WGU D115 OA Advanced Pathophysiology Exam (Latest 2026 / 2027) Actual Questions with Detailed Answers and OA Readiness Practice Exam Test Bank with Study Guide

WGU D115 e




WGU D115 OA Advanced Pathophysiology Exam (Latest 2026 /
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e 2027) Actual Questions with Detailed Answers and OA Readiness
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e Practice Exam Test Bank with Study Guide
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Testbankscove

,Question 1 e




In which two conditions are chromosomal abnormalities the leading known cause?
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A. Autoimmune disorders and infectious diseases e e e e




B. Respiratory infections and skin conditions e e e e




C. Intellectual disability and fetal miscarriage e e e e




D. Cardiovascular disease and type 2 diabetes e e e e e




Answer: C e




Rationale: Chromosomal abnormalities are the leading known cause of intellectual
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e disability and fetal miscarriage. Chromosomal disorders result from errors in cell division
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e that affect the number or structure of chromosomes.
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Question 2 e




Which illness is the most common cause of aplastic anemia?
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A. Type A influenza virus
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B. Chronic myeloid leukemia e e




C. Varicella zoster e




D. Human parvovirus B19 e e




Answer: D e




Rationale: Human parvovirus B19 infection may lead to the cessation of red blood cell
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e production, resulting in aplastic anemia. The virus infects and destroys erythroid
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e progenitor cells in the bone marrow. e e e e e




Question 3 e




What are three characteristics of celiac disease?
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A. Vitamin deficiencies due to damaged intestinal villi
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B. Anemia of chronic disease/poor iron absorption
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,C. Diminished growth in children e e e




D. Complete recovery with continued gluten ingestion
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Answer: A, B, C e e e




Rationale: Celiac disease damages intestinal villi, leading to malabsorption of vitamins
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and minerals. This results in vitamin deficiencies, anemia (from poor iron absorption),
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and diminished growth in children.
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Question 4 e




Which condition is cyanosis followed by rubor and paresthesias in the digits associated
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e with?

A. Systemic lupus erythematosus e e




B. Deep vein thrombosis e e




C. Raynaud phenomenon e




D. Peripheral artery disease e e




Answer: C e




Rationale: Raynaud phenomenon affects the small vessels supplying blood to the fingers
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and toes. Vasoconstriction produces cyanosis, followed by rubor (redness) and
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e paresthesias (numbness/tingling) in the digits as blood flow returns.
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Question 5 e




Describe what caused the pain that sent the patient to the emergency department with
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renal calculi.
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A. At least one renal calculus was obstructing the ureter
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B. Damage to the glomerular filtration barrier
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C. Blockage in the urethra e e e




D. Severe infection in the kidney pelvis
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Answer: A e




Rationale: The severe pain (renal colic) from renal calculi occurs when a stone becomes
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, too large to move easily through the ureter, causing obstruction, stretching of the ureter,
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and intense pain.
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Question 6 e




What is the term for a reduction in red blood cells, white blood cells, and platelets?
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A. Aplastic anemia e




B. Hereditary hemochromatosis e




C. Myelodysplastic syndrome e




D. Sideroblastic anemia e




Answer: A e




Rationale: Aplastic anemia is characterized by pancytopenia—a reduction in all three
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e blood cell types (red blood cells, white blood cells, and platelets) due to bone marrow
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e failure.




Question 7 e




Describe what you expect values to be if the patient has type 2 diabetes.
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A. Both blood glucose and HbA1c should be elevated
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B. Only blood glucose should be elevated
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C. Only HbA1c should be elevated
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D. Both should be normal
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Answer: A e




Rationale: In type 2 diabetes, both current blood glucose levels and HbA1c (reflecting
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average glucose over 2-3 months) are elevated.
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Question 8 e




What is the most common cause of hypoxemia?
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