NURS 6052 – ESSENTIALS OF EVIDENCE-BASED
PRACTICE Comprehensive Examination: 200
Questions with Evidence-Based Rationales - Essentials
of Evidence-Based Practice: Comprehensive Mastery
Examination with 200 Questions Covering Research
Methodology, Evidence Appraisal, Implementation
Science, and Clinical Decision-Making
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NURS 6052-EBP-EXAM-200Q-2026
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TITLE: NURS 6052 – Essentials of Evidence-Based Practice:
Comprehensive 200-Question Examination with Color-Coded Answer Key
and Evidence-Based Rationales
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QUESTION TYPES: Multiple Choice | Select-All-That-Apply | True/False |
Case Studies | Scenario-Based Questions
FORMAT: Blue Questions | Red Answers | Purple Rationales
LEVEL: Graduate/Master's Nursing
TOTAL QUESTIONS: 200
ESTIMATED COMPLETION TIME: 3-4 Hours
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CONTENT DOMAINS:
Domain 1: PICOT & Clinical Question Development ............ 10 Q (5%)
Domain 2: Evidence Hierarchies & Levels .................... 20 Q (10%)
Domain 3: Research Design & Methodology .................... 30 Q (15%)
Domain 4: Biostatistics & Interpretation ................... 30 Q (15%)
Domain 5: Critical Appraisal of Evidence ................... 20 Q (10%)
, NURS 6052
Domain 6: EBP Models & Frameworks .......................... 20 Q (10%)
Domain 7: Implementation Science & Change .................. 20 Q (10%)
Domain 8: Qualitative Research Methods ..................... 16 Q (8%)
Domain 9: Systematic Reviews & Meta-Analysis ............... 14 Q (7%)
Domain 10: Clinical Translation & Decision-Making .......... 20 Q (10%)
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COPYRIGHT: All rights reserved. For educational purposes only.
Unauthorized reproduction or distribution is prohibited.
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, NURS 6052
NURS 6052 – Essentials of Evidence-Based Practice
Comprehensive Examination
QUESTION 1
QUESTION:
A nurse researcher is designing a study to examine the effectiveness of a new fall prevention
protocol in hospitalized elderly patients. Which of the following represents the most appropriate
PICOT question format for this study?
A. In hospitalized elderly patients, how does the new fall prevention protocol compare to standard
care in reducing fall rates over a 6-month period?
B. What is the effectiveness of fall prevention protocols in hospitalized patients?
C. How do elderly patients perceive the new fall prevention protocol?
D. Does the new fall prevention protocol work better than no protocol?
ANSWER:
A. In hospitalized elderly patients, how does the new fall prevention protocol compare to standard
care in reducing fall rates over a 6-month period?
RATIONALE:
Option A is correct because it contains all five PICOT elements: Population (hospitalized elderly
patients), Intervention (new fall prevention protocol), Comparison (standard care), Outcome
(reducing fall rates), and Time (6-month period). Option B lacks comparison, time, and specific
outcome. Option C addresses a qualitative question rather than an intervention effectiveness
question. Option D lacks specificity in population, comparison, and timeframe.
QUESTION 2
QUESTION:
A systematic review of randomized controlled trials (RCTs) on diabetes self-management education
would be classified as which level of evidence according to the traditional evidence hierarchy?
A. Level I
B. Level II
C. Level III
D. Level IV
ANSWER:
A. Level I
RATIONALE:
The traditional evidence hierarchy places systematic reviews and meta-analyses of RCTs at Level I,
representing the highest level of evidence. Level II includes individual RCTs; Level III includes quasi-
experimental designs; Level IV includes nonexperimental studies. The systematic review synthesizes
multiple RCTs, providing the strongest evidence for practice decisions.
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QUESTION 3
QUESTION:
A nurse is appraising a qualitative research study exploring the lived experiences of cancer survivors.
Which criterion would be most appropriate for evaluating the trustworthiness of this study?
A. Internal validity
B. Statistical significance
C. Credibility
D. Generalizability
ANSWER:
C. Credibility
RATIONALE:
Credibility is the qualitative parallel to internal validity and is a key criterion for establishing
trustworthiness in qualitative research. It addresses whether the findings accurately represent
participants' experiences. Internal validity and statistical significance relate to quantitative research,
while generalizability applies to quantitative studies with large, representative samples.
QUESTION 4
QUESTION:
Which of the following represents a barrier to evidence-based practice implementation at the
organizational level?
A. Lack of individual research skills
B. Insufficient time during shifts to read research
C. Inadequate organizational support and resources
D. Personal resistance to change
ANSWER:
C. Inadequate organizational support and resources
RATIONALE:
Organizational-level barriers include lack of administrative support, inadequate resources, absence
of evidence-based practice mentors, and lack of access to databases. Options A, B, and D represent
individual-level barriers. Understanding the level at which barriers exist is crucial for developing
targeted implementation strategies.
QUESTION 5
QUESTION:
A nurse researcher calculates a p-value of 0.03 when comparing two treatment groups. The alpha
level was set at 0.05. Which of the following statements is correct?
A. The null hypothesis should be accepted
B. The results are not statistically significant