Chamberlain College of Nursing | BIOS 255 Anatomy and Physiology III
BIOS 255 Anatomy and Physiology III Exam 2
Comprehensive Examination 2026/2027 |
Verified Questions
Chamberlain College of Nursing | BIOS 255 Anatomy and Physiology III | University-Level Nursing Students
100 Verified Questions | 4 Core Domains | Academic Year 2026/2027
Prepared by
Chamberlain College of Nursing | BIOS 255 Anatomy and Physiology III
Examination 2 Actual Exam | Academic Year 2026/2027
BIOS 255 Anatomy and Physiology III Exam 2 Comprehensive Examination 2026/2027 | Verified Questions
,INTRODUCTION
This comprehensive examination contains exactly 100 original verified questions designed to reinforce the official
Chamberlain College of Nursing BIOS 255 Anatomy and Physiology III Examination 2 course objectives for actual
exam readiness and clinical proficiency in the 2026/2027 academic year. The questions span four core domains:
Domain 1 Cardiovascular System: Heart Structure and Function, Domain 2 Blood Vessels and Circulation, Domain
3 Lymphatic System and Immune Response, and Domain 4 Respiratory System Anatomy and Physiology. Each
question is crafted to test distinct sub-topics drawn from foundational human anatomy and physiology
methodology, enabling university-level nursing students to demonstrate structural and functional mastery of the
cardiovascular, lymphatic, immune, and respiratory systems.
ACTUAL QUESTIONS
Domain 1: Cardiovascular System: Heart Structure and Function
Question 1. The heart chamber that receives oxygenated blood from the pulmonary veins is the:
A. Right atrium
B. Left atrium
C. Right ventricle
D. Left ventricle
Correct Answer: D
Rationale: Pulmonary veins return oxygen-rich blood from the lungs to the left atrium, which then empties into
the left ventricle.
Question 2. Which valve prevents backflow of blood from the left ventricle into the left atrium?
A. Tricuspid valve
B. Pulmonary semilunar valve
C. Mitral (bicuspid) valve
D. Aortic semilunar valve
Correct Answer: B
Rationale: The mitral valve closes during ventricular systole, preventing regurgitation into the left atrium.
Question 3. The pacemaker of the heart is normally the:
A. Atrioventricular node
B. Sinoatrial node
C. Purkinje fibers
D. Bundle of His
Correct Answer: C
Rationale: The sinoatrial node spontaneously depolarizes at the highest rate and sets the rhythm of the heart
under normal conditions.
Question 4. During ventricular systole, which valves are open?
A. Atrioventricular valves
B. Semilunar valves
C. Both AV and semilunar valves
D. Neither set of valves
Correct Answer: D
Rationale: Ventricular contraction forces the semilunar valves open while the atrioventricular valves remain
closed.
Question 5. The myocardium is thickest in which chamber?
A. Right atrium
B. Left atrium
C. Right ventricle
D. Left ventricle
Correct Answer: C
Rationale: The left ventricle generates the highest pressure to drive systemic circulation and therefore has the
thickest myocardial wall.
BIOS 255 Anatomy and Physiology III Exam 2 Comprehensive Examination 2026/2027 | Verified Questions
, Question 6. Which structure delays the impulse so that the atria can complete contraction before
the ventricles begin?
A. Sinoatrial node
B. Atrioventricular node
C. Purkinje fibers
D. Internodal pathways
Correct Answer: D
Rationale: The AV node slows conduction, allowing atrial systole to finish and ventricular filling to be optimized.
Question 7. Cardiac output is defined as:
A. Heart rate multiplied by stroke volume
B. Stroke volume divided by heart rate
C. End-diastolic volume minus end-systolic volume only
D. Systolic pressure minus diastolic pressure
Correct Answer: A
Rationale: Cardiac output equals the product of heart rate and stroke volume and represents the volume of blood
ejected per minute.
Question 8. The P wave of the electrocardiogram represents:
A. Ventricular depolarization
B. Atrial depolarization
C. Ventricular repolarization
D. Atrial repolarization
Correct Answer: C
Rationale: The P wave is produced by depolarization of the atrial myocardium preceding atrial contraction.
Question 9. Frank-Starling law of the heart states that:
A. Heart rate is determined solely by the autonomic nervous system
B. Stroke volume increases as end-diastolic volume increases within physiologic limits
C. Cardiac output is independent of venous return
D. Contractility decreases with increased preload
Correct Answer: D
Rationale: Increased venous return stretches cardiac muscle fibers, enhancing the force of contraction and
thereby stroke volume.
Question 10. Which vessels supply oxygenated blood to the myocardium itself?
A. Pulmonary arteries
B. Coronary arteries
C. Coronary veins
D. Superior vena cava
Correct Answer: C
Rationale: The right and left coronary arteries arise from the ascending aorta and perfuse the myocardium.
Question 11. The chordae tendineae and papillary muscles function to:
A. Open the semilunar valves
B. Prevent prolapse of the atrioventricular valve cusps into the atria during ventricular systole
C. Generate the pacemaker potential
D. Conduct impulses through the ventricles
Correct Answer: A
Rationale: Papillary muscles contract and tense the chordae tendineae, anchoring the AV valve leaflets and
preventing regurgitation.
Question 12. The period of the cardiac cycle when all four valves are closed and ventricular volume
is constant is:
A. Ventricular ejection
B. Isovolumetric contraction (and isovolumetric relaxation)
C. Atrial systole
D. Rapid filling
BIOS 255 Anatomy and Physiology III Exam 2 Comprehensive Examination 2026/2027 | Verified Questions
BIOS 255 Anatomy and Physiology III Exam 2
Comprehensive Examination 2026/2027 |
Verified Questions
Chamberlain College of Nursing | BIOS 255 Anatomy and Physiology III | University-Level Nursing Students
100 Verified Questions | 4 Core Domains | Academic Year 2026/2027
Prepared by
Chamberlain College of Nursing | BIOS 255 Anatomy and Physiology III
Examination 2 Actual Exam | Academic Year 2026/2027
BIOS 255 Anatomy and Physiology III Exam 2 Comprehensive Examination 2026/2027 | Verified Questions
,INTRODUCTION
This comprehensive examination contains exactly 100 original verified questions designed to reinforce the official
Chamberlain College of Nursing BIOS 255 Anatomy and Physiology III Examination 2 course objectives for actual
exam readiness and clinical proficiency in the 2026/2027 academic year. The questions span four core domains:
Domain 1 Cardiovascular System: Heart Structure and Function, Domain 2 Blood Vessels and Circulation, Domain
3 Lymphatic System and Immune Response, and Domain 4 Respiratory System Anatomy and Physiology. Each
question is crafted to test distinct sub-topics drawn from foundational human anatomy and physiology
methodology, enabling university-level nursing students to demonstrate structural and functional mastery of the
cardiovascular, lymphatic, immune, and respiratory systems.
ACTUAL QUESTIONS
Domain 1: Cardiovascular System: Heart Structure and Function
Question 1. The heart chamber that receives oxygenated blood from the pulmonary veins is the:
A. Right atrium
B. Left atrium
C. Right ventricle
D. Left ventricle
Correct Answer: D
Rationale: Pulmonary veins return oxygen-rich blood from the lungs to the left atrium, which then empties into
the left ventricle.
Question 2. Which valve prevents backflow of blood from the left ventricle into the left atrium?
A. Tricuspid valve
B. Pulmonary semilunar valve
C. Mitral (bicuspid) valve
D. Aortic semilunar valve
Correct Answer: B
Rationale: The mitral valve closes during ventricular systole, preventing regurgitation into the left atrium.
Question 3. The pacemaker of the heart is normally the:
A. Atrioventricular node
B. Sinoatrial node
C. Purkinje fibers
D. Bundle of His
Correct Answer: C
Rationale: The sinoatrial node spontaneously depolarizes at the highest rate and sets the rhythm of the heart
under normal conditions.
Question 4. During ventricular systole, which valves are open?
A. Atrioventricular valves
B. Semilunar valves
C. Both AV and semilunar valves
D. Neither set of valves
Correct Answer: D
Rationale: Ventricular contraction forces the semilunar valves open while the atrioventricular valves remain
closed.
Question 5. The myocardium is thickest in which chamber?
A. Right atrium
B. Left atrium
C. Right ventricle
D. Left ventricle
Correct Answer: C
Rationale: The left ventricle generates the highest pressure to drive systemic circulation and therefore has the
thickest myocardial wall.
BIOS 255 Anatomy and Physiology III Exam 2 Comprehensive Examination 2026/2027 | Verified Questions
, Question 6. Which structure delays the impulse so that the atria can complete contraction before
the ventricles begin?
A. Sinoatrial node
B. Atrioventricular node
C. Purkinje fibers
D. Internodal pathways
Correct Answer: D
Rationale: The AV node slows conduction, allowing atrial systole to finish and ventricular filling to be optimized.
Question 7. Cardiac output is defined as:
A. Heart rate multiplied by stroke volume
B. Stroke volume divided by heart rate
C. End-diastolic volume minus end-systolic volume only
D. Systolic pressure minus diastolic pressure
Correct Answer: A
Rationale: Cardiac output equals the product of heart rate and stroke volume and represents the volume of blood
ejected per minute.
Question 8. The P wave of the electrocardiogram represents:
A. Ventricular depolarization
B. Atrial depolarization
C. Ventricular repolarization
D. Atrial repolarization
Correct Answer: C
Rationale: The P wave is produced by depolarization of the atrial myocardium preceding atrial contraction.
Question 9. Frank-Starling law of the heart states that:
A. Heart rate is determined solely by the autonomic nervous system
B. Stroke volume increases as end-diastolic volume increases within physiologic limits
C. Cardiac output is independent of venous return
D. Contractility decreases with increased preload
Correct Answer: D
Rationale: Increased venous return stretches cardiac muscle fibers, enhancing the force of contraction and
thereby stroke volume.
Question 10. Which vessels supply oxygenated blood to the myocardium itself?
A. Pulmonary arteries
B. Coronary arteries
C. Coronary veins
D. Superior vena cava
Correct Answer: C
Rationale: The right and left coronary arteries arise from the ascending aorta and perfuse the myocardium.
Question 11. The chordae tendineae and papillary muscles function to:
A. Open the semilunar valves
B. Prevent prolapse of the atrioventricular valve cusps into the atria during ventricular systole
C. Generate the pacemaker potential
D. Conduct impulses through the ventricles
Correct Answer: A
Rationale: Papillary muscles contract and tense the chordae tendineae, anchoring the AV valve leaflets and
preventing regurgitation.
Question 12. The period of the cardiac cycle when all four valves are closed and ventricular volume
is constant is:
A. Ventricular ejection
B. Isovolumetric contraction (and isovolumetric relaxation)
C. Atrial systole
D. Rapid filling
BIOS 255 Anatomy and Physiology III Exam 2 Comprehensive Examination 2026/2027 | Verified Questions
