CNOR Practice Exam Prep 2026/2027 – 150+ Questions & Answers | Perioperative Safety, Sterilization, Anesthesia, Infection Control & Surgical Nursing | CCI

The CNOR Practice Exam Prep by CCI 2026/2027 is a comprehensive 49-page question-and-answer resource containing 150+ practice questions and answers focused on perioperative nursing and operating-room practice. The document reviews patient assessment, surgical safety, anesthesia, positioning, infection prevention, sterilization, wound management, communication, documentation, emergency response, trauma, environmental safety, professional practice, and quality improvement. It is structured primarily as multiple-choice and rapid-recall questions for focused CNOR examination preparation. A major portion covers preoperative patient assessment and perioperative safety. Topics include pediatric medication sensitivity, National Patient Safety Goals, surgical checklists, informed consent and medical interpreters, herbal and medication considerations, NPO guidelines, VTE risk, intermittent pneumatic compression, active warming and hypothermia prevention, pressure-injury risk, psychosocial assessment, hair removal, skin antisepsis, surgical-site discrepancies, implant tracking, and medication labeling on the sterile field. The guide provides extensive coverage of anesthesia and perioperative emergencies, including opioid-related respiratory changes, naloxone, local anesthetic systemic toxicity and lipid emulsion, waste-anesthetic-gas scavenging, malignant hyperthermia, and dantrolene. Malignant hyperthermia review includes triggering anesthetic medications, early and late manifestations, hypercarbia, tachycardia, acidosis, dysrhythmias, jaw rigidity, temperature elevation, oxygenation, cooling, and immediate treatment actions. Airway emergencies and pediatric post-anesthesia complications are also represented. The infection prevention and sterilization material addresses airborne, droplet, contact, and standard precautions; Clostridioides difficile hand hygiene; MRSA environmental cleaning; operating-room air exchange; sterile storage; surgical hand hygiene; wound classification; and environmental disinfection. Sterilization topics include saturated steam, ethylene oxide, peracetic acid, ozone sterilization, Bowie-Dick testing, and Class I through Class VI chemical indicators, together with temperature, humidity, airflow, aeration, and storage considerations. Another high-yield section concentrates on patient positioning, transfers, radiation, lasers, and operating-room hazards. The questions review supine, Trendelenburg and reverse Trendelenburg positioning, brachial plexus injury risk, bariatric positioning considerations, patient-transfer equipment and staffing, radiation safety principles of time, distance, and shielding, lead shielding, laser nominal hazard zones, the surgical fire triangle, and management of an airway fire involving an endotracheal tube. The document also reviews surgical counts, specimens, implants, sterile technique, wound healing, and blood loss management. Topics include unreconciled counts and intraoperative radiography, immediate-use steam sterilization of implants as presented in the source, specimen transfer, maintenance of a delayed sterile field, crystalloids following intraoperative blood loss, absorbable gelatin hemostatic agents, and the inflammatory, proliferative, and remodeling phases of wound healing. Primary, secondary, and delayed primary/third-intention wound healing are differentiated. A substantial section addresses perioperative communication, handoffs, documentation, and postoperative care. The material covers communication breakdowns as contributors to sentinel events, read-back communication, standardized patient-information transfer, multidisciplinary handoff processes, SBAR, medical-record corrections, HITECH, patient identification, transfer from Phase I to Phase II recovery, opioid discharge education, and postoperative follow-up calls. Simulation is also identified in the document as a teaching approach for improving communication and teamwork. The later questions extend into trauma, disaster preparedness, emergency surgery, and evidence preservation, including triage decision schemes, massive hemorrhage, CT and FAST concepts, disaster drills, anthrax precautions, blast injuries, and preservation of forensic evidence. The final section examines professional perioperative nursing practice, including delegation and accountability, healthcare industry representatives, product standardization, Just Culture, evidence-based practice, sentinel events, lifelong learning, the nursing Code of Ethics, collaboration, continuing education, outcomes research, fidelity, and The Joint Commission. Academic and Exam Relevance This resource is particularly relevant to registered nurses preparing for the CNOR certification examination and perioperative nurses seeking concentrated operating-room review. Its content spans patient safety, assessment, positioning, aseptic practice, sterilization, anesthesia complications, emergency response, communication, professional accountability, and perioperative clinical practice, making it useful for both practice-question review and identification of subjects requiring further study. Relevant students: CNOR candidates, perioperative registered nurses, operating room nurses, surgical nurses, circulating nurses, perioperative nurse residents, perioperative nursing students, RN surgical-services staff, nurses preparing for CCI certification, and learners reviewing anesthesia safety, sterilization, surgical infection prevention, patient positioning, wound management, trauma, and perioperative professional practice. Primary professional reference: Competency & Credentialing Institute (CCI), CNOR certification and examination-preparation resources. Supporting professional references: Association of periOperative Registered Nurses (AORN), Guidelines for Perioperative Practice; The Joint Commission, National Patient Safety Goals. These references are particularly relevant for checking current standards because perioperative recommendations and safety requirements can change over time. 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