NURS 617 PHARM EXAM 1 ACTUAL TEST
PAPER COMPLETE QUESTIONS AND
SOLUTIONS TESTED ANSWERS
◉ CNS sedation and dizziness on initiation of therapy
Orthostatic hypotension
Impotence and decrease libido
Rebound hypertension upon rapid discontinuation
Bradycardia
Clonidine causes dry mouth
Answer: Some disadvantages to use of Alpha 2 agonists
Alpha methyldopa
Clonidine
Guanfacine
◉ Alpha 1 blockers
Answer: Direct antagonists on alpha 1 receptors located on the
smooth muscle cells making up the walls of the peripheral arterioles
and peripheral veins. This blocks the normal vasoconstrictive effects
of the sympathetic nervous system causing veins to become more
dilated. This results in decreased peripheral resistance and
decreased venous return therefore lowering blood pressure.
,◉ Prazosin, Doxazosin, Terazosin
Answer: Examples of Alpha 1 blockers
◉ Alpha 1 blockers (-zosins)
Answer: Which antihypertensive medication class significantly
reduces left ventricular afterload and is very effective in
management of CHF
◉ Alpha 1 blockers (-zosins)
Answer: Which antihypertensive drug class may increase the
sensitivity of insulin receptors, improving efficacy of insulin and is a
good choice for diabetics with HTN?
◉ Alpha 1 blockers (-zosins)
Answer: Antihypertensive medication that can treat both HTN and
BPH?
◉ Orthostatic hypotension
Reflex tachycardia
Impotence
Weakness, dizziness, nausea
headache
, Nasal stuffiness
Answer: Some disadvantages of the use of Alpha 1 blockers (-zosins)
◉ Adrenergic Neuron Blocers
Answer: Lower blood pressure by either directly preventing the
release of norepinephrine from sympathetic nerve endings or by
depleting the nerve endings of stored norepinephrine.
◉ Reserpine
Answer: example of adrenergic neuron blocker
◉ Slow onset of action- takes 1-2 weeks for peak effect
Dizziness, sedation
Fatigue and Lethargy
Depression and suicide
Bradycardia and CHF
Nasal stuffiness
Some cholinergic effects
Answer: Disadvantages of adrenergic neuron blockers
◉ Non selective Beta Blockers
PAPER COMPLETE QUESTIONS AND
SOLUTIONS TESTED ANSWERS
◉ CNS sedation and dizziness on initiation of therapy
Orthostatic hypotension
Impotence and decrease libido
Rebound hypertension upon rapid discontinuation
Bradycardia
Clonidine causes dry mouth
Answer: Some disadvantages to use of Alpha 2 agonists
Alpha methyldopa
Clonidine
Guanfacine
◉ Alpha 1 blockers
Answer: Direct antagonists on alpha 1 receptors located on the
smooth muscle cells making up the walls of the peripheral arterioles
and peripheral veins. This blocks the normal vasoconstrictive effects
of the sympathetic nervous system causing veins to become more
dilated. This results in decreased peripheral resistance and
decreased venous return therefore lowering blood pressure.
,◉ Prazosin, Doxazosin, Terazosin
Answer: Examples of Alpha 1 blockers
◉ Alpha 1 blockers (-zosins)
Answer: Which antihypertensive medication class significantly
reduces left ventricular afterload and is very effective in
management of CHF
◉ Alpha 1 blockers (-zosins)
Answer: Which antihypertensive drug class may increase the
sensitivity of insulin receptors, improving efficacy of insulin and is a
good choice for diabetics with HTN?
◉ Alpha 1 blockers (-zosins)
Answer: Antihypertensive medication that can treat both HTN and
BPH?
◉ Orthostatic hypotension
Reflex tachycardia
Impotence
Weakness, dizziness, nausea
headache
, Nasal stuffiness
Answer: Some disadvantages of the use of Alpha 1 blockers (-zosins)
◉ Adrenergic Neuron Blocers
Answer: Lower blood pressure by either directly preventing the
release of norepinephrine from sympathetic nerve endings or by
depleting the nerve endings of stored norepinephrine.
◉ Reserpine
Answer: example of adrenergic neuron blocker
◉ Slow onset of action- takes 1-2 weeks for peak effect
Dizziness, sedation
Fatigue and Lethargy
Depression and suicide
Bradycardia and CHF
Nasal stuffiness
Some cholinergic effects
Answer: Disadvantages of adrenergic neuron blockers
◉ Non selective Beta Blockers
