NR565 NR 565 Midterm Actual Questions and Correct Answers
Q1
Which schedule drugs can APRNs prescribe?
Answer: Varies state by state May include schedule II-V, but never schedule I
Q2
Who determines and regulates prescriptive authority?
Answer: The state's health professional board
Q3
What are the key responsibilities of prescribing?
Answer: A sound understanding of drugs and the conditions that they are used to manage
Q4
What should be used in making prescribing decisions?
Answer: Cost, follow current guidelines, availability, interactions, side effects, allergies,
hepatic/renal function,
need for monitoring, special populations
Q5
PK and PD changes in older adults and how that affects how you prescribe?
Answer: Very high risk of adverse drug reactions and drug-drug interactions
Q6
Beer's Criteria
Answer: List of potentially inappropriate medications to use in the older populations Updated
annually
Q7
Impacts/outcomes of polypharmacy?
Answer: Increased ADRs and drug-drug interactions
,Q8
What are CYP450?
Answer: Enzymes responsible for drug metabolism (biotransformation)-oxidization, reduction,
hydrolyzed to
promote renal dug excretion
Q9
What do CYP450 enzymes do?
Answer: Promote drug excretion by making them more "excretable"--hydrophilic/water soluble
and charged
(ion)
Q10
CYP450 inhibitor examples?
Answer: VISA credit card debt inhibits spending on designers like CK to look GQ
Q11
What do CYP450 inhibitors do?
Answer: Decrease the rate of metabolism Act on liver through process of inhibition
Q12
What do CYP450 inhibitors do if not used correctly?
Answer: Can lead to adverse effects and drug toxicity
Q13
What happens when someone has a poor metabolism phenotype?
Answer: Associated with accumulation of drugs in the body and they may experience drug
toxicity
Q14
What does the US FDA regulate when it comes to medications?
Answer: Regulates safety and effectiveness of drugs sold in US
Q15
Reasons for medication nonadherence?
Answer: Forgetfulness, lack of planning, cost, dissatisfaction, altered dosing
, Q16
Black Box Warnings
Answer: Strongest safety warning a drug can carry and still remain on the market
Q17
Neonate and infant drug absorption
Answer: Drug sensitivity d/t organ immaturity-increased risk of ADRs
Q18
Transdermal absorption in neonates?
Answer: Infants have thin skin with high blood flow-increased absoprtion and increased risk of
toxicity
Q19
IM absorption in neonates and infants?
Answer: Neonateabsorption is slow and erratic d/t low blood flow through muscle in first days of
life
Q20
PO absorption in neonates and infants?
Answer: Gastric emptying delayed (adult emptying by 6-8mos)
Q21
Common fears with genetic testing?
Answer: Many providers don't have knowledge/comfort to order and interpret testing
Q22
Pharmacokinetics
Answer: Study of the drug's movement throughout the body ADME-absoprtion, distribution,
metabolism,
excretion
Q23
Pharmacodynamics
Answer: Study of the biochemical and physiologic effects of drugs on the body and the molecular
mechanisms
by which those effects are produced
Q1
Which schedule drugs can APRNs prescribe?
Answer: Varies state by state May include schedule II-V, but never schedule I
Q2
Who determines and regulates prescriptive authority?
Answer: The state's health professional board
Q3
What are the key responsibilities of prescribing?
Answer: A sound understanding of drugs and the conditions that they are used to manage
Q4
What should be used in making prescribing decisions?
Answer: Cost, follow current guidelines, availability, interactions, side effects, allergies,
hepatic/renal function,
need for monitoring, special populations
Q5
PK and PD changes in older adults and how that affects how you prescribe?
Answer: Very high risk of adverse drug reactions and drug-drug interactions
Q6
Beer's Criteria
Answer: List of potentially inappropriate medications to use in the older populations Updated
annually
Q7
Impacts/outcomes of polypharmacy?
Answer: Increased ADRs and drug-drug interactions
,Q8
What are CYP450?
Answer: Enzymes responsible for drug metabolism (biotransformation)-oxidization, reduction,
hydrolyzed to
promote renal dug excretion
Q9
What do CYP450 enzymes do?
Answer: Promote drug excretion by making them more "excretable"--hydrophilic/water soluble
and charged
(ion)
Q10
CYP450 inhibitor examples?
Answer: VISA credit card debt inhibits spending on designers like CK to look GQ
Q11
What do CYP450 inhibitors do?
Answer: Decrease the rate of metabolism Act on liver through process of inhibition
Q12
What do CYP450 inhibitors do if not used correctly?
Answer: Can lead to adverse effects and drug toxicity
Q13
What happens when someone has a poor metabolism phenotype?
Answer: Associated with accumulation of drugs in the body and they may experience drug
toxicity
Q14
What does the US FDA regulate when it comes to medications?
Answer: Regulates safety and effectiveness of drugs sold in US
Q15
Reasons for medication nonadherence?
Answer: Forgetfulness, lack of planning, cost, dissatisfaction, altered dosing
, Q16
Black Box Warnings
Answer: Strongest safety warning a drug can carry and still remain on the market
Q17
Neonate and infant drug absorption
Answer: Drug sensitivity d/t organ immaturity-increased risk of ADRs
Q18
Transdermal absorption in neonates?
Answer: Infants have thin skin with high blood flow-increased absoprtion and increased risk of
toxicity
Q19
IM absorption in neonates and infants?
Answer: Neonateabsorption is slow and erratic d/t low blood flow through muscle in first days of
life
Q20
PO absorption in neonates and infants?
Answer: Gastric emptying delayed (adult emptying by 6-8mos)
Q21
Common fears with genetic testing?
Answer: Many providers don't have knowledge/comfort to order and interpret testing
Q22
Pharmacokinetics
Answer: Study of the drug's movement throughout the body ADME-absoprtion, distribution,
metabolism,
excretion
Q23
Pharmacodynamics
Answer: Study of the biochemical and physiologic effects of drugs on the body and the molecular
mechanisms
by which those effects are produced
