SBB Human Blood Groups Final Exam
How would Ulex europaeus react with O, A, A2, B, A2B, O>A2>B>A2B>A1>A1B
A1B RBCs?
How could you distinguish serologically A1, A2 and A3 Dolichos biflorus can will react with A1 and not A2. A3 yields mixed field reactions
with anti-A and anti-A,B
What is the correct order of type of RBCs to transfuse in A, B, O; the residual anti-B in A RBCs is less immunogenic than the residual anti-
an AB patient when AB RBCs are not available? Why? A in B RBCs
What type of RBCs would you transfuse to a patient with RBCs transfused must lack the D and C antigens
anti-G
Can you detect a weak D using Gel Technology? No, because there is no washing phase
Can an Rh positive father and Rh positive mother yield Yes, if both parents are heterozygous for the D gene. Inheritance is autosomal
an Rh negative child recessive
What type of RBCs in regards to Rh phenotype would RBCs should be negative for the c and e antigens
you transfuse in a patient with anti-f
How could you solve an ABO discrepancy where Anti-M Treat A1 cells with ficin to denature the M antigen, repeat reverse grouping with
was causing aberrant results in reverse grouping when ficin-treated A1 cells.
the forward type is consistent with A blood group and
reverse as O?
Why do you see an anti-N like specificity in dialysis Formaldehyde induced antibody to 'N' due to formaldehyde used in dialysis
patients? procedures.
A patient types as follows: anti-A=4+, Anti-B=1+, A1 Anti-B was adsorbed out with RESt.
Cells=2+, B cells=4+. The ABO discrepancy led to
suspicion of a possible cold autoantibody based on
patient histopry and diagnosis. RESt was used in an
attept to adsorb the autoantobidy. The type was repeated
with adsorbed plasma Anit-A=4+, Anti-B=0, A1 cells=0, B
cells=0. What could be the cause of this discrepancy?
What enzyme may be useful in distinguishing anti-Ge2? papain
The beta 1-3 linkage between galactose and N- secretions
acetylglucosamine is found in?
Represents Type II chain Beta 1-4 linkage between galactose and N acetyl glucosamine
Represents decreasing concentrations of H antigen on O>A2>B>A2B>A1>A1B
RBCs
The ABO genes are located on what chromosome Chromosome 9
, SBB Human Blood Groups Final Exam
Which glycosyltransferase is needed before A and B L-fucosyltransferase
antigens are formed?
Which reflects the A3 subgroup mixed field reactions with Anti-A and Anti-A,B.
Which fo the following reflects the A el subgroup? Positive reactions with Anti-H
What clinical condition may yield positive reactions with hypogammaglobulinemia
Anti-A, negative with Anti-B, negative with A1 and B
cells.
What differentiates a Bombay anti-H from an anti-H cold reactivity at body temperature.
agglutinin?
This antigen is associated with linear carbohydrate i antigen
chains
The following reactions are found on a 35-year old male. Anti-M in plasma
Anti-A=4+, Anti-B=0, Anti-A,B=4+, A1 cells=3+, B
cells=4+, O cells=3+. How could these results be
explained?
Anti-IH would react best with which red blood cells? O RBCs
The acquired B phenomenon is only found in what ABO A blood group
group?
A2 subgroup Anti-A1 does not react. 1-8% of persons will produce Anti-A1
Anti-Lu3 is associated with Recessive type Lu(a-b-)
The dominant Lu(a-b-) type is associated with what In(Lu)
gene?
What substance could be used to rule out anti-E in the DTT
presence of anti-Lub?
Which pair of Lu alleles go together Lu8 and Lu14
Lu6 and Lu9
Au^a and Au^b
Persons who are group B are more common among Black/Asian
which population?
Red cells that lack glycophorin A, also lack En^a antigens
How would Ulex europaeus react with O, A, A2, B, A2B, O>A2>B>A2B>A1>A1B
A1B RBCs?
How could you distinguish serologically A1, A2 and A3 Dolichos biflorus can will react with A1 and not A2. A3 yields mixed field reactions
with anti-A and anti-A,B
What is the correct order of type of RBCs to transfuse in A, B, O; the residual anti-B in A RBCs is less immunogenic than the residual anti-
an AB patient when AB RBCs are not available? Why? A in B RBCs
What type of RBCs would you transfuse to a patient with RBCs transfused must lack the D and C antigens
anti-G
Can you detect a weak D using Gel Technology? No, because there is no washing phase
Can an Rh positive father and Rh positive mother yield Yes, if both parents are heterozygous for the D gene. Inheritance is autosomal
an Rh negative child recessive
What type of RBCs in regards to Rh phenotype would RBCs should be negative for the c and e antigens
you transfuse in a patient with anti-f
How could you solve an ABO discrepancy where Anti-M Treat A1 cells with ficin to denature the M antigen, repeat reverse grouping with
was causing aberrant results in reverse grouping when ficin-treated A1 cells.
the forward type is consistent with A blood group and
reverse as O?
Why do you see an anti-N like specificity in dialysis Formaldehyde induced antibody to 'N' due to formaldehyde used in dialysis
patients? procedures.
A patient types as follows: anti-A=4+, Anti-B=1+, A1 Anti-B was adsorbed out with RESt.
Cells=2+, B cells=4+. The ABO discrepancy led to
suspicion of a possible cold autoantibody based on
patient histopry and diagnosis. RESt was used in an
attept to adsorb the autoantobidy. The type was repeated
with adsorbed plasma Anit-A=4+, Anti-B=0, A1 cells=0, B
cells=0. What could be the cause of this discrepancy?
What enzyme may be useful in distinguishing anti-Ge2? papain
The beta 1-3 linkage between galactose and N- secretions
acetylglucosamine is found in?
Represents Type II chain Beta 1-4 linkage between galactose and N acetyl glucosamine
Represents decreasing concentrations of H antigen on O>A2>B>A2B>A1>A1B
RBCs
The ABO genes are located on what chromosome Chromosome 9
, SBB Human Blood Groups Final Exam
Which glycosyltransferase is needed before A and B L-fucosyltransferase
antigens are formed?
Which reflects the A3 subgroup mixed field reactions with Anti-A and Anti-A,B.
Which fo the following reflects the A el subgroup? Positive reactions with Anti-H
What clinical condition may yield positive reactions with hypogammaglobulinemia
Anti-A, negative with Anti-B, negative with A1 and B
cells.
What differentiates a Bombay anti-H from an anti-H cold reactivity at body temperature.
agglutinin?
This antigen is associated with linear carbohydrate i antigen
chains
The following reactions are found on a 35-year old male. Anti-M in plasma
Anti-A=4+, Anti-B=0, Anti-A,B=4+, A1 cells=3+, B
cells=4+, O cells=3+. How could these results be
explained?
Anti-IH would react best with which red blood cells? O RBCs
The acquired B phenomenon is only found in what ABO A blood group
group?
A2 subgroup Anti-A1 does not react. 1-8% of persons will produce Anti-A1
Anti-Lu3 is associated with Recessive type Lu(a-b-)
The dominant Lu(a-b-) type is associated with what In(Lu)
gene?
What substance could be used to rule out anti-E in the DTT
presence of anti-Lub?
Which pair of Lu alleles go together Lu8 and Lu14
Lu6 and Lu9
Au^a and Au^b
Persons who are group B are more common among Black/Asian
which population?
Red cells that lack glycophorin A, also lack En^a antigens
