WGU D398 PHARMACOLOGY EXAM 1
(2026/2027) QUESTIONS AND CORRECT
ANSWERS GRADED A+
1. Symptoms of Parkinsonism would be increased by
A. excess levels of acetylcholine
B. treatment with some antipsychotic drugs
C. decreased levels of dopamine
D. drug administration after a high-protein meal
E. all of these
I had ABC highlighted I think this was a mistake please edit
2. The drug classified as a dopamine receptor agonist is
A. amantadine
B. benztropine
C. ropinirole
D. entacapone (COMT)
E. carbidopa
C. ropinirole
,3. Select the drugs that increase the duration of action of DA and/or the amount of
levodopa that enters the brain.
A. carbidopa
B. tolcapone
C. selegiline
D. rasagiline
E. all of these
E. all of these
4. In Parkinson's disease, slowed movements are defined as
A. rigidity
B. bradykinesia
C. tremor
D. dystonia
E. postural instability
B. bradykinesia
5. Sinemet is the trade name of a drug combination that contains levodopa and
A. carbidopa and entacapone
B. entacapone
C. carbidopa
,D. selegiline
E. amantadine
C. carbidopa
6. The COMT inhibitor that has been associated with causing liver toxicity is
A. ropinirole
B. entacapone
C. pramipexole
D. tolcapone
E. benztropine
D. tolcapone
7. Select the symptoms of Parkinson's disease
A. muscular rigidity
B. increased sweating
C. salivary drooling
D. movement disturbances
E. all of these
A and D
, 8. Which of the following drugs would be used to decrease the actions of ACH?
A. amantadine
B. levodopa
C. bromocriptine
D. procyclidine
E. carbidopa
D. procyclidine
9. Select the mechanisms by which levodopa works.
A. crosses blood-brain barrier by an amino acid transporter
B. converted to dopamine in the substantia nigra neurons
C. increases level of dopamine in the brain
D. peripheral metabolism to DA inhibited by carbidopa
E. all of these
E. all of these
10. Apomorphine is classified as
A. MAO-B inhibitor
B. dopamine receptor agonist
C. COMT inhibitor
(2026/2027) QUESTIONS AND CORRECT
ANSWERS GRADED A+
1. Symptoms of Parkinsonism would be increased by
A. excess levels of acetylcholine
B. treatment with some antipsychotic drugs
C. decreased levels of dopamine
D. drug administration after a high-protein meal
E. all of these
I had ABC highlighted I think this was a mistake please edit
2. The drug classified as a dopamine receptor agonist is
A. amantadine
B. benztropine
C. ropinirole
D. entacapone (COMT)
E. carbidopa
C. ropinirole
,3. Select the drugs that increase the duration of action of DA and/or the amount of
levodopa that enters the brain.
A. carbidopa
B. tolcapone
C. selegiline
D. rasagiline
E. all of these
E. all of these
4. In Parkinson's disease, slowed movements are defined as
A. rigidity
B. bradykinesia
C. tremor
D. dystonia
E. postural instability
B. bradykinesia
5. Sinemet is the trade name of a drug combination that contains levodopa and
A. carbidopa and entacapone
B. entacapone
C. carbidopa
,D. selegiline
E. amantadine
C. carbidopa
6. The COMT inhibitor that has been associated with causing liver toxicity is
A. ropinirole
B. entacapone
C. pramipexole
D. tolcapone
E. benztropine
D. tolcapone
7. Select the symptoms of Parkinson's disease
A. muscular rigidity
B. increased sweating
C. salivary drooling
D. movement disturbances
E. all of these
A and D
, 8. Which of the following drugs would be used to decrease the actions of ACH?
A. amantadine
B. levodopa
C. bromocriptine
D. procyclidine
E. carbidopa
D. procyclidine
9. Select the mechanisms by which levodopa works.
A. crosses blood-brain barrier by an amino acid transporter
B. converted to dopamine in the substantia nigra neurons
C. increases level of dopamine in the brain
D. peripheral metabolism to DA inhibited by carbidopa
E. all of these
E. all of these
10. Apomorphine is classified as
A. MAO-B inhibitor
B. dopamine receptor agonist
C. COMT inhibitor
