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Pharmacology Test Bank 2026: 500+ NCLEX Practice Questions & Answers | Guaranteed Pass

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Master nursing pharmacology for the 2026 NCLEX! This comprehensive test bank covers pharmacokinetics, drug classifications, and patient safety. Includes hundreds of practice questions, detailed rationales, and NGN-style case studies. Ace your exam with this A+ graded review.

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Pharmacology Exam 1 Overview of
2026\2027 with 100% questions and
answers |highly graded a+

Tolerance
(definition) - CORRECT ANSWERS-the need for higher doses to produce response

Addiction
(definition) - CORRECT ANSWERS-use despite harm; psychological "craving," and
display of addictive (drug seeking) behaviors

Physical Dependence
(definition) - CORRECT ANSWERS-withdrawal symptoms elicited upon discontinuation

Drugs that affect GABA - CORRECT ANSWERS-Ethanol
Benzodiazepines
Barbiturates
Non-Benzodiazapine sedative-hypnotics (hypnotics in general)
Chloral hydrate

What effect does ethanol have on the heart? - CORRECT ANSWERS-depresses
myocardial contractility

What effect does Ethanol have on smooth muscle? - CORRECT ANSWERS-
vasodilation in the periphery

What are some therapeutic benefits and possible uses of ethanol? - CORRECT
ANSWERS-Self-treatment of anxiety
depression
Essential tremor

Short-acting benzodiazapines - CORRECT ANSWERS-Alprazolam
triazolam

Intermediate-acting benzodiazapines - CORRECT ANSWERS-Clonazepam
lorazepam

, Long-acting benzodiazapines - CORRECT ANSWERS-Diazepam
flurazepam

Most commonly used benzodiazapines - CORRECT ANSWERS-Alprazolam (Xanax)
Lorazepam (Ativan)
Diazepam (Valium)

Short acting barbiturates - CORRECT ANSWERS-Pentobarbital (Nembutal)

Intermediate acting barbiturates - CORRECT ANSWERS-Butabarbital (butisol)

Long acting Barbiturates - CORRECT ANSWERS-Phenobarbital (Luminal)

Adverse effects of Barbiturates - CORRECT ANSWERS-Residual effects (hangover)

Anterograde amnesia
(Which may exacerbate current issues memory loss/cognition in elderly patients)

Tolerance/Dependence

Complex behaviors (sleep walking, eating, driving)

Give an example of a non-benzodiazepine, Non-barbiturate sedative/hypnotic -
CORRECT ANSWERS-Chloral Hydrate

Examples of Antihistamines - CORRECT ANSWERS-Diphenhydramine (Benadryl)
Hydroxyzine (Atarax)
Promethazine (Phenergan)

Examples of antidepressants - CORRECT ANSWERS-Tricyclic Antidepressants:
Amitriptyline (Elavil)

Trazodone (Desyrel)

Examples of Antipsychotics - CORRECT ANSWERS-Quetiapine (Seroquel)

Centrally-acting muscle relaxants - CORRECT ANSWERS-Benzodiazepines
Baclofen
Cyclobenzaprine
Carisoprodol
Methocarbamol

Agents for Spasticity - CORRECT ANSWERS-Baclofen (Lioresal)
Tizanidine (Zanaflex)

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