Answers 2026/2027 Grand canyon university
Q1. Which statement best describes pharmacokinetics?
A. What the drug does to the body
B. What the body does to the drug
C. How drugs are named
D. How medications are prescribed
Correct Answer: B
Rationale: Pharmacokinetics describes absorption, distribution, metabolism,
and excretion of medications by the body.
Q2. Which statement best describes pharmacodynamics?
A. What the drug does to the body
B. How the kidneys eliminate medications
C. How medications are absorbed
D. How drugs are packaged
Correct Answer: A
Rationale: Pharmacodynamics concerns drug actions, mechanisms, and
effects on the body.
**Q3. Which organ is the primary site of metabolism for many medications?
A. Liver
B. Heart
C. Spleen
D. Bladder
Correct Answer: A
Rationale: Hepatic enzymes metabolize many medications and can convert
drugs into active or inactive metabolites.
**Q4. Which laboratory value is commonly used to assess renal function?
A. Creatinine
B. ALT
C. AST
D. Bilirubin
Correct Answer: A
, Rationale: Serum creatinine is commonly used to evaluate kidney function
and medication clearance.
**Q5. A client has significant renal impairment. What can happen to a
medication primarily eliminated by the kidneys?
A. The medication may accumulate.
B. The medication will always be eliminated faster.
C. The medication will immediately become inactive.
D. The medication cannot enter the bloodstream.
Correct Answer: A
Rationale: Reduced renal clearance can prolong drug elimination and
increase serum concentrations.
**Q6. What does a medication's half-life represent?
A. Time required for the drug amount or concentration to decrease by 50%
B. Time required to reach its maximum effect
C. Time required to begin absorption
D. Time required to eliminate 100% of the medication
Correct Answer: A
Rationale: Half-life is the time required for the amount or concentration of a
drug in the body to decrease by one-half.
**Q7. What is a narrow therapeutic index?
A. A small difference between therapeutic and toxic drug concentrations
B. A medication that has no adverse effects
C. A medication that is ineffective at low doses
D. A drug that is never monitored
Correct Answer: A
Rationale: Drugs with a narrow therapeutic index have a relatively small
margin between an effective concentration and a toxic concentration.
**Q8. Which medications are examples of drugs with narrow therapeutic
ranges?
A. Digoxin and phenytoin
B. Acetaminophen and saline
C. Amoxicillin and vitamin C
D. Calcium carbonate and antacids