Immunology Kuby Chapter 3 Receptors and Signaling: B and T-Cell Receptors exam questions and correct answers

Immunology Kuby Chapter 3 Receptors and Signaling: B and T-Cell Receptors exam questions and correct answers 1. Which of the following types of bonds would be LEAST likely in a receptor-ligand interaction? A. Ionic bond B. Covalent bond C. Hydrogen bond D. Hydrophobic interaction E. Ionic bond Answer: B Section: Receptor-Ligand Interactions Difficulty: 2 Hint: Most receptor ligand interactions can be disrupted with high salt concentrations. 2. Ka, the association constant, is a measure of which of the following? A. The concentration of unbound ligand B. The concentration of unbound receptor C. The affinity of receptor for ligand D. The size of the receptor relative to the ligand E. The number of ligands for each receptor Answer: C Section: Receptor-Ligand Interactions Difficulty: 2 Hint: It is the ratio of association rate constant over the dissociation rate constant. 3. Receptors that are multivalent tend to bind to their ligands more strongly than receptors with a single binding site. What is the term used to describe this phenomenon? A. Avidity B. Valency C. Affinity D. Magnetism E. None of the above Answer: A Section: Receptor-Ligand Interactions Difficulty: 2 Hint: Affinity is factored into the calculation for avidity. 4. Which of the following BEST describes how cytokines are released from activated T cells?