to participate in sports but was unable to participate in high school sports due to difficulty with
running and jumping. Lately, he has noticed it takes longer and is more difficult to change positions from
sitting to standing than it used to in the past. He has also been waking up with muscle and joint stiffness.
The APRN notes that his family history is not significant for any chronic or genetic diseases. Which
condition is likely to be the cause of these symptoms?
Becker muscular dystrophy
--Becker muscular dystrophy (often called Becker MD or BMD) is a form of muscular dystrophy, a
9/12/2026
genetic disorder that gradually makes the body's muscles weaker and smaller. It causes less severe
problems than the most common type, Duchenne muscular dystrophy.
1
, WGU D027 OBJECTIVE ASSESSMENT REVIEW (LATEST 20236/ 2027
UPDATE) ADVANCED PATHOPHARMACOLOGICAL FOUNDATIONS
09/12/2026
Which statement should the provider give the patient regarding the pathophysiology of SLE and its
relation to thrombocytopenia?
SLE disrupts immune homeostasis and promotes development of self-reactive antibodies.
A female patient presents to an office to establish care. Her previous primary care provider told her to
follow up regarding an elevated ferritin level. She has no previous medical history and is currently
asymptomatic. She is concerned about the elevated ferritin and would like to know if she should be
worried. What should the provider do next for this patient?
Order a liver function test
A 75-year-old female presents to the emergency department with an irregular heart rate of 130.What
can be ascertained about this patient's findings given the limited information?
She is diagnosed with atrial fibrillation and needs her heart rate controlled with metoprolol
(Lopressor).
Which condition from this patient's medical history is contributing to the loss of contractility?
Acute myocardial infarction
Which condition is this patient suffering from?
Diabetic ketoacidosis
9/12/2026
A 45-year-old female fears that she is having a stroke and takes herself to an emergency room. After
several diagnostic and laboratory tests, the patient is diagnosed with Cushing disease. Which lab
abnormality would be present in this patient?
2
, WGU D027 OBJECTIVE ASSESSMENT REVIEW (LATEST 20236/ 2027
UPDATE) ADVANCED PATHOPHARMACOLOGICAL FOUNDATIONS
09/12/2026
Increased cortisol
SOB when lying down, and moving around --Based on the patient's presentation, which disease process
is the patient likely exhibiting?
Asthma
A two-year-old child presents with a clear runny nose and cough which has lasted 3 days. The child's
mother reports the cough sounds like a barking noise. The child is sleeping in the mother's arms and
appears to have stridor. The child's mother also reports an axillary temperature of 101°F last night.
Which management technique is appropriate for this child's symptoms?
Oral steroids and breathing treatments
Delerium, urinary incontinence, fever-- Which lab and diagnostic tests should be ordered as part of the
patient's assessment?
Complete blood count, complete metabolic profile, and urinalysis
An 18-year-old male is involved in a motorcycle crash while not wearing a helmet. He is brought into an
emergency room and is immediately taken for a CT scan. The provider tells the patient's parents he has
bleeding between the dura mater and the skull. What is this patient's condition called?
Epidural hematoma
-- What is the appropriate diagnosis for this patient?
Crohn's disease
9/12/2026
3
UPDATE) ADVANCED PATHOPHARMACOLOGICAL FOUNDATIONS
09/12/2026
WGU D027 Objective Assessment (Latest 2026/
2027 Update) Advanced Pathopharmacological
Foundations| Questions and Verified Answers|
100% Correct
What is the gold standard for the suspected diagnosis of Celiac Disease?
Endoscopy with small intestine biopsy
A 44-year-old woman has recently been diagnosed with advanced metastatic non-small-cell lung cancer.
Genetic testing is ordered to determine if the patient's tumor has any genomic alterations and to guide
treatment decisions. A few weeks later, the patient's test results come back positive for a genetic
mutation. The APN starts osimertinib (Tagrisso). Based on this information, what type of genetic
mutation does this patient have?
EGFR mutation
A 20-year-old male meets with an advanced professional nurse (APN) to discuss symptoms that have
been slowly progressing over the past several years. He is mainly concerned because he has been falling
frequently. Since childhood, his gait has consisted of walking on his toes. During middle school, he was
able to participate in sports but was unable to participate in high school sports due to difficulty with
running and jumping. Lately, he has noticed it takes longer and is more difficult to change positions from
sitting to standing than it used to in the past. He has also been waking up with muscle and joint stiffness.
The APRN notes that his family history is not significant for any chronic or genetic diseases. Which
condition is likely to be the cause of these symptoms?
Becker muscular dystrophy
--Becker muscular dystrophy (often called Becker MD or BMD) is a form of muscular dystrophy, a
9/12/2026
genetic disorder that gradually makes the body's muscles weaker and smaller. It causes less severe
problems than the most common type, Duchenne muscular dystrophy.
1
, WGU D027 OBJECTIVE ASSESSMENT REVIEW (LATEST 20236/ 2027
UPDATE) ADVANCED PATHOPHARMACOLOGICAL FOUNDATIONS
09/12/2026
Which statement should the provider give the patient regarding the pathophysiology of SLE and its
relation to thrombocytopenia?
SLE disrupts immune homeostasis and promotes development of self-reactive antibodies.
A female patient presents to an office to establish care. Her previous primary care provider told her to
follow up regarding an elevated ferritin level. She has no previous medical history and is currently
asymptomatic. She is concerned about the elevated ferritin and would like to know if she should be
worried. What should the provider do next for this patient?
Order a liver function test
A 75-year-old female presents to the emergency department with an irregular heart rate of 130.What
can be ascertained about this patient's findings given the limited information?
She is diagnosed with atrial fibrillation and needs her heart rate controlled with metoprolol
(Lopressor).
Which condition from this patient's medical history is contributing to the loss of contractility?
Acute myocardial infarction
Which condition is this patient suffering from?
Diabetic ketoacidosis
9/12/2026
A 45-year-old female fears that she is having a stroke and takes herself to an emergency room. After
several diagnostic and laboratory tests, the patient is diagnosed with Cushing disease. Which lab
abnormality would be present in this patient?
2
, WGU D027 OBJECTIVE ASSESSMENT REVIEW (LATEST 20236/ 2027
UPDATE) ADVANCED PATHOPHARMACOLOGICAL FOUNDATIONS
09/12/2026
Increased cortisol
SOB when lying down, and moving around --Based on the patient's presentation, which disease process
is the patient likely exhibiting?
Asthma
A two-year-old child presents with a clear runny nose and cough which has lasted 3 days. The child's
mother reports the cough sounds like a barking noise. The child is sleeping in the mother's arms and
appears to have stridor. The child's mother also reports an axillary temperature of 101°F last night.
Which management technique is appropriate for this child's symptoms?
Oral steroids and breathing treatments
Delerium, urinary incontinence, fever-- Which lab and diagnostic tests should be ordered as part of the
patient's assessment?
Complete blood count, complete metabolic profile, and urinalysis
An 18-year-old male is involved in a motorcycle crash while not wearing a helmet. He is brought into an
emergency room and is immediately taken for a CT scan. The provider tells the patient's parents he has
bleeding between the dura mater and the skull. What is this patient's condition called?
Epidural hematoma
-- What is the appropriate diagnosis for this patient?
Crohn's disease
9/12/2026
3
