Basic and Clinical Pharmacology 14th Edition Test Bank Katzung & Trevor Comprehensive Questions and Answers

TEST BANK For Basic and Clinical Pharmacology,
bn bn bn bn bn bn bn




15th Edition by Bertram G. Katzung, Verified
bn bn b n bn bn bn bn bn bn




Chapters 1 – 66 bn bn b n bn bn

,Table of bn




Contents
1. Introduction: The Nature of Drugs & Drug Development & Regulation
bn
bn bn bn bn bn bn bn bn bn


2. Drug Receptors & Pharmacodynamics
bn bn bn


3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug
bn bn bn bn bn bn bn bn bn bn


Action
bn


4. Drug Biotransformation
bn


5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology bn bn bn


7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs bn bn bn


8. Cholinoceptor-Blocking Drugs bn


9. Adrenoceptor Agonists & Sympathomimetic Drugs bn bn bn bn


10. Adrenoceptor Antagonist Drugs bn bn


11. Antihypertensive Agents bn


12. Vasodilators & the Treatment of Angina Pectorisbn bn bn bn bn bn


13. Drugs Used in Heart Failure
bn bn bn bn


14. Agents Used in Cardiac Arrhythmias
bn bn bn bn


15. Diuretic Agents bn


16. Histamine, Serotonin, & the Ergot Alkaloids
bn bn bn bn bn


17. Vasoactive Peptides bn


18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
bn bn bn bn bn bn bn


19. Nitric Oxide bn


20. Drugs Used in Asthma
bn bn bn


21. Introduction to the Pharmacology of CNS Drugs bn bn bn bn bn bn


22. Sedative-Hypnotic Drugs bn


23. The Alcohols
bn


24. Antiseizure Drugs bn


25. General Anesthetics bn


26. Local Anesthetics
bn


27. Skeletal Muscle Relaxants bn bn


28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
bn bn bn bn bn bn bn


29. Antipsychotic Agents & Lithium bn bn bn


30. Antidepressant Agents bn


31. Opioid Agonists & Antagonists
bn bn bn


32. Drugs of Abuse bn bn


33. Agents Used in Cytopenias; Hematopoietic Growth Factors
bn bn bn bn bn bn


34. Drugs Used in Disorders of Coagulation
bn bn bn bn bn


35. Agents Used in Dyslipidemia
bn bn bn


36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs,
bn bn bn bn bn


Nonopioid Analgesics, &
bn b n bn


Drugs Used in Gout
bn bn bn


37. Hypothalamic & Pituitary Hormones bn bn bn


38. Thyroid & Antithyroid Drugs
bn bn bn


39. Adrenocorticosteroids & Adrenocortical Antagonists bn bn bn


40. The Gonadal Hormones & Inhibitors
bn bn bn bn


41. Pancreatic Hormones & Antidiabetic Drugs
bn bn bn bn


42. Agents That Affect Bone Mineral Homeostasis
bn bn bn bn bn


43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
bn bn bn bn bn bn bn

,44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, &
bn bn bn bn bn


bnOxazolidinones
45. Aminoglycosides & Spectinomycin bn bn


46. Sulfonamides, Trimethoprim, & Quinolones bn bn bn


47. Antimycobacterial Drugs bn


48. Antifungal Agents bn


49. Antiviral Agents bn


50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
bn bn bn bn bn bn


51. Clinical Use of Antimicrobial Agents
bn bn bn bn


52. Antiprotozoal Drugs bn


53. Clinical Pharmacology of the Antihelminthic Drugs
bn bn bn bn bn


54. Cancer Chemotherapy
bn


55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
bn bn bn bn bn


57. Heavy Metal Intoxication & Chelators
bn bn bn bn


58. Management of the Poisoned Patient bn bn bn bn


59. Special Aspects of Perinatal & Pediatric Pharmacology
bn bn bn bn bn bn


60. Special Aspects of Geriatric Pharmacology
bn bn bn bn


61. Dermatologic Pharmacology bn


62. Drugs Used in the Treatment of Gastrointestinal Diseases
bn bn bn bn bn bn bn


63. Therapeutic & Toxic Potential of Over-the-Counter Agents
bn bn bn bn bn bn


64. Dietary Supplements & Herbal Medications
bn bn bn bn


65. Rational Prescribing & Prescription Writing
bn bn bn bn


66. Important Drug Interactions & Their Mechanisms
bn bn bn bn bn




Chapter 1. Introduction: The Nature of Drugs & Drug Development &
bn bn bn bn bn bn bn bn bn bn


Regulation
bn




1. A nurse working in radiology administers iodine to a patient who is
bn bn bn bn bn bn bn bn bn bn bn


having a computed tomography (CT) scan. The nurse working on
b n bn bn bn bn bn bn bn bn bn


the oncology unit administers chemotherapy to patients who have
bn b n bn bn bn bn bn bn bn


cancer. At the Public Health Department, a nurse administers a
bn bn b n bn bn bn bn bn bn bn


measles-mumps- rubella (MMR) vaccine toa 14-month-old child as
bn b n bn bn bn bn bn bn


a routine immunization. Which branch of pharmacology best
bn bn b n bn bn bn bn bn


describes the actions of all three nurses?
bn bn bn b n bn bn bn




A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

Ans: B

, Feedback:

Pharmacology is the study of the biologic effects of chemicals.
bn bn bn bn bn bn bn bn bn


Nurses are involved with clinical pharmacology or
bn b n bn bn bn bn bn



pharmacotherapeutics, which is a branch of pharmacology that
bn b n bn bn bn bn bn bn



deals with the uses of drugs to treat, prevent, and diagnose
bn bn bn bn bn bn bn b n bn bn bn


disease. The radiology nurse is administering a drug to help
bn bn bn bn bn b n bn bn bn bn



diagnose a disease. The oncology nurse is administering a drug
bn bn bn bn bn bn bn b n bn bn



to help treat adisease. Pharmacoeconomics includes any costs
bn bn bn bn bn b n bn bn


involved in drug therapy.
bn bn bn bn


Pharmacodynamics involves how a drug affects the bn bn bn bn bn bn



body andpharmacokinetics is how the body acts on
bn b n bn bn bn bn bn bn



the body.
bn bn




2. When involved in phase III drug evaluation studies,
bn bn bn bn bn bn bn


what responsibilitieswould the nurse have?
bn b n bn bn bn




A) Working with animals who are given experimental drugs
bn bn bn bn bn bn bn




B) Choosing appropriate patients to be involved in the drug study
bn bn bn bn bn bn bn bn b n




C) Monitoring and observing patients closely for adverse effects
bn bn bn bn bn bn bn




D) Conducting research to determine effectiveness of the drug
bn bn bn bn bn bn bn




Ans: C

Feedback:

Phase III studies involve use of a drug in a vast clinical
bn bn bn bn bn bn bn bn bn bn bn


population in whichpatients are asked to record any symptoms
bn bn b n bn bn bn bn bn bn



they experience while taking thedrugs. Nurses may be
bn bn b n bn bn bn bn bn


responsible for helping collect and analyze the information to be
bn bn bn bn b n bn bn bn bn bn



shared with the Food and Drug Administration (FDA) butwould
bn bn bn bn bn bn b n bn bn


not conduct research independently because nurses do not
bn bn bn bn b n bn bn bn



prescribe medications. Use of animals in drug testing is done in
bn bn bn bn bn bn bn b n bn bn bn



the preclinical trials. Select patients who are involved in phase
bn bn bn bn bn bn bn bn b n bn


II studies to participate in studies where the participants have
bn bn bn bn bn bn bn bn bn bn


the disease the drug is intended to treat. These patients are
b n bn bn bn bn bn bn bn bn bn bn



monitored closely for drug action and adverse effects. Phase I
bn b n bn bn bn bn bn bn bn bn



studies involve healthy human volunteers who are usually paid
bn bn b n bn bn bn bn bn bn


for their participation. Nurses may observe for adverse effects
bn bn bn b n bn bn bn bn bn



and toxicity.
bn bn