NURS 660 EXAM 2 Questions with Verified
Correct Answers
Which medication has the SE of losing hair
Lithium
The pt is bipolar, and had a partial response to depakote and now is going to be
augmented with an atypical antipsychotic, the effects of atypical antipsychotics in non-
psychotic mania may be due to what
indirect effect on glutamate release via 5H2A antagonism
A pt has had some success with his current antidepression medication, has tried many
different antidepressants, so you decide to augment with L-methyl-folate. What is the
hypothesis behind L methyl Folate boosting the therapeutic efficacy of
antidepressants...what is the MOA?
boosts monamine neurotransmitter function in bipolar disorder
You have a pt that has been very depressed and has insomnia problems with
concentrations, weight loss and SI. You start them on an AD and his symptoms have
abated, however which of the following symptoms is the most likely to be residual
following the successful tx of other symptoms?
insomnia
Which class of antidepressant have a lower incidence of sexual SE? What medication is
used in the tx of BP/mania and is used in prophylaxis as well as antidepressant
augmentation? Which medication is this?
Wellbutrin
, What medication is a very potent CYP450 inhibitor and can dangerously elevate
lamotrigine?
Valproate
Which class of antidepressant has the worst discontinuation syndrome?
Cymbalta
You have a female pt complaining of lactating and is not pregnant w/ no children. She
has been taking risperidone. Which medication would you avoid if you were to switch
her to another med?"
Paliperidone
A pt is on Prozac and it has stopped working. Patient has been on many other
antidepressants and wants to try an MAOI now. How long do you need to stop Prozac
before starting MAOI?
5-6 weeks
What neurotransmitter are affected by TCAs?
Serotonin, dopamine, norepinorphrenie, 5HT
What TCA medication should absolutely not be used in combination with any other
MAOI?
chlomipramine
Please know what is the most potent property of trazodone by what neurotransmitter?
SEDATION; 5H2A
Correct Answers
Which medication has the SE of losing hair
Lithium
The pt is bipolar, and had a partial response to depakote and now is going to be
augmented with an atypical antipsychotic, the effects of atypical antipsychotics in non-
psychotic mania may be due to what
indirect effect on glutamate release via 5H2A antagonism
A pt has had some success with his current antidepression medication, has tried many
different antidepressants, so you decide to augment with L-methyl-folate. What is the
hypothesis behind L methyl Folate boosting the therapeutic efficacy of
antidepressants...what is the MOA?
boosts monamine neurotransmitter function in bipolar disorder
You have a pt that has been very depressed and has insomnia problems with
concentrations, weight loss and SI. You start them on an AD and his symptoms have
abated, however which of the following symptoms is the most likely to be residual
following the successful tx of other symptoms?
insomnia
Which class of antidepressant have a lower incidence of sexual SE? What medication is
used in the tx of BP/mania and is used in prophylaxis as well as antidepressant
augmentation? Which medication is this?
Wellbutrin
, What medication is a very potent CYP450 inhibitor and can dangerously elevate
lamotrigine?
Valproate
Which class of antidepressant has the worst discontinuation syndrome?
Cymbalta
You have a female pt complaining of lactating and is not pregnant w/ no children. She
has been taking risperidone. Which medication would you avoid if you were to switch
her to another med?"
Paliperidone
A pt is on Prozac and it has stopped working. Patient has been on many other
antidepressants and wants to try an MAOI now. How long do you need to stop Prozac
before starting MAOI?
5-6 weeks
What neurotransmitter are affected by TCAs?
Serotonin, dopamine, norepinorphrenie, 5HT
What TCA medication should absolutely not be used in combination with any other
MAOI?
chlomipramine
Please know what is the most potent property of trazodone by what neurotransmitter?
SEDATION; 5H2A
