NR 283 PATHOPHYSIOLOGY ACTUAL
EXAM PAPER 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
●● Pathogenesis. Answer: Story of how disease develops
●● Atrophy. Answer: Decrease in the size of the cells, results in reduced
tissue mass
●● Hypertrophy. Answer: Increase in cell size, results in enlarged tissue
mass
●● Hyperplasia. Answer: Increased number of cells, results in enlarged
tissue mass
●● Metaplasia. Answer: Mature cell type is replaced by a different
mature cell type, Ex: chronic smokers, cells lose cilia
●● Dysplasia. Answer: Cells are different looking varying in size and
shape
●● Neoplasia. Answer: New growth, commonly a tumor. May be
malignant or benign
, ●● Apoptosis. Answer: Programmed cell death, normal occurrence in
the body
●● Ischemia. Answer: Deficit of oxygen in the cells
●● Hypoxia. Answer: Reduced oxygen in the tissues
●● Iatrogenic. Answer: illness or disease process because a medical
process was done ex: CAUTI
●● Autosomal Recessive Disorders. Answer: Has to have two recessive
genes to have disease, only one recessive gene to be carrier ex: Cystic
fibrosis, PKU (phenylketonuria), Tay-Sachs
●● Cystic fibrosis. Answer: autosomal recessive disorder that causes
thick mucous secretions
●● PKU (phenylketonuria). Answer: autosomal recessive disorder that
causes an inability to metabolize phenylalanine. Can cause mental
retardation. Pt must follow strict very low protein diet
EXAM PAPER 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
●● Pathogenesis. Answer: Story of how disease develops
●● Atrophy. Answer: Decrease in the size of the cells, results in reduced
tissue mass
●● Hypertrophy. Answer: Increase in cell size, results in enlarged tissue
mass
●● Hyperplasia. Answer: Increased number of cells, results in enlarged
tissue mass
●● Metaplasia. Answer: Mature cell type is replaced by a different
mature cell type, Ex: chronic smokers, cells lose cilia
●● Dysplasia. Answer: Cells are different looking varying in size and
shape
●● Neoplasia. Answer: New growth, commonly a tumor. May be
malignant or benign
, ●● Apoptosis. Answer: Programmed cell death, normal occurrence in
the body
●● Ischemia. Answer: Deficit of oxygen in the cells
●● Hypoxia. Answer: Reduced oxygen in the tissues
●● Iatrogenic. Answer: illness or disease process because a medical
process was done ex: CAUTI
●● Autosomal Recessive Disorders. Answer: Has to have two recessive
genes to have disease, only one recessive gene to be carrier ex: Cystic
fibrosis, PKU (phenylketonuria), Tay-Sachs
●● Cystic fibrosis. Answer: autosomal recessive disorder that causes
thick mucous secretions
●● PKU (phenylketonuria). Answer: autosomal recessive disorder that
causes an inability to metabolize phenylalanine. Can cause mental
retardation. Pt must follow strict very low protein diet