NURS 3209 MEDICATION ADMINISTRATION EXAM PRACTICE
QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS)
PLUS RATIONALES Q&A INSTANT DOWNLOAD PDF
140 QUESTIONS
TABLE OF CONTENTS
# TOPIC
1 Apply pharmacokinetic and pharmacodynamic principles to individualize drug therapy
2 Calculate and verify medication dosages using dimensional analysis and interpret drug labels
3 Identify and mitigate risks associated with high-alert medications and look-alike/sound-alike drugs
4 Evaluate patient response to medications and intervene appropriately
5 Integrate legal, ethical, and regulatory standards into medication administration practice
6 NURS 3209 Medication Administration Exam Practice Questions And Correct Answers
7 Verified Answers
8 Plus Rationales Q&A Instant Download Pdf
9 Foundations of Pharmacology and Medication Administration
10 Applied Pharmacology and Medication Administration
11 Advanced Pharmacology and Medication Administration
12 Pharmacology and Medication Administration Review
Page 1
,Q1 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
A patient with chronic kidney disease (CrCl 25 mL/min) is prescribed a medication
that is primarily renally excreted. The nurse reviews the drug reference and notes
the half-life is 12 hours in normal renal function. Which adjustment is most
appropriate based on pharmacokinetic principles?
A. Increase the dose to achieve therapeutic effect.
B. Administer the drug more frequently to maintain steady state.
C. Extend the dosing interval or reduce the dose. CORRECT
D. No adjustment needed if the drug is protein-bound.
RATIONALE: In renal impairment, drug excretion decreases, leading to accumulation and
prolonged half-life. To avoid toxicity, dosing interval should be extended or dose reduced.
Increasing dose or frequency would worsen accumulation. Protein binding does not negate renal
clearance issues.
Q2 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
During a medication reconciliation, a patient reports taking an herbal supplement
that inhibits CYP3A4. Which of the following prescription medications is most
likely to reach toxic levels due to this interaction?
A. Warfarin
B. Simvastatin CORRECT
C. Metformin
D. Levothyroxine
RATIONALE: Simvastatin is extensively metabolized by CYP3A4; inhibition increases its plasma
concentration, raising the risk of rhabdomyolysis. Warfarin is metabolized by CYP2C9, metformin
is renally excreted, and levothyroxine is not CYP3A4-dependent.
Page 2
,Q3 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
A nurse is preparing to administer an IV push medication that is incompatible with
the current IV fluid. Which action is the most appropriate to maintain patient safety
and drug efficacy?
A. Flush the line with normal saline before and after administration. CORRECT
B. Administer the drug through a different lumen of a multilumen catheter.
C. Stop the IV fluid, administer the drug, then restart the fluid.
D. Dilute the drug in the IV fluid to reduce incompatibility.
RATIONALE: Flushing with a compatible solution (e.g., normal saline) before and after
administration prevents mixing of incompatible solutions. Using a different lumen does not avoid
mixing if fluids share a common line. Stopping the fluid may not clear the line. Dilution does not
guarantee compatibility.
Q4 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
A patient with type 2 diabetes is prescribed metformin. The nurse reviews the
electronic health record and notes a recent order for IV contrast for a CT scan.
Which action is most appropriate?
A. Administer metformin as usual.
B. Hold metformin at the time of the scan and for 48 hours after. CORRECT
C. Increase the metformin dose to compensate for contrast effects.
D. Switch to insulin for the day of the scan.
RATIONALE: Metformin carries a risk of lactic acidosis with IV contrast in patients with renal
impairment or hepatic dysfunction. Current guidelines recommend holding metformin at the time
of contrast administration and for 48 hours afterward, then restarting if renal function is stable.
Administering as usual increases risk; increasing dose is unsafe; switching to insulin is not
routine unless hyperglycemia requires it.
Page 3
, Q5 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
A nurse is using the 'rights of medication administration' to prevent errors. Which
scenario demonstrates an additional 'right' that addresses high-alert medications?
A. Verifying the patient's identity with two identifiers.
B. Documenting the medication immediately after administration.
C. Having a second nurse independently double-check the calculated dose. CORRECT
D. Checking the expiration date on the medication vial.
RATIONALE: For high-alert medications (e.g., heparin, insulin), independent double-checks are a
safety strategy beyond the basic rights. Two identifiers, documentation, and expiration checks are
standard but not specific to high-alert medications.
Page 4
QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS)
PLUS RATIONALES Q&A INSTANT DOWNLOAD PDF
140 QUESTIONS
TABLE OF CONTENTS
# TOPIC
1 Apply pharmacokinetic and pharmacodynamic principles to individualize drug therapy
2 Calculate and verify medication dosages using dimensional analysis and interpret drug labels
3 Identify and mitigate risks associated with high-alert medications and look-alike/sound-alike drugs
4 Evaluate patient response to medications and intervene appropriately
5 Integrate legal, ethical, and regulatory standards into medication administration practice
6 NURS 3209 Medication Administration Exam Practice Questions And Correct Answers
7 Verified Answers
8 Plus Rationales Q&A Instant Download Pdf
9 Foundations of Pharmacology and Medication Administration
10 Applied Pharmacology and Medication Administration
11 Advanced Pharmacology and Medication Administration
12 Pharmacology and Medication Administration Review
Page 1
,Q1 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
A patient with chronic kidney disease (CrCl 25 mL/min) is prescribed a medication
that is primarily renally excreted. The nurse reviews the drug reference and notes
the half-life is 12 hours in normal renal function. Which adjustment is most
appropriate based on pharmacokinetic principles?
A. Increase the dose to achieve therapeutic effect.
B. Administer the drug more frequently to maintain steady state.
C. Extend the dosing interval or reduce the dose. CORRECT
D. No adjustment needed if the drug is protein-bound.
RATIONALE: In renal impairment, drug excretion decreases, leading to accumulation and
prolonged half-life. To avoid toxicity, dosing interval should be extended or dose reduced.
Increasing dose or frequency would worsen accumulation. Protein binding does not negate renal
clearance issues.
Q2 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
During a medication reconciliation, a patient reports taking an herbal supplement
that inhibits CYP3A4. Which of the following prescription medications is most
likely to reach toxic levels due to this interaction?
A. Warfarin
B. Simvastatin CORRECT
C. Metformin
D. Levothyroxine
RATIONALE: Simvastatin is extensively metabolized by CYP3A4; inhibition increases its plasma
concentration, raising the risk of rhabdomyolysis. Warfarin is metabolized by CYP2C9, metformin
is renally excreted, and levothyroxine is not CYP3A4-dependent.
Page 2
,Q3 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
A nurse is preparing to administer an IV push medication that is incompatible with
the current IV fluid. Which action is the most appropriate to maintain patient safety
and drug efficacy?
A. Flush the line with normal saline before and after administration. CORRECT
B. Administer the drug through a different lumen of a multilumen catheter.
C. Stop the IV fluid, administer the drug, then restart the fluid.
D. Dilute the drug in the IV fluid to reduce incompatibility.
RATIONALE: Flushing with a compatible solution (e.g., normal saline) before and after
administration prevents mixing of incompatible solutions. Using a different lumen does not avoid
mixing if fluids share a common line. Stopping the fluid may not clear the line. Dilution does not
guarantee compatibility.
Q4 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
A patient with type 2 diabetes is prescribed metformin. The nurse reviews the
electronic health record and notes a recent order for IV contrast for a CT scan.
Which action is most appropriate?
A. Administer metformin as usual.
B. Hold metformin at the time of the scan and for 48 hours after. CORRECT
C. Increase the metformin dose to compensate for contrast effects.
D. Switch to insulin for the day of the scan.
RATIONALE: Metformin carries a risk of lactic acidosis with IV contrast in patients with renal
impairment or hepatic dysfunction. Current guidelines recommend holding metformin at the time
of contrast administration and for 48 hours afterward, then restarting if renal function is stable.
Administering as usual increases risk; increasing dose is unsafe; switching to insulin is not
routine unless hyperglycemia requires it.
Page 3
, Q5 APPLY PHARMACOKINETIC AND PHARMACODYNAMIC PRINCIPLES TO INDIVIDUALIZE
DRUG THERAPY
A nurse is using the 'rights of medication administration' to prevent errors. Which
scenario demonstrates an additional 'right' that addresses high-alert medications?
A. Verifying the patient's identity with two identifiers.
B. Documenting the medication immediately after administration.
C. Having a second nurse independently double-check the calculated dose. CORRECT
D. Checking the expiration date on the medication vial.
RATIONALE: For high-alert medications (e.g., heparin, insulin), independent double-checks are a
safety strategy beyond the basic rights. Two identifiers, documentation, and expiration checks are
standard but not specific to high-alert medications.
Page 4
