PRACTICE QUESTIONS AND STUDY GUIDE COMPLETE ACCURATE
EXAM APPROVED QUESTIONS WITH WELL ELABORATED
ANSWERS AND DETAILED RATIONALES (100% CORRECT VERIFIED
ANSWERS) CURRENTLY UPDATED VERSION 2026 EDITION
|GUARANTEED PASS A+ |FULL REVISED ABFM + KSA DIABETES
CERTIFICATION EXAM |JUST RELEASED
1. A 45-year-old asymptomatic man with a BMI of 32 kg/m² has a
fasting plasma glucose of 118 mg/dL. Which one of the following is
the most appropriate next step to confirm a diagnosis of diabetes
mellitus?
A. Repeat fasting plasma glucose in 6 months
B. Obtain a hemoglobin A1c
C. Perform a 75-g oral glucose tolerance test
D. Reassure the patient that no further testing is needed
E. Start metformin empirically
Correct Answer: B
Rationale: A fasting plasma glucose of 100–125 mg/dL indicates
impaired fasting glucose (prediabetes). To confirm diabetes, either
a repeat fasting plasma glucose ≥126 mg/dL, an A1c ≥6.5%, or a
,2-hour plasma glucose ≥200 mg/dL during a 75-g OGTT is
required. Obtaining an A1c is the most practical single test to
clarify glycemic status in an asymptomatic patient. A single
elevated fasting glucose is not diagnostic without confirmation.
Reassurance alone is inappropriate given the prediabetic range.
Metformin is not indicated without a confirmed diagnosis of
diabetes.
2. Which one of the following A1c thresholds is diagnostic of
diabetes mellitus according to the American Diabetes Association?
A. ≥5.7%
B. ≥6.0%
C. ≥6.5%
D. ≥7.0%
E. ≥7.5%
Correct Answer: C
Rationale: The ADA diagnostic threshold for A1c is ≥6.5% (≥48
mmol/mol). A1c values of 5.7%–6.4% indicate prediabetes. A1c
≥7.0% is a common treatment target for many adults with diabetes
but is not the diagnostic threshold. A1c ≥7.5% is not a diagnostic
cutoff.
,3. A 52-year-old woman with no symptoms has a random plasma
glucose of 215 mg/dL. Which one of the following is required to
diagnose diabetes mellitus in this patient?
A. A repeat random glucose ≥200 mg/dL
B. Classic symptoms of hyperglycemia or hyperglycemic crisis
C. A fasting plasma glucose ≥100 mg/dL
D. An A1c ≥6.0%
E. A 2-hour OGTT glucose ≥140 mg/dL
Correct Answer: B
Rationale: A random plasma glucose ≥200 mg/dL in the presence
of classic symptoms of hyperglycemia (polyuria, polydipsia,
unexplained weight loss) or hyperglycemic crisis is diagnostic of
diabetes without requiring a second confirmatory test. In the
absence of symptoms, a second abnormal test is required. A fasting
glucose ≥100 mg/dL indicates prediabetes, not diabetes. An A1c
≥6.0% is also in the prediabetic range. A 2-hour OGTT glucose
≥140 mg/dL indicates impaired glucose tolerance.
, 4. Which one of the following autoantibodies is most commonly
associated with type 1 diabetes mellitus and should be monitored in
patients with a confirmed single IA-2 autoantibody?
A. Anti-GAD65
B. Anti-insulin
C. Anti-IA-2
D. Anti-ZnT8
E. Anti-islet cell cytoplasmic
Correct Answer: A
Rationale: The 2026 ADA Standards of Care added a
recommendation that patients with a confirmed single IA-2
autoantibody should be monitored similarly to people with stage 2
type 1 diabetes. Anti-GAD65 is the most commonly tested and
sensitive autoantibody for type 1 diabetes and should be included
in the monitoring panel. Anti-insulin and anti-ZnT8 are also
associated with type 1 diabetes but are less commonly used for
monitoring. Anti-islet cell cytoplasmic antibodies are less specific.
5. A 58-year-old man with a 10-year history of type 2 diabetes has an
A1c of 7.8% on metformin monotherapy. He has no cardiovascular
disease, heart failure, or chronic kidney disease. Which one of the