BIOM 3090 MIDTERM UPDATED ACTUAL QUESTIONS
AND CORRECT ANSWERS
Question:
1. and CORRECT Answers
Answer:
,Question:
2. problem for drugs since body is made
to be resistant to foreign substances?
Answer:
they'll only be effective when they cross physiological
barriers, limits bioavailability
Question:
3. how the body affects a specific drug after admin
through absorption and distribution
Answer:
Pharmacokinetics
Question:
4. overall pathway of drugs in the body?
Answer:
absorption (by passing barriers) -> distribution
through body (ex. blood) -> metabolism (inactivate
drug w/ enzymes) -> excretion/elimination
Question:
5. hippocrates and galen view of universe
(what its made of)
- how did they relate this to the body?
- what were the elements related to
(what humour)
Answer:
- earth, wind, fire, water
- thought each element corresponds to a humour in
the body
- wind=blood (hot & moist), water=phlegm (cold &
moist), fire=yellow bile (hot & dry), earth=black bile
(cold & dry)
, Question:
6. origins of medicine in china
what were moral 'phases' related to?
Answer:
high shade=cold illness
high wind=disorder of extremities
high dark=disorder of mental confusion
high sunshine=hot illness
high rain=ab disorders
high light=disorder of heart & mind
Question:
7. bloodletting
Answer:
bled patients w/ pneumonia (w/ leeches)
-thought it worked in saving lives, but it was just body
healing itself
Question:
8. Bioavailability
Answer:
fraction of administered drug that reaches systemic
circulation
Question:
9. Bioavailability formula
Answer:
bioavailability = quantity of drug reaching circulation /
quantity of total drug admin
Question:
10. what happens if drug is too
acidic/basic?
what happens if drug isnt acidic/basic
enough?
so what do drugs need to be in?
Answer:
- cant cross membrane and leave digestive tract
- wont dissolve well, not carried efficiently in blood
- weak acids or bases
AND CORRECT ANSWERS
Question:
1. and CORRECT Answers
Answer:
,Question:
2. problem for drugs since body is made
to be resistant to foreign substances?
Answer:
they'll only be effective when they cross physiological
barriers, limits bioavailability
Question:
3. how the body affects a specific drug after admin
through absorption and distribution
Answer:
Pharmacokinetics
Question:
4. overall pathway of drugs in the body?
Answer:
absorption (by passing barriers) -> distribution
through body (ex. blood) -> metabolism (inactivate
drug w/ enzymes) -> excretion/elimination
Question:
5. hippocrates and galen view of universe
(what its made of)
- how did they relate this to the body?
- what were the elements related to
(what humour)
Answer:
- earth, wind, fire, water
- thought each element corresponds to a humour in
the body
- wind=blood (hot & moist), water=phlegm (cold &
moist), fire=yellow bile (hot & dry), earth=black bile
(cold & dry)
, Question:
6. origins of medicine in china
what were moral 'phases' related to?
Answer:
high shade=cold illness
high wind=disorder of extremities
high dark=disorder of mental confusion
high sunshine=hot illness
high rain=ab disorders
high light=disorder of heart & mind
Question:
7. bloodletting
Answer:
bled patients w/ pneumonia (w/ leeches)
-thought it worked in saving lives, but it was just body
healing itself
Question:
8. Bioavailability
Answer:
fraction of administered drug that reaches systemic
circulation
Question:
9. Bioavailability formula
Answer:
bioavailability = quantity of drug reaching circulation /
quantity of total drug admin
Question:
10. what happens if drug is too
acidic/basic?
what happens if drug isnt acidic/basic
enough?
so what do drugs need to be in?
Answer:
- cant cross membrane and leave digestive tract
- wont dissolve well, not carried efficiently in blood
- weak acids or bases
