Applied Pathophysiology for the Advanced Practice Nurse 2nd Edition

Applied Pathophysiology for the Advanced Practice Nurse 2nd Edition -
Chapter 3 Questions And Answers 2025\2026




With the exception of the first two steps, what is required in all steps of the clotting process?



A) Calcium

B) Prothrombin

C) Tissue factor

D) Plasminogen - CORRECT ANSWER-A) Calcium



The first step of hemostasis occurs as a:

A) fibrin clot.

B) platelet plug.

C) clot retraction.

D) vessel spasm. - CORRECT ANSWER-D) vessel spasm.



To form a platelet plug, platelets are attracted to the damaged vessel, and then platelet ____
occurs.

A) adhesion

B) fibrinolysis

C) thrombosis

D) thromboxane A2 - CORRECT ANSWER-A) adhesion

, Blood coagulation is initiated by either of two pathways. The intrinsic pathway requires
circulating ____ to begin the step-wise coagulation cascade.

A) protein C

B) thrombin

C) factor XII

D) tissue factor - CORRECT ANSWER-C) factor XII



Increased platelet function, and consequent hypercoagulability, can be caused by:

A) factor V mutation.

B) platelet insensitivity.

C) vascular wall damage.

D) decreased platelet numbers. - CORRECT ANSWER-C) vascular wall damage.



Immune thrombocytopenia purpura (ITP) is a/an ____ disorder that destroys ____.

A) allergic; fibrinogen

B) alloimmune; factor VIII

C) autoimmune; platelets

D) immunoglobulin; B cells - CORRECT ANSWER-C) autoimmune; platelets



Thrombotic thrombocytopenic purpura (TTP) causes which of the following manifestations?
Select all that apply.

A) Purpura

B) Jaundice

C) Petechiae

D) Erythema

E) Confusion - CORRECT ANSWER-A) Purpura

C) Petechiae