KAPLAN AND SADOCK’S SYNOPSIS OF PSYCHIATRY COMPREHENSIVE EXAMINATION TEST 2026 FULL QUESTIONS AND CORRECT ANSWERS

KAPLAN AND SADOCK’S SYNOPSIS OF
PSYCHIATRY COMPREHENSIVE
EXAMINATION TEST 2026 FULL QUESTIONS
AND CORRECT ANSWERS



◉Prevalence of Vascular dementia among all patients with
dementia? (Kaplan & Sadock Synopsis, p 705). Answer: 15-30%


◉Prevalence of co-existing vascular and Alzheimer's dementia?
(Kaplan & Sadock Synopsis, p 705). Answer: 10-15%


◉Top 3 Dementias in general population older than 65? (Kaplan &
Sadock Synopsis, p 705). Answer: Alzheimer's Dementia, Vascular
Dementia, Mixed Vascular and Alzheimer's Dementia


◉German psychiatrist who first described the condition that is
marked by progressive memory loss most commonly seen in
patient's older than 65 years of age (Kaplan & Sadock Synopsis, p
705). Answer: Alois Alzheimer in year 1907

, ◉Pathologic hallmark of Alzheimer's type of Dementia (Kaplan &
Sadock Synopsis, p 705). Answer: Amyloid deposits


◉Among those with Alzheimer's type of Dementia, prevalence of
those with a family history of Alzheimer's Dementia (Kaplan &
Sadock Synopsis, p 706). Answer: 40%


◉Gene for Amyloid precursor protein is located on which
chromosome? (Kaplan & Sadock Synopsis, p 706). Answer: Long arm
of Chromosome 21


◉What is the major component of senile plaques? (Kaplan & Sadock
Synopsis, p 706). Answer: Beta A4 protein: 42-protein amino acid
peptide


◉Gene responsible for increased risk to develop Alzheimer's
Dementia (Kaplan & Sadock Synopsis, p 706). Answer: "One copy E4
Gene - 3x
Two copy E4 Gene - 8x"


◉Classic gross neuroanatomical finding for Alzheimer's disease
(Kaplan & Sadock Synopsis, p 706). Answer: Diffuse atrophy with
flatted cortical sulci and enlarged cerebral ventricles