ADVANCED PHARMACOLOGY AND EXAM 1 UPDATED
ACTUAL QUESTIONS AND CORRECT ANSWERS
Question:
ADVANCED PHARMACOLOGY/
QUESTIONS AND CORRECT
Body increases # of receptors in response to
blockers)
-May cause increase in symptoms if stopped
Down-regulation
1
Answer:
EXAM 1 UPDATED ACTUAL
ANSWERS
, medication's blocking them (ex: beta
suddenly (HTN, heartburn)
Distribution
2
Question:
Liberation, Absorption, Distribution, Metabolism,
Elimination, Therapeutic drug monitoring
Answer:
Basic pharmacokinetics (LADMET)
Question:
Name brand vs. generic/ 2 different drugs have the same
form and concentration Within -20 to 25%
Answer:
Bioequivalence
Question:
-Applies to most drugs
-Takes the same amount of time to wear off, regardless of
amount
-Dose INDEPENDENT
Answer:
First order kinetics
Question:
-Dose DEPENDENT kinetics
Funnel example/Time it takes to wear off depends on
amount taken (Ex: ETOH)
Answer:
Zero-order kinetics
Question:
-Absorption/Elimination are equal (Reaches a plateau)
-Dependent on elimination half-life (Does not depend on
loading doses or interval)
Answer:
Steady State
Question:
Depends on:
-Rate: T-max
-Extent: C-max/AUC
-Bioavailability: Amt. of drug that reaches circulation
(First-pass effect) (Route of admin.)
Answer:
Absorption
ACTUAL QUESTIONS AND CORRECT ANSWERS
Question:
ADVANCED PHARMACOLOGY/
QUESTIONS AND CORRECT
Body increases # of receptors in response to
blockers)
-May cause increase in symptoms if stopped
Down-regulation
1
Answer:
EXAM 1 UPDATED ACTUAL
ANSWERS
, medication's blocking them (ex: beta
suddenly (HTN, heartburn)
Distribution
2
Question:
Liberation, Absorption, Distribution, Metabolism,
Elimination, Therapeutic drug monitoring
Answer:
Basic pharmacokinetics (LADMET)
Question:
Name brand vs. generic/ 2 different drugs have the same
form and concentration Within -20 to 25%
Answer:
Bioequivalence
Question:
-Applies to most drugs
-Takes the same amount of time to wear off, regardless of
amount
-Dose INDEPENDENT
Answer:
First order kinetics
Question:
-Dose DEPENDENT kinetics
Funnel example/Time it takes to wear off depends on
amount taken (Ex: ETOH)
Answer:
Zero-order kinetics
Question:
-Absorption/Elimination are equal (Reaches a plateau)
-Dependent on elimination half-life (Does not depend on
loading doses or interval)
Answer:
Steady State
Question:
Depends on:
-Rate: T-max
-Extent: C-max/AUC
-Bioavailability: Amt. of drug that reaches circulation
(First-pass effect) (Route of admin.)
Answer:
Absorption
