PHARM BLOCK 1 PARASYMPATHETIC NERVOUS SYSTEM
MEDICATIONS UPDATED VERSION WITH 100% COMPLETE
SOLUTION!!
1. Which branch of the autonomic nervous system maintains homeostasis;
promotes rest and digest?: Parasympathetic Nervous System (PNS)
2. Which branch of the autonomic nervous system prepares body for stress;
triggers fight or flight?: Sympathetic Nervous System (SNS)
3. The SNS has what type of preganglionic neurons?: Adrenergic
4. The PNS has what type of preganglionic neurons?: Cholinergic
5. What are chemical messengers released across synapses?: Neurotransmitters
6. What is the primary neurotransmitter in the PNS? It stimulates receptors.: -
Acetylcholine (ACh)
7. What enzyme breaks down acetylcholine, inhibiting its action?:
Acetylcholinesterase (AChE)
8. Acetylcholine (neurotransmitter) acts on what 2 receptors while moving
from the spinal cord to the effector organ?: Nicotinic receptor; Muscarinic receptor
9. What are the 5 types of muscarinic receptors?: M1; M2; M3; M4; M5
10. What indirect agonist prevents the breakdown of acetylcholine (by
acetylcholinesterase)?: Acetylcholinesterase Inhibitors (AChEI)
11. What inhibitor works to prolong the action of acetylcholine at the muscarinic
receptor site (effector organ)?: Acetylcholinesterase inhibitors (AChEI
12. Cholinergic agents modulate acetylcholine (ACh) effects. Indirect agonists
do what?: Prolong actions
13. Cholinergic agents modulate acetylcholine (ACh) effects. Agonists do
, what?: Mimic
14. Cholinergic agents modulate acetylcholine (ACh) effects. Antagonists do
what?: Antagonize (block/reverse)
15. Drugs that mimic or prolong actions of acetylcholine (ACh) are called what
(2 names)?: Parasympathomimetic/Cholinomimetic
16. Drugs that block acetylcholine effects are called what?: Anticholinergics
17. What are reversible blockers of acetylcholine receptors?: Competitive
Antagonists
18. What are irreversible blockers of acetylcholine receptors?: Noncompetitive
Antagonists
19. What are the 9 side effects of cholinergic agonists?: DUMBBELLS
Diarrhea
Urination
Miosis (pupil constriction)
Bradycardia
Bronchospasm
Emesis (vomiting)
Lacrimation
Lethargy
Salivation
20. What are the 6 general side effects of cholinergic crisis?: SLUDGE
Salivation; Lacrimation; Urination; Diarrhea; GI distress; Emesis
21. What are the 6 major uses for cholinomimetics (prolong ACh)?: Overdose;
MEDICATIONS UPDATED VERSION WITH 100% COMPLETE
SOLUTION!!
1. Which branch of the autonomic nervous system maintains homeostasis;
promotes rest and digest?: Parasympathetic Nervous System (PNS)
2. Which branch of the autonomic nervous system prepares body for stress;
triggers fight or flight?: Sympathetic Nervous System (SNS)
3. The SNS has what type of preganglionic neurons?: Adrenergic
4. The PNS has what type of preganglionic neurons?: Cholinergic
5. What are chemical messengers released across synapses?: Neurotransmitters
6. What is the primary neurotransmitter in the PNS? It stimulates receptors.: -
Acetylcholine (ACh)
7. What enzyme breaks down acetylcholine, inhibiting its action?:
Acetylcholinesterase (AChE)
8. Acetylcholine (neurotransmitter) acts on what 2 receptors while moving
from the spinal cord to the effector organ?: Nicotinic receptor; Muscarinic receptor
9. What are the 5 types of muscarinic receptors?: M1; M2; M3; M4; M5
10. What indirect agonist prevents the breakdown of acetylcholine (by
acetylcholinesterase)?: Acetylcholinesterase Inhibitors (AChEI)
11. What inhibitor works to prolong the action of acetylcholine at the muscarinic
receptor site (effector organ)?: Acetylcholinesterase inhibitors (AChEI
12. Cholinergic agents modulate acetylcholine (ACh) effects. Indirect agonists
do what?: Prolong actions
13. Cholinergic agents modulate acetylcholine (ACh) effects. Agonists do
, what?: Mimic
14. Cholinergic agents modulate acetylcholine (ACh) effects. Antagonists do
what?: Antagonize (block/reverse)
15. Drugs that mimic or prolong actions of acetylcholine (ACh) are called what
(2 names)?: Parasympathomimetic/Cholinomimetic
16. Drugs that block acetylcholine effects are called what?: Anticholinergics
17. What are reversible blockers of acetylcholine receptors?: Competitive
Antagonists
18. What are irreversible blockers of acetylcholine receptors?: Noncompetitive
Antagonists
19. What are the 9 side effects of cholinergic agonists?: DUMBBELLS
Diarrhea
Urination
Miosis (pupil constriction)
Bradycardia
Bronchospasm
Emesis (vomiting)
Lacrimation
Lethargy
Salivation
20. What are the 6 general side effects of cholinergic crisis?: SLUDGE
Salivation; Lacrimation; Urination; Diarrhea; GI distress; Emesis
21. What are the 6 major uses for cholinomimetics (prolong ACh)?: Overdose;
