CDCES Exam - Medications
Metformin (Glucophage) drug class
biguanides
metformin (Glucophage) dose
500 to 2500 mg/day
metformin (Glucophage) aspect outcomes
- nausea
- bloating
- diarrhea
- B12 deficiency
Riomet
liquid metformin
biguanide benefits
- lowers ldl cholesterol
- no hypoglycemia
- weight impartial
- low-cost
biguanide use in pediatrics
accepted for children 10+ years
3 sorts of prolonged release/XR metformin
- Glucophage XR
- Glumetza
- Fortamet
biguanide effect on A1c
lowers A1c through 1 - 2%
,biguanide renal/GFR considerations
GFR <30... Do now not use
GFR <45... Do not begin metformin
If on metformin and GFR decreases to <30, eval risk/benefit or lower dose
three styles of sulfonylureas
- glipizide (Diabeta)
- glipizide (Glucotrol, "" XL)
- glimepiride (Amaryl)
doses for sulfonylureas
glyburide (Diabeta)... 1.25 to 20 QD
glipizide (Glucotrol)... 2.5 to 40 mg QD
glipizide (Glucotrol XL)... 2.Five to 20 mg QD
glimepiride (Amaryl)... 1.Zero to eight mg QD
How/wherein are sulfonylureas removed??
Kidneys
sulfonylurea effect on A1c
Lowers A1c through 1 - 2%
Sulfonylurea maximum in all likelihood to cause hypoglycemia
glyburide
4 kinds of SGLT2 inhibitors (established/logo names)
- canagliflozin (Invokana)
- dapagliflozin (Farxiga)
- empagliflozin (Jardiance)
- ertugliflozin (Steglatro)
, canagliflozin (Invokana) dosing
100 to 300 mg QD
If GFR 30-60, max dose a hundred mg
Image: canagliflozin (Invokana) dosing
dapagliflozin (Farxiga) dosing
five to 10 mg QD
If GFR <45, see packaging
Image: dapagliflozin (Farxiga) dosing
empagliflozin (Jardiance) dosing
10 to twenty-five mg QD
If GFR <forty five, see packaging
Image: empagliflozin (Jardiance) dosing
ertugliflozin (Steglatro) dosing
5 to 15 mg QD
If GFR <60, see package insert
Image: ertugliflozin (Steglatro) dosing
five aspect outcomes of SGLT2 inhibitors
- hypotension
- UTIs
- increased urination
- genital contamination
- ketoacidosis
Cardio and renal blessings of...
- canagliflozin (Invokana)
- dapagliflozin (Farxiga)
- empagliflozin (Jardiance)
Metformin (Glucophage) drug class
biguanides
metformin (Glucophage) dose
500 to 2500 mg/day
metformin (Glucophage) aspect outcomes
- nausea
- bloating
- diarrhea
- B12 deficiency
Riomet
liquid metformin
biguanide benefits
- lowers ldl cholesterol
- no hypoglycemia
- weight impartial
- low-cost
biguanide use in pediatrics
accepted for children 10+ years
3 sorts of prolonged release/XR metformin
- Glucophage XR
- Glumetza
- Fortamet
biguanide effect on A1c
lowers A1c through 1 - 2%
,biguanide renal/GFR considerations
GFR <30... Do now not use
GFR <45... Do not begin metformin
If on metformin and GFR decreases to <30, eval risk/benefit or lower dose
three styles of sulfonylureas
- glipizide (Diabeta)
- glipizide (Glucotrol, "" XL)
- glimepiride (Amaryl)
doses for sulfonylureas
glyburide (Diabeta)... 1.25 to 20 QD
glipizide (Glucotrol)... 2.5 to 40 mg QD
glipizide (Glucotrol XL)... 2.Five to 20 mg QD
glimepiride (Amaryl)... 1.Zero to eight mg QD
How/wherein are sulfonylureas removed??
Kidneys
sulfonylurea effect on A1c
Lowers A1c through 1 - 2%
Sulfonylurea maximum in all likelihood to cause hypoglycemia
glyburide
4 kinds of SGLT2 inhibitors (established/logo names)
- canagliflozin (Invokana)
- dapagliflozin (Farxiga)
- empagliflozin (Jardiance)
- ertugliflozin (Steglatro)
, canagliflozin (Invokana) dosing
100 to 300 mg QD
If GFR 30-60, max dose a hundred mg
Image: canagliflozin (Invokana) dosing
dapagliflozin (Farxiga) dosing
five to 10 mg QD
If GFR <45, see packaging
Image: dapagliflozin (Farxiga) dosing
empagliflozin (Jardiance) dosing
10 to twenty-five mg QD
If GFR <forty five, see packaging
Image: empagliflozin (Jardiance) dosing
ertugliflozin (Steglatro) dosing
5 to 15 mg QD
If GFR <60, see package insert
Image: ertugliflozin (Steglatro) dosing
five aspect outcomes of SGLT2 inhibitors
- hypotension
- UTIs
- increased urination
- genital contamination
- ketoacidosis
Cardio and renal blessings of...
- canagliflozin (Invokana)
- dapagliflozin (Farxiga)
- empagliflozin (Jardiance)
