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, Test Bank -b3Introductionb3tob3Geneticb3Analysis,b312thb3Editionb3(Griffiths,b 3 2021)
v# v#
Chapter 01: The Genetics Revolution
b3 b3 b3 b3
1. Theearly 1900s was an important period for genetics dueto which of the following major events?
b3 b3 b3 b3 v# b3 b3 b3 b3 b3 b3 b3 b3 b3
a. the rediscovery of Gregor Mendel's scientific findings
b3 b3 b3 b3 b3 v#
b. Watson and Crick solving the structure of DNA
v# v# b3 v# b3 v# b3
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore Bover
b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3
i hypothesizing that chromosomes are the hereditary elements
b3 b3 b3 b3 b3 b3 b3
e. All of the answer options are correct.
b3 b3 v# b3 b3 b3
ANSWER: e
2. A sample of normal double-
b3 b3 b3 b3
stranded DNA was found to have a guanine content of 18%. What is the expected proportion of adenine?
b3 b3 b3 v# b3 b3 b3 b3 b3 b3 b3 v# b3 b3 b3 b3 b3
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b
3. In one strand of DNA, the nucleotide sequence is 5'-
b3 b3 b3 b3 b3 b3 b3 b3 v#
ATGC-
3'. The complementary sequence in the other strand must b
b3 b3 b3 b3 b3 b3 b3 b3 b3
e
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
b3 b3 b3 b3 b3 bn b3 b3 b3 b3 b3
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e
5. Which of the following is/are TRUE about genes?
b3 b3 v# b3 b3 b3 v#
a. Genes are located on chromosomes.
b3 v# v#
b. Genes come in variants known as alleles.
b3 b3 v# b3 b3 v#
c. Genes usually encode protein products.
b3 b3 b3 b3
d. All of the answer options are correct.
b3 b3 v# b3 b3 b3
e. None of the answer options is correct.
b3 b3 b3 b3 b3 b3
ANSWER: d
1| P a g e
b3 b3 b3 b3
PlusBay.Plus
, Test Bank -b3Introductionb3tob3Geneticb3Analysis,b312thb3Editionb3(Griffiths,b 3 2021)
v# v#
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while i
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
n common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
a. less DNA than common-mouse cells.
v# b3 v# b3
b. smaller genomes than common-mouse cells. b3 b3 bn b3
c. fewer DNA molecules than common-mouse cells.
b3 b3 b3 b3 b3
d. fewer genes than common-mouse cells. b3 b3 b3 b3
e. fewer sets of chromosomes than common-mouse cells.
b3 b3 b3 b3 b3 b3
ANSWER: c
7. Which of the following is a component of DNA?
b3 b3 b3 b3 b3 v# b3 b3
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3 bn
a. It is a double-helical structure.
b3 b3 b3 b3
b. Sugar–phosphate backbone is always toward the outside of the DNA. b3 b3 v# b3 b3 b3 b3 b3 b3
c. There are two hydrogen bonds between A and Tand three hydrogen bonds between C and G.
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3 b3 v#
d. There are four types of nitrogenous bases.b3 b3 b3 v# b3 b3
e. All of the answer options are correct.
b3 b3 v# b3 b3 b3
ANSWER: e
9. Which of the following is a CORRECT representation of the central dogma?
b3 b3 b3 bn v# b3 b3 b3 b3 b3 b3
a. RNA → DNA → protein b3 b3 b3 b3
b. protein → DNA → RNA b3 b3 b3 b3
c. DNA → RNA → protein b3 b3 b3 b3
d. DNA → protein → DNA b3 b3 b3 b3
e. None of the answer options is correct.
b3 b3 b3 b3 b3 b3
ANSWER: c
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies produc
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
ed by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this mutation m
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3 b3 b3 b3
ost lik ely taken place?
b3 v#b 3 b3 b3
a. in Cindy's gametes
b3 b3
b. in the cells that should normally have given rise to Cindy's tail
b3 b3 b3 bn b3 b3 b3 b3 b3 b3 b3
c. inthe cells that should normally have given rise to Cindy's and her puppies' tails
b3 b3 b3 v# b3 b3 b3 b3 v# b3 b3 b3 b3
d. in all of Cindy's cells (including her gametes)
b3 b3 b3 b3 b3 v# b3
e. in a gamete of one of Cindy's parents
b3 b3 b3 b3 b3 b3 b3
ANSWER: a
11. Which of the following features makes a species suitable as a model organism?
b3 b3 b3 b3 b3 v# b3 b3 b3 b3 b3 b3
2| P a g e
b3 b3 b3 b3
PlusBay.Plus
, Test Bank -b3Introductionb3tob3Geneticb3Analysis,b312thb3Editionb3(Griffiths,b 3 2021)
v# v#
a. small organism b3
b. short generation time
v# b3
c. small genome b3
d. produce large number of offspring b3 b3 b3 b3
e. All of the answer options are correct.
b3 b3 v# b3 b3 b3
ANSWER: e
12. Using molecular techniques, researchers have knocked out both copies of gene G in a series of genetically
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b
i dentical mouse embryos. These mice develop normally, except for their forelimbs, which are missing sever
3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
al s mall bones. What can be concluded from the results of this experiment?
b3 b3 b3 b3 v# b3 b3 b3 b3 b3 b3 b3 b3
a. Gene G encodes a protein that is a crucial component of the forelimbs' small bones in mice.
b3 b3 b3 v# b3 b3 b3 b3 b3 b3 v# b3 b3 b3 b3 v#
b. Gene G encodes aprotein that is normally only present in the forelimb cells of developing mice.
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3
c. Gene G is necessary for proper development of the forelimbs' small bones in mice.
b3 b3 v# b3 b3 b3 b3 b3 b3 b3 v# b3 b3
d. Gene G is normally only present in the forelimb cells of developing mice.
b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3
e. Gene G is normally only transcribed in the forelimb cells of developing mice.
b3 b3 v# b3 b3 b3 b3 b3 b3 b3 b3 v#
ANSWER: c
13. Who originated the one-gene–one-enzyme hypothesis?
b3 b3 b3 b3
a. Tatum and Beadle b3 b3
b. Gregor Mendel b3
c. Watson and Crick v# b3
d. Franklin and Wilkins b3 b3
e. Hershey and Chase b3 b3
ANSWER: a
14. What are alleles?
b3 b3
a. gene variants b3
b. enzymes
c. regulatory elements b3
d. denovo mutations b3
e. quantitative trait loci b3 v#
ANSWER: a
15. Which enzyme cuts DNA at a specific location?
b3 b3 b3 b3 v# v# b3
a. polymerase
b. ligase
c. nuclease
d. allele
e. ribosome
ANSWER: c
16. Which type of mutation is a unique DNA variant that exists in a child but in neither of its parents?
b3 b3 b3 v# b3 b3 b3 b3 b3 b3 b3 v# v# v# b3 b3 b3 b3 v#
a. point mutation b3
b. de novo mutation
b3 b3
3| P a g e
b3 b3 b3 b3
PlusBay.Plus
, Test Bank -b3Introductionb3tob3Geneticb3Analysis,b312thb3Editionb3(Griffiths,b 3 2021)
v# v#
Chapter 01: The Genetics Revolution
b3 b3 b3 b3
1. Theearly 1900s was an important period for genetics dueto which of the following major events?
b3 b3 b3 b3 v# b3 b3 b3 b3 b3 b3 b3 b3 b3
a. the rediscovery of Gregor Mendel's scientific findings
b3 b3 b3 b3 b3 v#
b. Watson and Crick solving the structure of DNA
v# v# b3 v# b3 v# b3
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore Bover
b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3
i hypothesizing that chromosomes are the hereditary elements
b3 b3 b3 b3 b3 b3 b3
e. All of the answer options are correct.
b3 b3 v# b3 b3 b3
ANSWER: e
2. A sample of normal double-
b3 b3 b3 b3
stranded DNA was found to have a guanine content of 18%. What is the expected proportion of adenine?
b3 b3 b3 v# b3 b3 b3 b3 b3 b3 b3 v# b3 b3 b3 b3 b3
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b
3. In one strand of DNA, the nucleotide sequence is 5'-
b3 b3 b3 b3 b3 b3 b3 b3 v#
ATGC-
3'. The complementary sequence in the other strand must b
b3 b3 b3 b3 b3 b3 b3 b3 b3
e
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
b3 b3 b3 b3 b3 bn b3 b3 b3 b3 b3
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e
5. Which of the following is/are TRUE about genes?
b3 b3 v# b3 b3 b3 v#
a. Genes are located on chromosomes.
b3 v# v#
b. Genes come in variants known as alleles.
b3 b3 v# b3 b3 v#
c. Genes usually encode protein products.
b3 b3 b3 b3
d. All of the answer options are correct.
b3 b3 v# b3 b3 b3
e. None of the answer options is correct.
b3 b3 b3 b3 b3 b3
ANSWER: d
1| P a g e
b3 b3 b3 b3
PlusBay.Plus
, Test Bank -b3Introductionb3tob3Geneticb3Analysis,b312thb3Editionb3(Griffiths,b 3 2021)
v# v#
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while i
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
n common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
a. less DNA than common-mouse cells.
v# b3 v# b3
b. smaller genomes than common-mouse cells. b3 b3 bn b3
c. fewer DNA molecules than common-mouse cells.
b3 b3 b3 b3 b3
d. fewer genes than common-mouse cells. b3 b3 b3 b3
e. fewer sets of chromosomes than common-mouse cells.
b3 b3 b3 b3 b3 b3
ANSWER: c
7. Which of the following is a component of DNA?
b3 b3 b3 b3 b3 v# b3 b3
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3 bn
a. It is a double-helical structure.
b3 b3 b3 b3
b. Sugar–phosphate backbone is always toward the outside of the DNA. b3 b3 v# b3 b3 b3 b3 b3 b3
c. There are two hydrogen bonds between A and Tand three hydrogen bonds between C and G.
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3 b3 v#
d. There are four types of nitrogenous bases.b3 b3 b3 v# b3 b3
e. All of the answer options are correct.
b3 b3 v# b3 b3 b3
ANSWER: e
9. Which of the following is a CORRECT representation of the central dogma?
b3 b3 b3 bn v# b3 b3 b3 b3 b3 b3
a. RNA → DNA → protein b3 b3 b3 b3
b. protein → DNA → RNA b3 b3 b3 b3
c. DNA → RNA → protein b3 b3 b3 b3
d. DNA → protein → DNA b3 b3 b3 b3
e. None of the answer options is correct.
b3 b3 b3 b3 b3 b3
ANSWER: c
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies produc
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
ed by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this mutation m
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3 b3 b3 b3
ost lik ely taken place?
b3 v#b 3 b3 b3
a. in Cindy's gametes
b3 b3
b. in the cells that should normally have given rise to Cindy's tail
b3 b3 b3 bn b3 b3 b3 b3 b3 b3 b3
c. inthe cells that should normally have given rise to Cindy's and her puppies' tails
b3 b3 b3 v# b3 b3 b3 b3 v# b3 b3 b3 b3
d. in all of Cindy's cells (including her gametes)
b3 b3 b3 b3 b3 v# b3
e. in a gamete of one of Cindy's parents
b3 b3 b3 b3 b3 b3 b3
ANSWER: a
11. Which of the following features makes a species suitable as a model organism?
b3 b3 b3 b3 b3 v# b3 b3 b3 b3 b3 b3
2| P a g e
b3 b3 b3 b3
PlusBay.Plus
, Test Bank -b3Introductionb3tob3Geneticb3Analysis,b312thb3Editionb3(Griffiths,b 3 2021)
v# v#
a. small organism b3
b. short generation time
v# b3
c. small genome b3
d. produce large number of offspring b3 b3 b3 b3
e. All of the answer options are correct.
b3 b3 v# b3 b3 b3
ANSWER: e
12. Using molecular techniques, researchers have knocked out both copies of gene G in a series of genetically
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b
i dentical mouse embryos. These mice develop normally, except for their forelimbs, which are missing sever
3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3
al s mall bones. What can be concluded from the results of this experiment?
b3 b3 b3 b3 v# b3 b3 b3 b3 b3 b3 b3 b3
a. Gene G encodes a protein that is a crucial component of the forelimbs' small bones in mice.
b3 b3 b3 v# b3 b3 b3 b3 b3 b3 v# b3 b3 b3 b3 v#
b. Gene G encodes aprotein that is normally only present in the forelimb cells of developing mice.
b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3
c. Gene G is necessary for proper development of the forelimbs' small bones in mice.
b3 b3 v# b3 b3 b3 b3 b3 b3 b3 v# b3 b3
d. Gene G is normally only present in the forelimb cells of developing mice.
b3 b3 b3 b3 b3 b3 b3 b3 b3 v# b3 b3
e. Gene G is normally only transcribed in the forelimb cells of developing mice.
b3 b3 v# b3 b3 b3 b3 b3 b3 b3 b3 v#
ANSWER: c
13. Who originated the one-gene–one-enzyme hypothesis?
b3 b3 b3 b3
a. Tatum and Beadle b3 b3
b. Gregor Mendel b3
c. Watson and Crick v# b3
d. Franklin and Wilkins b3 b3
e. Hershey and Chase b3 b3
ANSWER: a
14. What are alleles?
b3 b3
a. gene variants b3
b. enzymes
c. regulatory elements b3
d. denovo mutations b3
e. quantitative trait loci b3 v#
ANSWER: a
15. Which enzyme cuts DNA at a specific location?
b3 b3 b3 b3 v# v# b3
a. polymerase
b. ligase
c. nuclease
d. allele
e. ribosome
ANSWER: c
16. Which type of mutation is a unique DNA variant that exists in a child but in neither of its parents?
b3 b3 b3 v# b3 b3 b3 b3 b3 b3 b3 v# v# v# b3 b3 b3 b3 v#
a. point mutation b3
b. de novo mutation
b3 b3
3| P a g e
b3 b3 b3 b3
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