BIOC 384 SMARTWORK 12 TH EDITION
ACCOMPANIED WITH FULL QUESTIONS
AND CORRECT ANSWERS
In the figure above, oxygen consumption and ATP synthesis increase with the addition of succinate and
ADP + Pi. Which of the following will have to accept electrons from succinate in order for oxidative
phosphorylation to occur? - Correct Answer: Complex !!
Which of the following modifications to this experiment would diminish or completely eliminate ATP
synthesis using succinate and ADP + Pi as substrates? - Correct Answer: inhibition of Complex III with
antimycin
dissipation of the proton gradient across the inner membrane of the mitochondria with 2,4-
dinitrophenol
inhibition of Complex IV with cyanide
Which enzyme is crucial for transfer of electrons from cytosolic NADH into the mitochondrial matrix in
muscle cells? - Correct Answer: Glycerol-3-P dehydrogenase
Inherited mitochondrial diseases - Correct Answer: can pass to the next generation only through
mitochondrial gene mutations in females.
In this molecular structure, three amino acid side chains and ANP are interacting with a single Mg2+
atom. Zoom in on each enzyme-derived amino acid side chain and identify the amino acids. Remember
that carbon atoms are shown in gray and oxygen atoms in red. What amino acids are shown to be
interacting with Mg2+? - Correct Answer: one threonine and two glutamates
In the model above, the α subunit is shown in magenta and the β subunit in green. The location of the
ATP synthase complex active site can be best described as being found - Correct Answer: at the interface
between the α and β subunits.
ACCOMPANIED WITH FULL QUESTIONS
AND CORRECT ANSWERS
In the figure above, oxygen consumption and ATP synthesis increase with the addition of succinate and
ADP + Pi. Which of the following will have to accept electrons from succinate in order for oxidative
phosphorylation to occur? - Correct Answer: Complex !!
Which of the following modifications to this experiment would diminish or completely eliminate ATP
synthesis using succinate and ADP + Pi as substrates? - Correct Answer: inhibition of Complex III with
antimycin
dissipation of the proton gradient across the inner membrane of the mitochondria with 2,4-
dinitrophenol
inhibition of Complex IV with cyanide
Which enzyme is crucial for transfer of electrons from cytosolic NADH into the mitochondrial matrix in
muscle cells? - Correct Answer: Glycerol-3-P dehydrogenase
Inherited mitochondrial diseases - Correct Answer: can pass to the next generation only through
mitochondrial gene mutations in females.
In this molecular structure, three amino acid side chains and ANP are interacting with a single Mg2+
atom. Zoom in on each enzyme-derived amino acid side chain and identify the amino acids. Remember
that carbon atoms are shown in gray and oxygen atoms in red. What amino acids are shown to be
interacting with Mg2+? - Correct Answer: one threonine and two glutamates
In the model above, the α subunit is shown in magenta and the β subunit in green. The location of the
ATP synthase complex active site can be best described as being found - Correct Answer: at the interface
between the α and β subunits.
