BCH 361 EXAM 4 CLICKER UPDATED ACTUAL
QUESTIONS AND CORRECT ANSWERS
Question:
1. Why is the conversion of pyruvate to acetyl CoA a
decisive step in metabolism in animals?
Answer:
Animals cannot convert acetyl CoA back to glucose
Question:
2. Pyruvate dehydrogenase directly connects the following
two metabolic pathways:
Answer:
glycolysis and the citric acid cycle
Question:
3. This enzyme occupies the central position in the multi-
enzyme pyruvate dehydrogenase complex:
Answer:
dihydrolipoyl transacetylase
Question:
4. The lipoamide swinging arm is attached to this enzyme in
the PDH complex:
Answer:
dihydrolipoyl transacetylase
Question:
5. Conversion of dihydrolipoamide to lipoamide occurs at
this enzyme in the PDH complex:
Answer:
dihydrolipoyl dehydrogenase
Question:
6. This acetyl group is transferred to lipoamide in this
enzyme of the PDH complex:
Answer:
pyruvate dehydrogenase component
, Question:
7. With of these compounds is a stoichiometric coenzyme
for pyruvate dehydrogenase?
Answer:
CoA
Question:
8. Acetyl CoA is an important molecule in metabolic
pathways because:
Answer:
it contains a high energy thioester bond that can be used to drive chemical
reactions
Question:
9. Phosphorylation of the pyruvate dehydrogenase
complex:
Answer:
increases its catalytic activity
Question:
10. Acetyl CoA interacts with this PDH enzyme to inhibit PDH
complex activity:
Answer:
dihydrolipoyl transacetylase
Question:
11. In the first stage of the citric acid cycle, how many
carbon atoms are lost as carbon dioxide for each
molecule of citrate?
Answer:
2
Question:
12. By the end of the second stage of the citric acid cycle,
succinyl CoA has been converted into this 4-carbon
compound:
Answer:
oxaloacetate
QUESTIONS AND CORRECT ANSWERS
Question:
1. Why is the conversion of pyruvate to acetyl CoA a
decisive step in metabolism in animals?
Answer:
Animals cannot convert acetyl CoA back to glucose
Question:
2. Pyruvate dehydrogenase directly connects the following
two metabolic pathways:
Answer:
glycolysis and the citric acid cycle
Question:
3. This enzyme occupies the central position in the multi-
enzyme pyruvate dehydrogenase complex:
Answer:
dihydrolipoyl transacetylase
Question:
4. The lipoamide swinging arm is attached to this enzyme in
the PDH complex:
Answer:
dihydrolipoyl transacetylase
Question:
5. Conversion of dihydrolipoamide to lipoamide occurs at
this enzyme in the PDH complex:
Answer:
dihydrolipoyl dehydrogenase
Question:
6. This acetyl group is transferred to lipoamide in this
enzyme of the PDH complex:
Answer:
pyruvate dehydrogenase component
, Question:
7. With of these compounds is a stoichiometric coenzyme
for pyruvate dehydrogenase?
Answer:
CoA
Question:
8. Acetyl CoA is an important molecule in metabolic
pathways because:
Answer:
it contains a high energy thioester bond that can be used to drive chemical
reactions
Question:
9. Phosphorylation of the pyruvate dehydrogenase
complex:
Answer:
increases its catalytic activity
Question:
10. Acetyl CoA interacts with this PDH enzyme to inhibit PDH
complex activity:
Answer:
dihydrolipoyl transacetylase
Question:
11. In the first stage of the citric acid cycle, how many
carbon atoms are lost as carbon dioxide for each
molecule of citrate?
Answer:
2
Question:
12. By the end of the second stage of the citric acid cycle,
succinyl CoA has been converted into this 4-carbon
compound:
Answer:
oxaloacetate