PREMIUM ORIGINAL PHARMACOLOGY STUDY & PRACTICE GUIDE
Mechanism-Based Therapeutics • Exam-Focused Q&A; • Clinical Reasoning • Memory Aids
Source note: The linked Stuvia listing is a 99-page paid test-bank document. The publisher's 6th-edition information identifies a 712-page
textbook organized around pharmacodynamics, pharmacokinetics, pharmacogenomics, drug development, autonomic pharmacology, CNS
therapy and additional system-based therapeutic sections. This guide is independently authored from those public topic areas and standard
pharmacology knowledge. It does not reproduce or reconstruct the paid test bank, and the questions are not represented as
publisher-supplied or verified exam questions.
Brody's Human Pharmacology 6e — Independent Study Resource Page 1
, 1. FOUNDATIONS, PHARMACODYNAMICS & PHARMACOKINETICS
Question 1: What is pharmacology?
A. Study of drugs and their effects on living systems
B. Study of anatomy only
C. Study of surgery
D. Study of nutrition only
Correct Answer: A
Rationale: Pharmacology examines drugs, their actions, therapeutic uses, adverse effects and interactions.
Question 2: Pharmacodynamics describes:
A. What the drug does to the body
B. What the body does to the drug
C. Drug manufacturing only
D. Drug pricing
Correct Answer: A
Rationale: Pharmacodynamics includes drug targets, receptor interactions, dose-response relationships and physiologic effects. PD =
Pharmacodynamics = Drug → patient.
Question 3: Pharmacokinetics describes:
A. What the body does to the drug
B. What the drug does to the receptor only
C. Drug naming
D. Prescription law
Correct Answer: A
Rationale: Absorption, distribution, metabolism and excretion determine drug concentrations over time. PK = body processes the drug:
ADME.
Question 4: A drug's half-life is the time required for:
A. Plasma concentration to decrease by approximately 50%
B. The drug to become 100% effective
C. Absorption to reach zero in every case
D. A prescription to expire
Correct Answer: A
Rationale: Half-life is a concentration-time concept and helps determine dosing intervals and time to steady state.
Question 5: Bioavailability refers to:
A. Fraction of administered drug reaching systemic circulation unchanged
B. Total dose prescribed
C. Drug color
D. Protein binding only
Correct Answer: A
Rationale: Bioavailability is affected by route and processes such as incomplete absorption and first-pass metabolism. IV administration has
essentially complete systemic bioavailability.
Brody's Human Pharmacology 6e — Independent Study Resource Page 2