BIOL 133 (20) Questions with CORRECT Answers
Question:
(16) A gene is made up of three exons (numbered consecutively) with two introns
(intron 1 between exons 1 and 2 and intron 2 between exons 2 and 3). What would
happen if there were a mutation at the 3' splice site of intron 1?
Answer:
mRNA with all three exons along with intron 1.
Question:
(16) Epigenetics refers to a special kind of hereditary mechanism. Epigenetic
changes do not change the DNA nucleotide sequence, yet their effect on gene
expression can last for several generations. In one surprising study, it was found
that the grandsons of men who suffered a famine were less likely to die of
cardiovascular disease. The experience of famine made some cardioprotective change
in the sperm of those grandfathers that was passed on. What type of change was
likely responsible?
Answer:
Histone acetylation or DNA methylation.
Question:
(16) Overexpression of miRNAs can lead to a decrease of protein expression
associated with some forms of cancer. What could a drug do to counter this effect?
Answer:
Decrease expression of miRNA.
Question:
(16) What would happen if there were a mutation in the operator of the trp operon?
Answer:
The trp operon would continuously express the genes.
Question:
(16) What part of the ribosome is important in catalyzing peptide bonds?
Answer:
The rRNA.
Question:
(16) A gene is made up of three exons (numbered consecutively) with two introns
(intron 1 between exons 1 and 2 and intron 2 between exons 2 and 3). What would
happen if there were a mutation at the 3' splice site of intron 1?
Answer:
mRNA with all three exons along with intron 1.
Question:
(16) Epigenetics refers to a special kind of hereditary mechanism. Epigenetic
changes do not change the DNA nucleotide sequence, yet their effect on gene
expression can last for several generations. In one surprising study, it was found
that the grandsons of men who suffered a famine were less likely to die of
cardiovascular disease. The experience of famine made some cardioprotective change
in the sperm of those grandfathers that was passed on. What type of change was
likely responsible?
Answer:
Histone acetylation or DNA methylation.
Question:
(16) Overexpression of miRNAs can lead to a decrease of protein expression
associated with some forms of cancer. What could a drug do to counter this effect?
Answer:
Decrease expression of miRNA.
Question:
(16) What would happen if there were a mutation in the operator of the trp operon?
Answer:
The trp operon would continuously express the genes.
Question:
(16) What part of the ribosome is important in catalyzing peptide bonds?
Answer:
The rRNA.
