MSN 671 Quiz 1 Study Set - Psychopharmacology I - 2026-2027 | Advanced Nursing
What effect does a drug that acts as an agonist for It would be expected to decrease the amount of norepinephrine in the synapse.
norepinephrine have on the amount of norepinephrine in
the synapse?
What are drugs that interfere with reuptake called? Agonists.
What metabolizes drugs in the liver? Cytochrome P-450 enzymes.
What is it called when a heavy drinker requires more Cross tolerance.
anesthesia than a comparable person?
What characteristic must a drug have to pass rapidly It must be highly lipid soluble.
through the capillaries surrounding the brain?
Which neurotransmitter is NOT taken back into the Acetylcholine.
presynaptic terminal via an active reuptake mechanism?
What does the therapeutic index refer to? The relative safety of the drug.
What type of kinetics does a drug have if its rate of Zero order kinetics.
metabolism is independent of its plasma concentration?
What would we expect from a drug with a high oil/water It would accumulate in the brain rapidly.
partition coefficient?
What does metabolism of a drug refer to? Detoxification.
What is the main route of excretion for drugs? Renal system.
In the simplest form, what does 'pharmacokinetics' A drug's time course.
describe?
Where do psychoactive drugs commonly depot bind? All of the above (albumin in the blood, fatty tissues, muscles).
When is a weak acid most ionized and least able to pass In a medium with a pH of 9 (basic).
through biological membranes?
How permeable are the membranes that separate fetal They are highly permeable to psychoactive drugs.
blood from maternal blood to psychoactive drugs?
, MSN 671 Quiz 1 Study Set - Psychopharmacology I - 2026-2027 | Advanced Nursing
What is the process called when the liver metabolizes a Conjugation.
drug by Glucoronic acid to the drug molecule?
What factors affect the pharmacokinetics of a drug? All of the above (genetics, physiological state, species).
What happens as the oil/water partition coefficient The drug becomes more lipid soluble.
increases?
What are arguments used to support the legalization of All of the above (it would raise tax revenue, crime would decrease, drug quality for
drugs? users would be safer).
What is a drug that binds with and activates a receptor A direct agonist.
called?
How long does it take to reach 'steady state' Achieved in approximately six times the drug's elimination half-life.
concentrations of a drug?
What does the word 'pharmakos' mean? A scapegoat.
Which brain nucleus is responsible for producing most of Raphe nuclei.
the brain serotonin?
Can a neurotransmitter bind either a fast-responding or True.
slow-responding receptor?
What does tachyphalaxis refer to? The fact that some individuals develop acute tolerance to a drug after very little
experience with the drug.
If John took a drug and 7 hours later 50% was still 7 hours.
circulating, what is the half-life of the drug?
What are the most common inhibitory and excitatory GABA and glutamate.
neurotransmitters in the brain, respectively?
What happens once a person becomes physically The person will no longer be physically dependent usually within a few weeks after
dependent on a drug? stopping administration of the drug.
What is the most dangerous mode of drug administration? Intravenous injection.
What type of drug is apomorphine, which stimulates A dopamine antagonist.
dopamine autoreceptors?
What effect does a drug that acts as an agonist for It would be expected to decrease the amount of norepinephrine in the synapse.
norepinephrine have on the amount of norepinephrine in
the synapse?
What are drugs that interfere with reuptake called? Agonists.
What metabolizes drugs in the liver? Cytochrome P-450 enzymes.
What is it called when a heavy drinker requires more Cross tolerance.
anesthesia than a comparable person?
What characteristic must a drug have to pass rapidly It must be highly lipid soluble.
through the capillaries surrounding the brain?
Which neurotransmitter is NOT taken back into the Acetylcholine.
presynaptic terminal via an active reuptake mechanism?
What does the therapeutic index refer to? The relative safety of the drug.
What type of kinetics does a drug have if its rate of Zero order kinetics.
metabolism is independent of its plasma concentration?
What would we expect from a drug with a high oil/water It would accumulate in the brain rapidly.
partition coefficient?
What does metabolism of a drug refer to? Detoxification.
What is the main route of excretion for drugs? Renal system.
In the simplest form, what does 'pharmacokinetics' A drug's time course.
describe?
Where do psychoactive drugs commonly depot bind? All of the above (albumin in the blood, fatty tissues, muscles).
When is a weak acid most ionized and least able to pass In a medium with a pH of 9 (basic).
through biological membranes?
How permeable are the membranes that separate fetal They are highly permeable to psychoactive drugs.
blood from maternal blood to psychoactive drugs?
, MSN 671 Quiz 1 Study Set - Psychopharmacology I - 2026-2027 | Advanced Nursing
What is the process called when the liver metabolizes a Conjugation.
drug by Glucoronic acid to the drug molecule?
What factors affect the pharmacokinetics of a drug? All of the above (genetics, physiological state, species).
What happens as the oil/water partition coefficient The drug becomes more lipid soluble.
increases?
What are arguments used to support the legalization of All of the above (it would raise tax revenue, crime would decrease, drug quality for
drugs? users would be safer).
What is a drug that binds with and activates a receptor A direct agonist.
called?
How long does it take to reach 'steady state' Achieved in approximately six times the drug's elimination half-life.
concentrations of a drug?
What does the word 'pharmakos' mean? A scapegoat.
Which brain nucleus is responsible for producing most of Raphe nuclei.
the brain serotonin?
Can a neurotransmitter bind either a fast-responding or True.
slow-responding receptor?
What does tachyphalaxis refer to? The fact that some individuals develop acute tolerance to a drug after very little
experience with the drug.
If John took a drug and 7 hours later 50% was still 7 hours.
circulating, what is the half-life of the drug?
What are the most common inhibitory and excitatory GABA and glutamate.
neurotransmitters in the brain, respectively?
What happens once a person becomes physically The person will no longer be physically dependent usually within a few weeks after
dependent on a drug? stopping administration of the drug.
What is the most dangerous mode of drug administration? Intravenous injection.
What type of drug is apomorphine, which stimulates A dopamine antagonist.
dopamine autoreceptors?
