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Test Bank for Clayton’s Basic Pharmacology for Nurses 19th Edition by Michelle Willihnganz | Questions, Answers & Rationales 2026

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Test Bank for Clayton’s Basic Pharmacology for Nurses 19th Edition by Michelle Willihnganz | Questions, Answers & Rationales 2026Prepare for nursing pharmacology examinations and NCLEX-focused review with a comprehensive test-bank resource based on Clayton’s Basic Pharmacology for Nurses, 19th Edition. The textbook is authored by Michelle J. Willihnganz, Samuel L. Gurevitz, and Bruce D. Clayton and published by Mosby/Elsevier. The 19th edition focuses on applying pharmacology principles to nursing practice, including drug actions and interactions, medication administration and safety, patient education, the nursing process, pharmacologic treatment across the lifespan, dosage concepts, and major drug classifications. Elsevier also highlights new Next Generation NCLEX (NGN)-style case studies and questions, clinical judgment practice, and updated information on newly approved and frequently prescribed medications.

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Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c c c c c c c c c 1


Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
c c c c c c c c




Clayton’sBasicPharmacology forNurses,19thEdition
c c c c c c c




MULTIPLE CHOICE c




1. Which name identifies a druglisted bythe US Food and
c c c c c c c c c c




Drug Administration (FDA)?
c c c




a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C c




The official name is the name under which a drug is listed by the
c c c c c c c c c c c c c




FDA. The brand name, or trademark, is the name given to a
c c c c c c c c c c c c




drug by its manufacturer. The nonproprietary, or generic,
c c c c c c c c




name is provided by the United States Adopted Names
c c c c c c c c c




Council.
c




DIF: Cognitive Level: Knowledge REF: p. 9 c c c c




OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care c c c c c c c c




Environment TOP: Nursing Process Step: Assessment
c CON: c c c c c




Patient Education
c c




2. Which source contains information specific to nutritional supplements?
c c c c c c c




a. USPDictionary of USAN &International Drug Names c c c c c c c




b. NaturalMedicines ComprehensiveDatabase c c c




c. United States Pharmacopoeia/National Formulary (USP NF) c c c c c




d. Drug Interaction Facts c c




ANS: C c




UnitedStates Pharmacopoeia/National Formularycontains information specificto nutritional
c c c c c c c c




supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
c c c c c c c c c c c c c c




names, pronunciation guide, and possible future FDA approved drugs; it does not include
c c c c c c c c c c c c c




nutritional supplements. Natural Medicines Comprehensive Database contains
c c c c c c c




evidence-based information onherbal medicines and herbal combination products; it does not c c c c c c c c c c c




include information specific to nutritional supplements. Drug Interaction Facts contains
c c c c c c c c c c




comprehensive information on drug interaction facts; it does not include nutritional supplements.
c c c c c c c c c c c c




DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 c c c c c




NAT: NCLEX Client Needs Category: Physiological Integrity
c c c c c c c




TOP: NursingProcess Step: Assessment
c CON: Nutrition |Patient Education c c c c c c c




3. Which drug reference contains drugmonographs that describe all drugs in a therapeutic class?
c c c c c c c c c c c c c




a. Drug Facts and Comparisons c c c




Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c c c c c c c c c

,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c c c c c c c c c 2

b. Drug Interaction Facts c c




c. Handbook on Injectable Drugs c c c




d. Martindale—TheComplete Drug Reference c c c




ANS: A c




Drug Facts and Comparisons contains drug monographs that describe all drugs in a
c c c c c c c c c c c c




therapeutic class. Monographs are formatted as tables toallow comparison ofsimilar
c c c c c c c c c c c c




products, brand names, manufacturers, cost indices, and available dosage forms Online
c c c c c c c c c c c




version is available.
c c c




DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 c c c c c c




OBJ: 3 c NAT: NCLEX Client NeedsCategory:Physiological Integrity
c c c c c c c




TOP: NursingProcess Step: Assessment
c CON: Safety|Patient Education |Clinical Judgment c c c c c c c c c c




4. Which drugreference contains monographs about virtuallyeverysingle-entitydrug available in
c c c c c c c c c c c




the United States and describes therapeutic uses of drugs, including approved and unapproved
c c c c c c c c c c c c c




uses?
c




a. Martindale: TheComplete DrugReference c c c c




b. AHFSDrug Information c c




c. Drug Reference c




d. DrugFacts and Comparisons c c c




ANS: B c




AHFS Drug Information contains monographs about virtually every single-entity drug available
c c c c c c c c c c




in the United States and describes therapeutic uses of drugs, including approved and unapproved
c c c c c c c c c c c c c c




uses.
c




DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 c c c c c c




OBJ: 3 c NAT: NCLEX Client NeedsCategory:Physiological Integrity
c c c c c c c




TOP: NursingProcess Step: Planning
c CON: Safety|Patient Education |Clinical Judgment c c c c c c c c c c




5. Which online drug reference makes available to healthcare providers and the public a
c c c c c c c c c c c c




c standard, comprehensive, up-to-datelook up and downloadable resource about medicines?
c c c c c c c c c




a. AmericanDrug Index c c




b. AmericanHospital Formulary c c




c. DailyMed
d. Drug Reference c




ANS: C c




DailyMed makes available to healthcare providers and the public astandard, comprehensive, up-
c c c c c c c c c c c c




to-date look up and downloadable resource about medicines. The American Drug Index is not
c c c c c c c c c c c c c




appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
c c c c c c c c c c c c c c




The drug reference is not appropriate for patient use.
c c c c c c c c c




DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 c c c c c c c OBJ:3 c




NAT: NCLEX Client Needs Category: Physiological Integrity
c c c c c c c




TOP: NursingProcess Step: Implementation
c c c c




CON: Safety |Patient Education |Clinical Judgment
c c c c c c c




6. Which legislation authorizes the FDA to determine the safetyof a drugbefore its marketing?
c c c c c c c c c c c c c c




a. Federal Food, Drug, and Cosmetic Act (1938) c c c c c c




b. Durham HumphreyAmendment (1952) c c c




Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c c c c c c c c c c

,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c c c c c c c c c 3

c. Controlled Substances Act (1970) c c c




d. KefauverHarris Drug Amendment (1962) c c c c




ANS: A c




The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of
c c c c c c c c c c c c c c c c




all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
c c c c c c c c c c c c c c




drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
c c c c c c c c c c c c c c c




safely without medical supervision and restricts their sale to prescription by a licensed
c c c c c c c c c c c c c




practitioner. The Controlled Substances Act addresses onlycontrolled substances and their
c c c c c c c c c c c




categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
c c c c c c c c c c c c




safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
c c c c c c c c c c c c c c c




before marketing them.
c c c




DIF: Cognitive Level: Knowledge REF: p. 5Table l.3 c c c c c c




OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
c c c c c c c




TOP: Nursing Process Step: Assessment
c c c c c




CON: Safety|Patient Education |Evidence |Health Care Law
c c c c c c c c c c




7. Which classification does meperidine (Demerol) fall under?
c c c c c c




a. I
b. II
c. III
d. IV
ANS: B c




Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
c c c c c c c c c c c c c c c c c




severepsychological and physical dependence. Schedule Idrugs havehigh potential forabuse and
c c c c c c c c c c c c c c




no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low
c c c c c c c c c c c c c c c c c




to moderate physical dependence or high psychological dependence. Schedule IV drugs have low
c c c c c c c c c c c c c




potential for abuse. Use may lead to limited physical or psychological dependence.
c c c c c c c c c c c c




DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 c c c c c




NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
c c c c c c c c c




TOP: NursingProcess Step: Assessment
c CON: Patient Education |Addiction |Pain c c c c c c c c c




8. Which action would the FDAtake to expedite drugdevelopment and approval for an outbreak of
c c c c c c c c c c c c c c c




smallpox?
c




a. List smallpox as a health orphan disease. c c c c c c




b. Omit the preclinical research phase. c c c c




c. Extend the clinical research phase. c c c c




d. Fast track the investigational drug. c c c c




ANS: D c




Once the Investigational New Drug Application has been approved, the drug can receive highest
c c c c c c c c c c c c c




priority within the agency, which is called fast tracking. A smallpox outbreak would become a
c c c c c c c c c c c c c c c




priority concern in the world. Orphan diseases are not researched in a priority manner. Preclinical
c c c c c c c c c c c c c c c




research is not omitted. Extending any phase of the research would mean alongertime to develop a
c c c c c c c c c c c c c c c c c c




vaccine. The FDAmust ensurethat all phases of the preclinical and clinical research phase have
c c c c c c c c c c c c c c c c




been completed in a safe manner.
c c c c c c




DIF: Cognitive Level: Knowledge c c REF: p. 7 c c c OBJ: 5 c




Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c c c c c c c c c c

, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c c c c c c c c c 4

NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
c c c c c c c c




TOP: Nursing Process Step: Assessment
c c c c c




CON: Health Care Law |Health Care Policy| Infection |Care Coordination
c c c c c c c c c c c c




9. Which statement is true about over-the-counter (OTC) drugs?
c c c c c c c




a. They are not listed in the USP NF. c c c c c c c




b. A prescription from a healthcare provider is needed.
c c c c c c c




c. Theyare sold without a prescription. c c c c c




d. They are known onlyby their brand names. c c c c c c c




ANS: C c




OTC medications do not require a prescription. A variety of names, both generic and trade, can be
c c c c c c c c c c c c c c c c




used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription drugs require
c c c c c c c c c c c c c c c c c




an order by a health professional who is licensed to prescribe, such as a physician, nurse
c c c c c c c c c c c c c c c c




practitioner, physician assistant, or dentist.
c c c c c




DIF: Cognitive Level: Comprehension REF: p. 2 OBJ:2 c c c c c




NAT: NCLEX Client Needs Category: Physiological Integrity
c c c c c c c




TOP: NursingProcess Step: Planning
c CON: Patient Education c c c c c




10. Which is the most authoritative reference for medications that are injected?
c c c c c c c c c c




a. Martindale:The Complete c c




b. Handbook on Injectable Drugs c c c




c. DailyMed
d. Handbookof Nonprescription Drugs c c c




ANS: B c




The Handbook on Injectable Drugs is the most comprehensive reference available on the topic of
c c c c c c c c c c c c c c




compatibilityof injectable drugs. It is a collection of monographs for more than 300 injectable
c c c c c c c c c c c c c c c




drugs that are listed alphabetically by generic name.
c c c c c c c c




DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 c c c c c




NAT: NCLEX Client Needs Category: Physiological Integrity
c c c c c c c




TOP: NursingProcess Step: Assessment
c CON: ClinicalJudgment |Safety c c c c c c c




11. Which statement is true about Lomotil? c c c c c




a. Abusepotential for this drug is low. c c c c c c




b. Psychologicaldependencyislikely. c c c




c. There is a high potential for abuse. c c c c c c




d. This drug is not a controlled substance. c c c c c c




ANS: A c




Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
c c c c c c c c c c c c c




dependence liabilitycompared with drugs in Schedule IV. Because abuse potential is low with a
c c c c c c c c c c c c c c c




Schedule V drug, a prescription maynot be required. Psychological dependencyis not likely with a
c c c c c c c c c c c c c c c c




Schedule V drug. Schedule V drugs are classified as controlled substances.
c c c c c c c c c c c




DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ:2 c c c c c c c




NAT: NCLEX Client Needs Category: Physiological Integrity
c c c c c c c




TOP: NursingProcess Step: Assessment
c CON: ClinicalJudgment |Safety|Patient Education c c c c c c c c c c

Connected book
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Michelle Willihnganz, Samuel L Gurevitz, PharmD, CGP, Bruce D. Clayton Basic Pharmacology for Nurses
Publisher: Unknown ISBN: 9780323796309 Edition: Unknown

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