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NR 565 - Advanced Pharmacology Midterm Exam Newest 2026/2027 Questions and Correct Detailed Answers Already Graded A+

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NR 565 - Advanced Pharmacology Midterm Exam Newest 2026/2027 Questions and Correct Detailed Answers Already Graded A+

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NR 565 - Advanced Pharmacology Midterm Exam
Newest 2026/2027 Questions and Correct Detailed
Answers Already Graded A+



1st trimester (fetus most at risk d/t rapid growth) - CORRECT ANSWER-During
what trimester is a pregnant woman most at risk for adverse drug reactions with
potential long term consequences?




Calculate total daily dose: 1. daily amount of each opioid that patient takes 2.
convert to MME, multiply dose for each opioid by conversion factor 3. add them
together - CORRECT ANSWER-What is used to calculate pt's overdose risk?



morphine milligram equivalent, represents the potency of an opioid in
comparison to morphine, used to identify opioid prescription burden of a person -
CORRECT ANSWER-What is MME and when to use?




electronic databases enable providers to access information regarding a patient's
prescription history of controlled substances. Nearly all states have implemented
PDMPs, and some states require providers to check the PDMP before prescribing
controlled substances. - CORRECT ANSWER-What is the prescription drug
monitoring program?

,anytime a controlled substance is prescribed, refilled, or filled - CORRECT
ANSWER-When should PDMP be used?




identify those at risk for overdose - CORRECT ANSWER-Why is PDMP
important?



Urine test at least yearly

PDMP routinely - CORRECT ANSWER-Assess someone for possible drug
diversion?



Patients with renal or hepatic insufficiency can experience greater peak effect and
longer duration of action for medications, thereby reducing the dose at which
respiratory depression and overdose may occur. Similarly, for patients ages 65
years and older, reduced renal function and medication clearance due to age can
result in a smaller therapeutic window between safe dosages and dosages
associated with respiratory depression and overdose. - CORRECT ANSWER-
How does renal and hepatic function impact medication levels in body?



Older adults metabolize opioids slowly and therefore require lower doses than
younger adults. - CORRECT ANSWER-How do elderly metabolize differently
than younger people?

,with every opioid prescription - CORRECT ANSWER-When should naloxone be
prescribed?



4 mg, nasal spray- one spray to one nostril

If no response, additional doses can be given every 2 to 3 minutes until
emergency services arrive - CORRECT ANSWER-What is the typical dose of
naloxone and how is it administered?



Dosage must be titrated carefully bc if too much is given the patient will swing
from a state of intoxication to withdrawal - CORRECT ANSWER-In regards to
dosage, why do we need to be cautious when giving naloxone?



Short- naloxone must be administered every few hours until opioid
concentrations have dropped to nontoxic levels - CORRECT ANSWER-What is
the half-life of naloxone?



Recommendations of medications inappropriate for elderly (65 and older),
prescriber ultimately decides - CORRECT ANSWER-What is BEERS criteria?

, liver enzyme system where medications are metabolized, can either be inducers
or inhibitors and create drug-drug interactions - CORRECT ANSWER-What is
the CYP450 (cytochrome P450)



Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect
(decrease blood levels of drug), elevate CYP450 enzymes - CORRECT ANSWER-
CYP450 inducers



"Bullshit Crap GPS INDUCES rage" - CORRECT ANSWER-CYP450 inducers
pneumonic



Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin,
griseofulvin, phenobarbital, sulfonylureas - CORRECT ANSWER-CYP450 inducer
drug names



inhibit metabolism, increase blood levels of medications - CORRECT ANSWER-
CYP450 inhibitors



"VISA credit card debt INHIBITS spending on designers like CK to look GQ" -
CORRECT ANSWER-CYP450 pneumonic

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